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West Nile Virus Blood Transfusion-Related Infection Despite Nucleic Acid Testing, Alexandre Macedo De Oliveira, Brady Beecham, Susan P. Montgomery, Robert S. Lanciotti, Jeffrey M. Linnen, Cristina Giachetti, Larry A. Pietrelli, Susan L. Stramer, Thomas J. Safranek Dec 2004

West Nile Virus Blood Transfusion-Related Infection Despite Nucleic Acid Testing, Alexandre Macedo De Oliveira, Brady Beecham, Susan P. Montgomery, Robert S. Lanciotti, Jeffrey M. Linnen, Cristina Giachetti, Larry A. Pietrelli, Susan L. Stramer, Thomas J. Safranek

Other Publications in Zoonotics and Wildlife Disease

BACKGROUND: A case of West Nile virus (WNV) encephalitis associated with transfusion of blood that did not react when tested for WNV by minipool (MP) nucleic acid testing (NAT) is described. A Nebraska man developed clinical encephalitis 13 days after surgery and transfusion of 26 blood components. Antibody testing confirmed WNV infection. An investigation was initiated to determine the source of this infection.

STUDY DESIGN AND METHODS: The patient’s family members were interviewed to identify risk factors for WNV infection. Residual samples were retested for WNV RNA using transcription-mediated amplification (TMA) assay and two polymerase chain reaction (PCR) assays. Blood …


Investigation Of The Transmission Of Mycobacterium Bovis From Deer To Cattle Through Indirect Contact, Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple Nov 2004

Investigation Of The Transmission Of Mycobacterium Bovis From Deer To Cattle Through Indirect Contact, Mitchell V. Palmer, W. Ray Waters, Diana L. Whipple

Michigan Bovine Tuberculosis Bibliography and Database

Objective—To investigate the infection of calves with Mycobacterium bovis through oral exposure and transmission of M bovis from experimentally infected white-tailed deer to uninfected cattle through indirect contact.

Animals—24 11-month-old, white-tailed deer and 28 6-month-old, crossbred calves.

Procedure—In the oral exposure experiment, doses of 4.3 X 106 CFUs (high dose) or 5 X 103 CFUs (low dose) of M bovis were each administered orally to 4 calves; as positive controls, 2 calves received M bovis (1.7 X 105 CFUs) via tonsillar instillation. Calves were euthanatized and examined 133 days after exposure. Deer-to-cattle transmission was …


Identification Of Common Subpopulations Of Non-Sorbitol-Fermenting, Β-Glucuronidase-Negative Escherichia Coli O157:H7 From Bovine Production Environments And Human Clinical Samples, Zhijie Yang, Joy Kovar, Jaehyoung Kim, Joseph Nietfeldt, David R. Smith, Rodney A. Moxley, Michael E. Olson, Paul D. Fey, Andrew K. Benson Nov 2004

Identification Of Common Subpopulations Of Non-Sorbitol-Fermenting, Β-Glucuronidase-Negative Escherichia Coli O157:H7 From Bovine Production Environments And Human Clinical Samples, Zhijie Yang, Joy Kovar, Jaehyoung Kim, Joseph Nietfeldt, David R. Smith, Rodney A. Moxley, Michael E. Olson, Paul D. Fey, Andrew K. Benson

School of Veterinary and Biomedical Sciences: Faculty Publications

Non-sorbitol-fermenting, β-glucuronidase-negative Escherichia coli O157:H7 strains are regarded as a clone complex, and populations from different geographical locations are believed to share a recent common ancestor. Despite their relatedness, high-resolution genotyping methods can detect significant genome variation among different populations. Phylogenetic analysis of high-resolution genotyping data from these strains has shown that subpopulations from geographically unlinked continents can be divided into two primary phylogenetic lineages, termed lineage I and lineage II, and limited studies of the distribution of these lineages suggest there could be differences in their propensity to cause disease in humans or to be transmitted to humans. Because …


