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Full-Text Articles in Medicine and Health Sciences

Adjuvant Concurrent Chemoradiation Using Intensity-Modulated Radiotherapy And Simultaneous Integrated Boost For Resected High-Risk Adenocarcinoma Of The Distal Esophagus And Gastro-Esophageal Junction., Brian Yaremko, David Palma, Abigail Erickson, Gregory Pierce, Richard Malthaner, Richard Inculet, Rashid Dar, George Rodrigues, Edward Yu Jul 2015

Adjuvant Concurrent Chemoradiation Using Intensity-Modulated Radiotherapy And Simultaneous Integrated Boost For Resected High-Risk Adenocarcinoma Of The Distal Esophagus And Gastro-Esophageal Junction., Brian Yaremko, David Palma, Abigail Erickson, Gregory Pierce, Richard Malthaner, Richard Inculet, Rashid Dar, George Rodrigues, Edward Yu

Richard A. Malthaner

Purpose: Multimodality therapy leads to improved outcomes for adenocarcinoma of the distal esophagus and gastroesophageal junction (GEJ) over surgery alone. At our institution, adjuvant chemoradiation (chemoRT) using IMRT and SIB is standard of care for resected high-risk disease. In this study, we review our experience with a recent cohort of patients treated in this manner. Methods and materials: We identified 18 patients with resected T3 and/or N1 adenocarcinoma of the distal esophagus and GEJ who received adjuvant chemoRT. A large elective volume (PTV1) and a smaller high-risk volume (PTV2) were irradiated simultaneously using IMRT and an SIB technique. All patients …


Adjuvant Concurrent Chemoradiation Using Intensity-Modulated Radiotherapy And Simultaneous Integrated Boost For Resected High-Risk Adenocarcinoma Of The Distal Esophagus And Gastro-Esophageal Junction., Brian Yaremko, David Palma, Abigail Erickson, Gregory Pierce, Richard Malthaner, Richard Inculet, Rashid Dar, George Rodrigues, Edward Yu Jul 2015

Adjuvant Concurrent Chemoradiation Using Intensity-Modulated Radiotherapy And Simultaneous Integrated Boost For Resected High-Risk Adenocarcinoma Of The Distal Esophagus And Gastro-Esophageal Junction., Brian Yaremko, David Palma, Abigail Erickson, Gregory Pierce, Richard Malthaner, Richard Inculet, Rashid Dar, George Rodrigues, Edward Yu

Richard A. Malthaner

Purpose: Multimodality therapy leads to improved outcomes for adenocarcinoma of the distal esophagus and gastroesophageal junction (GEJ) over surgery alone. At our institution, adjuvant chemoradiation (chemoRT) using IMRT and SIB is standard of care for resected high-risk disease. In this study, we review our experience with a recent cohort of patients treated in this manner. Methods and materials: We identified 18 patients with resected T3 and/or N1 adenocarcinoma of the distal esophagus and GEJ who received adjuvant chemoRT. A large elective volume (PTV1) and a smaller high-risk volume (PTV2) were irradiated simultaneously using IMRT and an SIB technique. All patients …


Amdis Case Conference: Intrusive Medication Safety Alerts, J. Graham, Donald Levick, R. Schreiber Jul 2013

Amdis Case Conference: Intrusive Medication Safety Alerts, J. Graham, Donald Levick, R. Schreiber

Donald Levick MD

No abstract provided.


A Qualitative Review Of Differential Diagnosis Generators, William Bond Md, Ms, Linda M. Schwartz Mde, Ahip, Cm, Kevin R. Weaver Do, Donald Levick Md, Mba, Michael Guliano Md, Med, Mhpe, Mark L. Graber Md Jul 2013

A Qualitative Review Of Differential Diagnosis Generators, William Bond Md, Ms, Linda M. Schwartz Mde, Ahip, Cm, Kevin R. Weaver Do, Donald Levick Md, Mba, Michael Guliano Md, Med, Mhpe, Mark L. Graber Md

Donald Levick MD

No abstract provided.


Clinical Decision Support (Cds) & Meaningful Use Frequently Asked Questions, Paul Kleeberg, Donald Levick, Jerome Osheroff, Jacob Reider, Jonathan Teich Jul 2013

Clinical Decision Support (Cds) & Meaningful Use Frequently Asked Questions, Paul Kleeberg, Donald Levick, Jerome Osheroff, Jacob Reider, Jonathan Teich

Donald Levick MD

No abstract provided.


