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Proliferation And Apoptosis Of The Bitch Ovary During The Different Stages Of The Oestrous Cycle, Sayamon Srisuwatanasagul, Sukanya Manee-In, Promporn Raksaseri, Kongkiat Srisuwatanasagul Sep 2009

Proliferation And Apoptosis Of The Bitch Ovary During The Different Stages Of The Oestrous Cycle, Sayamon Srisuwatanasagul, Sukanya Manee-In, Promporn Raksaseri, Kongkiat Srisuwatanasagul

The Thai Journal of Veterinary Medicine

In order to maintain homeostasis of the ovary, proliferation and apoptosis occur simultaneously in different ovarian cell types. It was shown that steroid hormone which changed during the oestrous cycle, may regulate these mechanisms in normal mammal ovarian tissues. Therefore, the present study was aimed to study cell proliferation and apoptosis during different stages of the oestrous cycle in the bitch ovary by using immunohistochemistry and TUNEL assay. The bitch ovaries were collected at 4 different stages of the oestrous cycle, which were prooestrus, oestrus, dioestrus and anoestrus. Immunohistochemistry and TUNEL assay were applied to detect Ki-67 protein and apoptosis …


Effects Of Clenbuterol On Skeletal And Cardiac Muscle In Horses, Jessica Thompson Jan 2009

Effects Of Clenbuterol On Skeletal And Cardiac Muscle In Horses, Jessica Thompson

LSU Master's Theses

Clenbuterol is a commonly prescribed β2-adrenergic agonist approved for veterinary use as a bronchodilator in horses with reactive and obstructive airway disease. Potential for abuse of this drug in the horse industry is substantial, due to the perceptions that clenbuterol increases performance and lean muscle mass. Although anabolic effects have been confirmed in multiple species, recent studies into the effects of clenbuterol in exercising horses suggest that clenbuterol doses within therapeutic ranges negatively impact aerobic capacity and cardiac function. Results of studies in murine models demonstrate that clenbuterol directly induces skeletal and cardiac muscle cell death at high doses. Three …