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Full-Text Articles in Medicine and Health Sciences

Cobalt Use And Regulation In Horseracing: A Review, K. Brewer, G. Maylin, C. K. Fenger, Thomas Tobin Jan 2016

Cobalt Use And Regulation In Horseracing: A Review, K. Brewer, G. Maylin, C. K. Fenger, Thomas Tobin

Veterinary Science Faculty Publications

Cobalt, atomic weight 58.9, is a metallic element and environmental substance found in the animal in microgram quantities, predominantly as vitamin B12, but is also a component of at least one mammalian enzyme unassociated with B12. Cobalt is a required trace mineral and has long been administered as a dietary supplement to humans and animals. Cobalt deficiency outside of its requirement in vitamin B12 has not been reported in humans. The administration of cobalt salts was once standard treatment for anaemia in humans, owing to its ability to stimulate red blood cell synthesis. Elemental cobalt acts by stabilising hypoxia inducible …


Absorption And Utilization Of Choline And Vitamin B12 In Lactating Dairy Cows Using Different Delivery Methods, Virginia Maria Artegoitia Etcheverry Dec 2014

Absorption And Utilization Of Choline And Vitamin B12 In Lactating Dairy Cows Using Different Delivery Methods, Virginia Maria Artegoitia Etcheverry

Doctoral Dissertations

Choline and vitamin B12 are essential nutrients for growth and performances of production animals. However, both nutrients are extensively degraded during digestion in the rumen. This thesis comprised three experiments. First, four cows equipped with a rumen cannula and catheters in the portal vein and a mesenteric artery received a post-ruminal bolus of: 1) cyanocobalamin (CN-CBL) alone (0.1 g) [gram], 2) CN-CBL (0.1 g) + casein (10 g) or 3) CN-CBL (0.1 g) + whey proteins (10 g). After the bolus, blood samples were taken until 24 h [hour] post-bolus. The intestinal absorption of CN-CBL was greater when the vitamin …


Effeciency Of Various Supportive Treatments As A Cure For Anaemia In Cattle With Theileriosis, Nuri Altug, Nazmi Yüksek, Ihsan Keles, Cumali Özkan, Ibrahim Hakkı Yörük, Sezai Arslan Sep 2014

Effeciency Of Various Supportive Treatments As A Cure For Anaemia In Cattle With Theileriosis, Nuri Altug, Nazmi Yüksek, Ihsan Keles, Cumali Özkan, Ibrahim Hakkı Yörük, Sezai Arslan

The Thai Journal of Veterinary Medicine

The purpose of this study was to investigate the efficiency of various supportive treatments on the restoration of anaemia in theileriosis. A total of 20 cattle infected with theileriosis received intramuscularly a single dose of buparvaquone (2.5 mg/kg-1 bw) and were divided into 4 equal groups according to the different therapy options: whereas no supportive treatment was applied in group 1, administrations of vitamin B complex, antioxidant vitamins (A, D, E and C), minerals and trace elements were performed in groups 2, 3 and 4, respectively. Haematological parameters, serum concentrations of antioxidant vitamins, minerals and trace elements as well as …


A Critical Evaluation Of Serum Methylmalonic Acid And Vitamin B12 For The Assessment Of Cobalt Deficiency Of Growing Lambs In New Zealand, Tini Gruner, J Sedcole, J Furlong, A Sykes Apr 2009

A Critical Evaluation Of Serum Methylmalonic Acid And Vitamin B12 For The Assessment Of Cobalt Deficiency Of Growing Lambs In New Zealand, Tini Gruner, J Sedcole, J Furlong, A Sykes

Dr Tini M Gruner

AIM: To derive reference ranges for serum methylmalonic acid (MMA) for the diagnosis of cobalt/vitamin B12-responsiveness in lambs and critique existing serum vitamin B12 reference ranges. METHODS: Individual animal data from earlier supplementation trials, involving 225 ewes, 106 suckling lambs, 301 lambs during the suckling and post-weaning periods and 414 weaned lambs, for which weight gain to supplementation was observed, were used to derive relationships between serum vitamin B12 and MMA, and liveweight gain. RESULTS: Serum MMA concentrations were rarely elevated above the norm of <2 >μmol/L when serum vitamin B12 concentrations were >375 pmol/L, and not elevated into the range …