Health System Automates Medication Reconciliation. Solution Extracts Information Directly From The Clinical System Throughout A Patient's Stay And At Discharge, Donald Levick, Sandra Haldeman, Michelle Beck Jul 2013

Health System Automates Medication Reconciliation. Solution Extracts Information Directly From The Clinical System Throughout A Patient's Stay And At Discharge, Donald Levick, Sandra Haldeman, Michelle Beck

Donald Levick MD

No abstract provided.


Improving Outcomes With Clinical Decision Support: An Implementer's Guide, Jerome Osheroff, Jonathan Teich, Donald Levick, Luis Saldana, Ferdinand Velasco, Dean Sittig, Kendall Rogers, Robert Jenders Jul 2013

Improving Outcomes With Clinical Decision Support: An Implementer's Guide, Jerome Osheroff, Jonathan Teich, Donald Levick, Luis Saldana, Ferdinand Velasco, Dean Sittig, Kendall Rogers, Robert Jenders

Donald Levick MD

No abstract provided.


Physician Buy-In For Emr's, L. Yackanicz, R. Kerr, Donald Levick Jul 2013

Physician Buy-In For Emr's, L. Yackanicz, R. Kerr, Donald Levick

Donald Levick MD

No abstract provided.


Adjuvant Concurrent Chemoradiation Using Intensity-Modulated Radiotherapy And Simultaneous Integrated Boost For Resected High-Risk Adenocarcinoma Of The Distal Esophagus And Gastro-Esophageal Junction., Brian Yaremko, David Palma, Abigail Erickson, Gregory Pierce, Richard Malthaner, Richard Inculet, Rashid Dar, George Rodrigues, Edward Yu Feb 2013

Adjuvant Concurrent Chemoradiation Using Intensity-Modulated Radiotherapy And Simultaneous Integrated Boost For Resected High-Risk Adenocarcinoma Of The Distal Esophagus And Gastro-Esophageal Junction., Brian Yaremko, David Palma, Abigail Erickson, Gregory Pierce, Richard Malthaner, Richard Inculet, Rashid Dar, George Rodrigues, Edward Yu

Edward Yu

Purpose: Multimodality therapy leads to improved outcomes for adenocarcinoma of the distal esophagus and gastroesophageal junction (GEJ) over surgery alone. At our institution, adjuvant chemoradiation (chemoRT) using IMRT and SIB is standard of care for resected high-risk disease. In this study, we review our experience with a recent cohort of patients treated in this manner. Methods and materials: We identified 18 patients with resected T3 and/or N1 adenocarcinoma of the distal esophagus and GEJ who received adjuvant chemoRT. A large elective volume (PTV1) and a smaller high-risk volume (PTV2) were irradiated simultaneously using IMRT and an SIB technique. All patients …


Use Of Health Information Technology For Higher-Value Critical Care, Lena Chen, Edward Kennedy, Anne Sales, Timothy Hofer Dec 2012

Use Of Health Information Technology For Higher-Value Critical Care, Lena Chen, Edward Kennedy, Anne Sales, Timothy Hofer

Edward H. Kennedy

To illustrate how data from a comprehensive EHR might contribute to better triage decisions, we examined the records of a cohort of 101,912 patients admitted for reasons other than surgery to 121 VA acute care hospitals in fiscal year 2009. Critical care guidelines continue to maintain that the ICU is the place to care for “the most seriously ill patients.” For the most common noncardiac diagnoses, we found that, in keeping with this guideline, patients with a high severity of illness were much more likely to be admitted to the ICU than were patients with a low severity of illness. …


Improved Cardiovascular Risk Prediction Using Nonparametric Regression And Electronic Health Record Data, Edward Kennedy, Wyndy Wiitala, Rodney Hayward, Jeremy Sussman Dec 2012

Improved Cardiovascular Risk Prediction Using Nonparametric Regression And Electronic Health Record Data, Edward Kennedy, Wyndy Wiitala, Rodney Hayward, Jeremy Sussman

Edward H. Kennedy

Use of the electronic health record (EHR) is expected to increase rapidly in the near future, yet little research exists on whether analyzing internal EHR data using flexible, adaptive statistical methods could improve clinical risk prediction. Extensive implementation of EHR in the Veterans Health Administration provides an opportunity for exploration. Our objective was to compare the performance of various approaches for predicting risk of cerebrovascular and cardiovascular (CCV) death, using traditional risk predictors versus more comprehensive EHR data. Regression methods outperformed the Framingham risk score, even with the same predictors (AUC increased from 71% to 73% and calibration also improved). …