Seasonality Of Tuberculosis In India: Is It Real And What Does It Tell Us?, Lorna E. Thorpe, Thomas R. Frieden, Kayla F. Laserson, Charles Wells, Gulshan Khatri Oct 2004

Seasonality Of Tuberculosis In India: Is It Real And What Does It Tell Us?, Lorna E. Thorpe, Thomas R. Frieden, Kayla F. Laserson, Charles Wells, Gulshan Khatri

Michigan Bovine Tuberculosis Bibliography and Database

India has a third of the world’s tuberculosis cases. Large-scale expansion of a national program in 1998 has allowed for population-based analyses of data from tuberculosis registries. We assessed seasonal trends using quarterly reports from districts with stable tuberculosis control programs (population 115 million). In northern India, tuberculosis diagnoses peaked between April and June, and reached a nadir between October and December, whereas no seasonality was reported in the south. Overall, rates of new smear-positive tuberculosis cases were 57 per 100 000 population in peak seasons versus 46 per 100 000 in trough seasons. General health-seeking behavior artifact was ruled …


Cytokines And Synthetic Double-Stranded Rna Augment The T Helper 1 Immune Response Of Swine To Porcine Reproductive And Respiratory Syndrome Virus, William A. Meier, Robert J. Husmann, William M. Schnitzlein, Fernando A. Osorio, Joan K. Lunney, Federico A. Zuckermann Oct 2004

Cytokines And Synthetic Double-Stranded Rna Augment The T Helper 1 Immune Response Of Swine To Porcine Reproductive And Respiratory Syndrome Virus, William A. Meier, Robert J. Husmann, William M. Schnitzlein, Fernando A. Osorio, Joan K. Lunney, Federico A. Zuckermann

School of Veterinary and Biomedical Sciences: Faculty Publications

Immunization of pigs with a modified live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine initially elicits a weak interferon (IFN)-γ response. To improve the immune response, an adjuvant consisting of plasmid encoding either porcine interleukin (IL)-12 or IFN-α was co-administered during vaccination. In the presence of either adjuvant, at least a threefold increase in the primary virus-specific IFN-γ response was observed. While this enhancement was only transient (1 week) when the IL-12 expressing plasmid was used, the effect was not only still apparent at 6 weeks after vaccination in the presence of the IFN-α expressing plasmid but even after …


Johne’S Disease, Inflammatory Bowel Disease, And Mycobacterium Paratuberculosis, Ofelia Barletta-Chacon, Luiz E. Bermudez, Raúl G. Barletta Oct 2004

Johne’S Disease, Inflammatory Bowel Disease, And Mycobacterium Paratuberculosis, Ofelia Barletta-Chacon, Luiz E. Bermudez, Raúl G. Barletta

School of Veterinary and Biomedical Sciences: Faculty Publications

Johne’s disease is a chronic diarrhea affecting all ruminants. Mycobacterium avium subsp. paratuberculosis (MAP), a slowly growing mycobacteria, is the etiologic agent. There is also a concern that MAP might be a causative agent of some cases of inflammatory bowel disease in humans, especially Crohn’s disease. Food products including pasteurized bovine milk have been suggested as potential sources of human infection. This review addresses microbial factors that may contribute to its pathogenicity. In addition, the experimental evidence defining MAP as the cause of Johne’s disease and the issues and controversies surrounding its potential pathogenic role in humans are discussed.


Waccnes Containing Bovine Herpe Svirus 1 Attenuated By Mutation In Latency-Related Gene, Clinton J. Jones Sep 2004

Waccnes Containing Bovine Herpe Svirus 1 Attenuated By Mutation In Latency-Related Gene, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Vaccines for pathogenic Strains of bovine herpesvirus 1 (BHV-1) which are based on attenuated BHV-1 having a mutation in the latency-related gene are provided. Live, attenuated vaccines are also provided which express anti gens from other viral or bacterial pathogens and thus form the basis of a variety of vaccines.


