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Invited Commentary On: Orthotopic Heart Transplantation In Patients With Metabolic Risk Factors, Nicholas Cavarocchi, Paul Mather

Nicholas C Cavarocchi MDJ

This is invited commentary to the following article: Kilic, A., Conte, J. V., Shah, A. S., & Yuh, D. D. (2012). Orthotopic heart transplantation in patients with metabolic risk factors. Annals of Thoracic Surgery, 93(3), 718-724.

Ecmo-State Of The Art, Nicholas Cavarorocchi, Md

Nicholas C Cavarocchi MDJ

Dr. Cavarocchi is an Associate Professor of Surgery who holds a faculty appointment in the Department of Surgery at Thomas Jefferson University Hospital in Philadelphia, PA. He is also the Director of Cardiac Critical Care and Surgical Care Unit at Jefferson. In 2007, he was names as one of the countries top surgeons. He specializes in cardiothoracic surgery.

Presentation runs for 1 hour and 2 minutes.

Anomalous Right Coronary Artery Arising From The Pulmonary Artery, Ashish Kabra, James Wu, Matthew Martinez

James K Wu MD

No abstract provided.

Fabry's Disease With Lvot Obstruction: Diagnosis And Management, Jacob Blount, James Wu, Matthew Martinez

James K Wu MD

A 46-year-old male was diagnosed with hypertrophic cardiomyopathy (HCM) and severe left ventricular outflow tract (LVOT) obstruction. Genetic testing revealed that this was a "mimic of HCM" and the true diagnosis was Fabry's disease, although there were no other clinical features of Fabry's. Despite maximal medical therapy he remained symptomatic from the outflow tract gradient and required surgical myectomy for symptom relief. This case illustrates the diagnosis of an HCM mimic by genetic testing.

Durability, Reliability, Viability: 48 Year-Survival Of A Starr-Edwards Mitral Valve, Bilal Ayub, Justin Guthier, James Wu

James K Wu MD

No abstract provided.

Venous Thromboembolism In Patients With Heart Failure: In-Hospital And Chronic Use Of Anti-Coagulants For Prevention, Nasir Shariff, Abdul Aleem, Vadim Levin, Sudip Nanda, Matthew Martinez, Stacey Smith, Ronald Freudenberger

Vadim A Levin MD

No abstract provided.

Ranolazine—Treatment Of Ventricular Tachycardia And Symptomatic Ventricular Premature Beats In Ischemic Cardiomyopathy, Sudip Nanda, Vadim Levin, Matthew Martinez, Ronald Freudenberger

Vadim A Levin MD

No abstract provided.

Atrial Fibrillation In Patients With Heart Failure: Role Of Catheter Ablation Therapies, Nasir Shariff, Abdul Aleem, Vadim Levin, Mukesh Singh, Nauman Islam, Ronald Freudenberger

Vadim A Levin MD

No abstract provided.

Interatrial Conduction Correlates With Optimal Atrioventricular Timing In Cardiac Resynchronization Therapy Devices, Vadim Levin, Mehdi Razavi, Robert Coll, James Coles, Aleksandre Sambelashvili

Vadim A Levin MD

No abstract provided.

Dabigatran: A New Chapter In Anticoagulation, Shawn Ahmed, Vadim Levin, Robert Malacoff, Matthew Martinez

Vadim A Levin MD

No abstract provided.

Novel Oral Anticoagulants For Stroke Prevention In Patients With Atrial Fibrillation: Dawn Of A New Era, Tahmeed Contractor, Vadim Levin, Matthew Martinez, Francis Marchinski

Vadim A Levin MD

No abstract provided.

Managing A Cardiac Emergency, C Midei, Terry Capuano

Terry A Capuano MBA, MSN, RN, FACHE, NE-BC

No abstract provided.

Bridging The Care Continuum For Open Heart Surgery Patients, Terry Capuano, Reia Barber, Kathleen Sullivan

Terry A Capuano MBA, MSN, RN, FACHE, NE-BC

No abstract provided.

