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Full-Text Articles in Medicine and Health Sciences

Characterisation Of Dendritic Cells Arising From Progenitors Endogenous To Murine Spleen, Sawang Petvises, Helen O'Neill Feb 2014

Characterisation Of Dendritic Cells Arising From Progenitors Endogenous To Murine Spleen, Sawang Petvises, Helen O'Neill

Helen O'Neill

Heterogeneity amongst dendritic cell (DC) subsets leads to a spectrum of immune response capacity against pathogens. Several DC subsets in spleen have been described which differ in terms of phenotype and function. We have previously reported a distinct population of CD11cloCD11b hiMHC-II-CD8- dendritic-like "L-DC" in murine spleen, which can also be generated in splenic stromal longterm cultures. Here, the ontogeny of L-DC development in perinatal mice has been compared with other known splenic DC subsets. Flow cytometric analysis has revealed the presence of L-DC at embryonic age (E)18.5 spleen, while plasmacytoid (p)DC and conventional (c)DC appear at 2 and 4 …


Community Health And Socioeconomic Issues Surrounding Concentrated Animal Feeding Operations., Kelley Donham, Steven Wing, David Osterberg, Jan Flora, Carol Hodne, Kendall Thu, Peter Thorne Jan 2014

Community Health And Socioeconomic Issues Surrounding Concentrated Animal Feeding Operations., Kelley Donham, Steven Wing, David Osterberg, Jan Flora, Carol Hodne, Kendall Thu, Peter Thorne

David Osterberg

A consensus of the Workgroup on Community and Socioeconomic Issues was that improving and sustaining healthy rural communities depends on integrating socioeconomic development and environmental protection. The workgroup agreed that the World Health Organization's definition of health, "a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity," applies to rural communities. These principles are embodied in the following main points agreed upon by this workgroup. Healthy rural communities ensure a) the physical and mental health of individuals, b) financial security for individuals and the greater community, c) social well-being, d ) social …