West Nile Virus Infection In Reindeer (Rangifer Tarandus), Mitchell V. Palmer, William C. Stoffregen, Douglas G. Rogers, Amir N. Hamir, Juergen A. Richt, Douglas D. Pedersen, W. Ray Waters Sep 2004

West Nile Virus Infection In Reindeer (Rangifer Tarandus), Mitchell V. Palmer, William C. Stoffregen, Douglas G. Rogers, Amir N. Hamir, Juergen A. Richt, Douglas D. Pedersen, W. Ray Waters

School of Veterinary and Biomedical Sciences: Faculty Publications

West Nile virus (WNV) infection in 4 reindeer (Rangifer tarandus) resulted in lymphohistiocytic encephalomyelitis within the medulla oblongata and cervical spinal cord. Immunohistochemistry revealed WNV antigen within neurons and among mononuclear cell infiltrates. These represent the first known cases of clinical WNV infection in Cervidae. Clinical signs and lesions were similar to those described in horses. Nucleotide sequence of a 768-bp region of the WNV E-glycoprotein gene revealed 1 nucleotide mutation, which resulted in a single amino acid substitution from a serine to a glycine (position 227 of E-glycoprotein) when compared with the prototype WNV-NY99 strain (isolated from …


Bovine Tuberculosis In Michigan White-Tailed Deer Aug 2004

Bovine Tuberculosis In Michigan White-Tailed Deer

Other Publications in Zoonotics and Wildlife Disease

Starting in 1995 hunter harvested, road killed, and other dead deer were examined for bovine TB infection. White-tailed deer in Michigan have since been tested year round for bovine TB. Testing revealed that most of the TB positive animals were located in a core area in the northeastern part of Michigan's Lower Peninsula. The core area is located around the four corners where the counties of Montmorency, Alpena, Oscoda and Alcona meet. Antrim, Crawford, Emmet, Iosco, Mecosta, Osceola, Otsego, Presque Isle, and Roscommon Counties have also had animals test positive for bovine TB.

In the U.S. today, the threat of …


Salmonella In Songbirds Jul 2004

Salmonella In Songbirds

Other Publications in Zoonotics and Wildlife Disease

Salmonella is a type of bacterium found in the gut of many species of birds both domestic and wild. During periods of stress it can cause outbreaks of sickness and death. Its importance in songbird populations generally and the occurrence of outbreaks in this province specifically are discussed in this fact sheet.


Parasites Of Caribou (1): Brain Worm Infestation Jul 2004

Parasites Of Caribou (1): Brain Worm Infestation

Other Publications in Zoonotics and Wildlife Disease

Brain worm is the common name for a disease of caribou that was first recognized in Central Newfoundland in the 1970's and has since been seen in other caribou herds including most recently the caribou of the Southern Avalon. Its more scientific name is Cerebrospinal Elaphostrongylosis (CSE) and is caused by the nematode Elaphostrongylus rangiferi.
Infection can cause severe illness and death in affected animals and has a particularly strong impact on herds that have not been previously exposed to this parasite.
As this is primarily a disease of caribou, there is no direct public health threat to humans. Moose …


Parasites Of Caribou (3): Tapeworm Cysts Jul 2004

Parasites Of Caribou (3): Tapeworm Cysts

Other Publications in Zoonotics and Wildlife Disease

All wild animals carry diseases. In some cases these might be of concern if they can spread to humans or domestic animals. In other cases, they might be of interest if they impact on the health of our wild herds, or simply if they have been noticed by hunters and you would like to know more.
This fact sheet is one of a series produced on the common diseases of caribou and covers the cyst form of three common tapeworms. Two (Taenia hydatigena and Taenia krabbei) exist on both the island of Newfoundland and in Labrador, while the …


Pesticide Poisoning Of Seagulls Jul 2004

Pesticide Poisoning Of Seagulls

Other Publications in Zoonotics and Wildlife Disease

In April 2000 a major pesticide leak caused the death and illness of a significant number of wild birds. The findings and conclusions of this die-off are detailed.