Boomerang-Shaped Heart In Isolated Dextroversion, Eddie Kim, Ravi Desai, Harish Doppalapudi, Steven Lloyd

Ravi V Desai MD

No abstract provided.

Impact Of Baseline Systolic Blood Pressure On Long-Term Outcomes In Patients With Advanced Chronic Systolic Heart Failure (Insights From The Best Trial), Ravi Desai, Maciej Banach, Mustafa Ahmed, Marjan Mujib, Inmaculada Aban, Thomas Love, Michel White, Gregg Fonarow, Prakash Deedwania, Wilbert Aronow, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Mast Cell Stabilization Decreases Cardiomyocyte And Lv Function In Dogs With Isolated Mitral Regurgitation., Betty Pat, Cheryl Killingsworth, Yuanwen Chen, James D Gladden, Greg Walcott, Pamela C Powell, Thomas Denney, Himanshu Gupta, Ravi Desai, Michael Tillson, A Ray Dillon, Louis J Dell'italia

Ravi V Desai MD

BACKGROUND: Mast cells are increased in isolated mitral regurgitation (MR) in the dog and may mediate extracellular matrix loss and left ventricular (LV) dilatation. We tested the hypothesis that mast cell stabilization would attenuate LV remodeling and improve function in the MR dog.

METHODS AND RESULTS: MR was induced in adult dogs randomized to no treatment (MR, n = 5) or to the mast cell stabilizer, ketotifen (MR + MCS, n = 4) for 4 months. LV hemodynamics were obtained at baseline and after 4 months of MR and magnetic resonance imaging (MRI) was performed at sacrifice. MRI-derived, serial, short-axis …

Natural History Of Concentric Left Ventricular Geometry In Community-Dwelling Older Adults Without Heart Failure During Seven Years Of Follow-Up, Ravi Desai, Mustafa Ahmed, Marjan Mujib, Inmaculada Aban, Michael Zile, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Absence Of Obesity Paradox In Patients With Chronic Heart Failure And Diabetes Mellitus: A Propensity-Matched Study, Chris Adamopoulos, Philippe Meyer, Ravi Desai, Kyparissi Karatzidou, Fernando Ovalle, Michel White, Inmaculada Aban, Thomas Love, Prakash Deedwania, Stefan Anker, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Chymase Inhibition Prevents Fibronectin And Myofibrillar Loss And Improves Cardiomyocyte Function And Lv Torsion Angle In Dogs With Isolated Mitral Regurgitation., Betty Pat, Yuanwen Chen, Cheryl Killingsworth, James D Gladden, Ke Shi, Junying Zheng, Pamela C Powell, Greg Walcott, Mustafa I Ahmed, Himanshu Gupta, Ravi Desai, Chih-Chang Wei, Naoki Hase, Tsunefumi Kobayashi, Abdelkarim Sabri, Henk Granzier, Thomas Denney, Michael Tillson, A Ray Dillon, Ahsan Husain, Louis J Dell'italia

Ravi V Desai MD

BACKGROUND: The left ventricular (LV) dilatation of isolated mitral regurgitation (MR) is associated with an increase in chymase and a decrease in interstitial collagen and extracellular matrix. In addition to profibrotic effects, chymase has significant antifibrotic actions because it activates matrix metalloproteinases and kallikrein and degrades fibronectin. Thus, we hypothesize that chymase inhibitor (CI) will attenuate extracellular matrix loss and LV remodeling in MR.

