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Full-Text Articles in Medicine and Health Sciences

A Case Report Of Ulcerative Lymphangitis (A Mini Review Of Causes And Current Therapies), Fereydon Rezazadeh Zavoshti, Amir Babak Sioofy-Khojine, Hassan Ali Mahpeikar Jan 2009

A Case Report Of Ulcerative Lymphangitis (A Mini Review Of Causes And Current Therapies), Fereydon Rezazadeh Zavoshti, Amir Babak Sioofy-Khojine, Hassan Ali Mahpeikar

Turkish Journal of Veterinary & Animal Sciences

Ulcerative lymphangitis, or pigeon fever, is a bacterial infection of the lymphatic vessels of the skin in horses, cattle, sheep, and goats. Corynebacterium pseudotuberculosis is the classical cause of the disease. However, other pathogens such as Staphylococcus aureus have been isolated from cases of ulcerative lymphangitis. The aim of this report is to review the causes of pyoderma and skin abscesses in horses with specific attention to Staphylococcus aureus. A 10-year-old Thoroughbred stallion was examined in the suburbs of Tabriz (northwest of Iran) in February 2007. Skin abscesses were present around the hock joints on the hind limbs, on the …


Matrix Metalloproteinases In The Equine Systemic Inflammatory Response: Implications For Equine Laminitis, Lee Ann Fugler Jan 2009

Matrix Metalloproteinases In The Equine Systemic Inflammatory Response: Implications For Equine Laminitis, Lee Ann Fugler

LSU Doctoral Dissertations

Laminitis is a crippling and often life-threatening disease of the equine foot. Soft tissue damage characteristic of this disease has been associated with increased MMP activity. Therefore, it seems likely that MMPIs could be potential therapeutic agents for laminitis. Further characterization of equine MMPs and evaluation of the effectiveness of MMPIs in the horse are needed. Equine MMP-9 was harvested from neutrophils, purified by affinity chromatography, and evaluated using western blotting and gelatin zymography. The Biotrak MMP-9 Activity Assay was evaluated for use with equine samples using equine neutrophil MMP-9 as a standard, and was determined to have insufficient sensitivity …


Effects Of Clenbuterol On Skeletal And Cardiac Muscle In Horses, Jessica Thompson Jan 2009

Effects Of Clenbuterol On Skeletal And Cardiac Muscle In Horses, Jessica Thompson

LSU Master's Theses

Clenbuterol is a commonly prescribed β2-adrenergic agonist approved for veterinary use as a bronchodilator in horses with reactive and obstructive airway disease. Potential for abuse of this drug in the horse industry is substantial, due to the perceptions that clenbuterol increases performance and lean muscle mass. Although anabolic effects have been confirmed in multiple species, recent studies into the effects of clenbuterol in exercising horses suggest that clenbuterol doses within therapeutic ranges negatively impact aerobic capacity and cardiac function. Results of studies in murine models demonstrate that clenbuterol directly induces skeletal and cardiac muscle cell death at high doses. Three …