Parasites Of Caribou (2): Fly Larvae Infestations Jul 2004

Parasites Of Caribou (2): Fly Larvae Infestations

Other Publications in Zoonotics and Wildlife Disease

All wild animals carry diseases. In some cases these might be of concern if they can spread to humans or domestic animals. In other cases they might be of interest if they impact on the health of our wild herds, or simply because the signs of the disease have been noticed and you want to know more.
This fact sheet is one of a series produced on the common diseases of caribou and covers the larval form of two different flies commonly seen in this province. Neither of these are a cause of public health concern.


Parasites Of The Snowshoe Hare (1): Tapeworm Cysts Jul 2004

Parasites Of The Snowshoe Hare (1): Tapeworm Cysts

Other Publications in Zoonotics and Wildlife Disease

All wild animals carry diseases. In some cases these might be of concern because they can spread to humans or domestic animals. In other cases they may be of interest simply because the signs of the disease have been seen and you want to know more. Though diseases are relatively common in these animals there is usually an increase in reporting when the hare populations are at a peak. High populations mean that there is an increased chance of one animal infecting another. In addition, when there are too many animals in one area, the amount of available food is …


Keep Your Cabin Free Of Rodents Jul 2004

Keep Your Cabin Free Of Rodents

Other Publications in Zoonotics and Wildlife Disease

Cabins that have been closed for the winter can become nesting sites for mice, shrews and other rodents. These animals can carry fleas, ticks, viruses or other organisms on their skin, in their droppings or urine. These can cause diseases in humans, especially when you breathe in the dust from their droppings or nesting sites.
Avoid close contact with rodent urine, droppings, nesting materials or with any food or surfaces contaminated with them.
Always wear rubber gloves when handling dead rodents, or when cleaning traps, droppings, nesting sites or other areas that rodents may have visited.


Lyme Disease In Newfoundland Jul 2004

Lyme Disease In Newfoundland

Other Publications in Zoonotics and Wildlife Disease

Lyme Disease, spread by ticks, is an illness affecting both humans and domestic animals. The presence of the bacteria causing this illness was reported for the first time in this province in July 2001. This fact sheet provides details on the disease and its spread.


Relative Importance Of Heat-Labile Enterotoxin In The Causation Of Severe Diarrheal Disease In The Gnotobiotic Piglet Model By A Strain Of Enterotoxigenic Escherichia Coli That Produces Multiple Enterotoxins, Emil M. Berberov, You Zhou, David H. Francis, Michael A. Scott, Stephen D. Kachman, Rodney A. Moxley Jul 2004

Relative Importance Of Heat-Labile Enterotoxin In The Causation Of Severe Diarrheal Disease In The Gnotobiotic Piglet Model By A Strain Of Enterotoxigenic Escherichia Coli That Produces Multiple Enterotoxins, Emil M. Berberov, You Zhou, David H. Francis, Michael A. Scott, Stephen D. Kachman, Rodney A. Moxley

School of Veterinary and Biomedical Sciences: Faculty Publications

Enterotoxigenic Escherichia coli (ETEC) strains that produce multiple enterotoxins are important causes of severe dehydrating diarrhea in human beings and animals, but the relative importance of these enterotoxins in the pathogenesis is poorly understood. Gnotobiotic piglets were used to study the importance of heat-labile enterotoxin (LT) in infection with an ETEC strain that produces multiple enterotoxins. LT-eltAB) and complemented mutants of an F4+ LT+ STb+ EAST1+ ETEC strain were constructed, and the virulence of these strains was compared in gnotobiotic piglets expressing receptors for F4+ fimbria. Sixty percent of the piglets …


Hantavirus In Deer Mice Jun 2004

Hantavirus In Deer Mice

Other Publications in Zoonotics and Wildlife Disease

Hantaviruses are a group of viruses recently identified in North America as being a risk for human health. The importance of these viruses and the facts on their presence in Newfoundland are discussed.