METHODS AND RESULTS: We studied dogs with 4 months of untreated MR (MR; n=9) or MR treated with CI (MR+CI; n=8). Cine MRI demonstrated a >40% increase in LV end-diastolic volume in both groups, consistent with …

Effect Of Serum Insulin On The Association Between Hyperuricemia And Incident Heart Failure, Ravi Desai, Mustafa Ahmed, Gregg Fonarow, Gerasimos Filippatos, Michel White, Inmaculada Aban, Wilbert Aronow, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Relation Of Baseline Systolic Blood Pressure And Long-Term Outcomes In Ambulatory Patients With Chronic Mild To Moderate Heart Failure, Maciej Banach, Vikas Bhatia, Margaret Feller, Marjan Mujib, Ravi Desai, Mustafa Ahmed, Jason Guichard, Inmaculada Aban, Thomas Love, Wilbert Aronow, Michel White, Prakash Deedwania, Gregg Fonarow, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Warfarin Use And Outcomes In Patients With Advanced Chronic Systolic Heart Failure Without Atrial Fibrillation, Prior Thromboembolic Events, Or Prosthetic Valves, Marjan Mujib, Abu-Ahmed Rahman, Ravi Desai, Mustafa Ahmed, Margaret Feller, Inmaculada Aban, Tomas Love, Michel White, Prakash Deedwania, Wilbert Aronow, Gregg Fonarow, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Unusual Mechanism Of Tricuspid Regurgitation In Ventricular Septal Defect, Ravi Desai, Frank Seghatol-Eslami, Fatemeh Nabavizadeh, Steven Lloyd

Ravi V Desai MD

No abstract provided.

Influence Of Co-Existing Atrial Fibrillation On The Efficacy Of Atorvastatin Treatment In Patients With Dilated Cardiomyopathy: A Pilot Study, Agata Bielecka-Dabrowa, Jan Goch, Jacek Rysz, Marek Maciejewski, Ravi Desai, Wilbert Aronow

Ravi V Desai MD

No abstract provided.

Rheumatic Heart Disease And Risk Of Incident Heart Failure Among Community-Dwelling Older Adults: A Prospective Cohort Study, Marjan Mujib, Ravi Desai, Mustafa Ahmed, Jason Guichard, Margaret Feller, O Ekundayo, Prakash Deedwania, Mahboob Ali, Inmaculada Aban, Thomas Love, Michel White, Wilbert Aronow, Shahbudin Rahimtoola, Robert Bonow, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Coronary Artery Disease, Coronary Revascularization, And Outcomes In Chronic Advanced Systolic Heart Failure, Mihai Gheorghiade, James Flaherty, Gregg Fonarow, Ravi Desai, Richard Lee, David Mcgiffin, Thomas Love, Inmaculada Aban, Eric Eichhorn, Robert Bonow, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Right Ventricular Ejection Fraction < 20% Is An Independent Predictor Of Mortality But Not Of Hospitalization In Older Systolic Heart Failure Patients, Philippe Meyer, Ravi Desai, Marjan Mujib, Margaret Feller, Chris Adamopoulos, Maciej Banach, Mitja Lainscak, Inmaculada Aban, Michel White, Wilbert Aronow, Prakash Deedwania, Ami Iskandrian, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Relationship Between Left And Right Ventricular Ejection Fractions In Chronic Advanced Systolic Heart Failure: Insights From The Best Trial, Ravi Desai, Philippe Meyer, Mustafa Ahmed, Marjan Mujib, Chris Adamopoulos, Michel White, Inmaculada Aban, Ami Iskandrian, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Design And Rationale Of Studies Of Neurohormonal Blockade And Outcomes In Diastolic Heart Failure Using Optimize-Hf Registry Linked To Medicare Data, Yan Zhang, Meredith Kilgore, Tarun Arora, Marjan Mujib, O. Ekundayo, Inmaculada Aban, Margaret Feller, Ravi Desai, Thomas Love, Richard Allman, Gregg Fonarow, Ali Ahmed

Ravi V Desai MD

No abstract provided.

Relation Of Torsion And Myocardial Strains To Lv Ejection Fraction In Hypertension, Mustafa Ahmed, Ravi Desai, Krishna Gaddam, Bharath Venkatesh, Shilpi Agarwal, Seidu Inusah, Steven Lloyd, Thomas Denney, David Calhoun, Louis Dell'italia, Himanshu Gupta

Ravi V Desai MD

No abstract provided.