Ileocolitis Associated With Anaerobiospirillum In Cats, H. E. V. De Cock, S. L. Marks, B. A. Stacy, T. S. Zabka, J. Burkitt, G. Lu, David J. Steffen, Gerald E. Duhamel Jun 2004

Ileocolitis Associated With Anaerobiospirillum In Cats, H. E. V. De Cock, S. L. Marks, B. A. Stacy, T. S. Zabka, J. Burkitt, G. Lu, David J. Steffen, Gerald E. Duhamel

School of Veterinary and Biomedical Sciences: Faculty Publications

Ileocolitis associated with spiral bacteria identified as an Anaerobiospirillum sp. was found in six cats. Two cats had acute onset of gastrointestinal signs characterized by vomiting and diarrhea in one cat and vomiting in another cat, one cat had chronic diarrhea that was refractory to medical therapy; one cat had acute onset of anorexia and lethargy, and two cats had clinical signs that were not related to the gastrointestinal tract. The presence of an Anaerobiospirillum sp. was demonstrated on the basis of ultrastructural morphology of spiral bacteria associated with intestinal lesions and PCR amplification of a genus-specific 16S rRNA gene …


Michigan Bovine Tuberculosis Eradication Project: 2004 Activities Report And Conference Proceedings Jun 2004

Michigan Bovine Tuberculosis Eradication Project: 2004 Activities Report And Conference Proceedings

Michigan Bovine Tuberculosis Bibliography and Database

On June 9 and 10, 2004, the State of Michigan and U.S. Department of Agriculture hosted the eighth annual Bovine Tuberculosis (TB) Conference, with guest speakers from Georgia, Colorado, Iowa, New York and two Canadian provinces. Our guests came together from across North America to receive policy updates and share the latest scientific data and innovative research on bovine TB.

Among other things, the speakers shared insight on: the promotion of biosecurity; the $30 million annual costs of TB eradication in New Zealand; the latest research in new and improved blood tests; and the first season results of the Michigan …


Rabies In Newfoundland & Labrador May 2004

Rabies In Newfoundland & Labrador

Other Publications in Zoonotics and Wildlife Disease

Rabies is a deadly viral disease of the brain spread by the bite of infected mammals. It is most commonly seen in red or arctic foxes in this province though other wild animals such as bats may carry the disease. Sick foxes can bite other foxes, dogs, cats, wolves, caribou, other animals and people and make them sick. Once bitten by an animal with rabies it can take from two weeks to six months before the animal shows signs of the disease. Though uncommon, this period can be as short as 4 days or as long as a year or …


Identification Of A Novel Bovine Herpesvirus 1 Transcript Containing A Small Open Reading Frame That Is Expressed In Trigeminal Ganglia Of Latently Infected Cattle, Melissa Inman, Joe Zhou, Heather Webb, Clinton J. Jones May 2004

Identification Of A Novel Bovine Herpesvirus 1 Transcript Containing A Small Open Reading Frame That Is Expressed In Trigeminal Ganglia Of Latently Infected Cattle, Melissa Inman, Joe Zhou, Heather Webb, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

Bovine herpesvirus 1 (BHV-1), like other Alphaherpesvirinae subfamily members, establishes latency in sensory neurons. The latency-related (LR) RNA is abundantly expressed during latency, and expression of an LR protein is required for the latency reactivation cycle in cattle. Within LR promoter sequences, a 135-aminoacid open reading frame (ORF) was identified, ORF-E, that is antisense to the LR RNA. ORF-E is also downstream of the gene encoding the major viral transcriptional activator, bICP0. Strand-specific reverse transcription-PCR demonstrated that a transcript containing ORF-E was consistently expressed in trigeminal ganglia (TG) of latently infected calves, productively infected cultured cells, and acutely infected calves. …


“French Heartworm” Infection Of Dogs & Foxes In Newfoundland Apr 2004

“French Heartworm” Infection Of Dogs & Foxes In Newfoundland

Other Publications in Zoonotics and Wildlife Disease

French Heartworm is the common name for a parasitic disease affecting foxes, dogs, and other members of the dog family. Caused by the nematode (worm) Angiostrongylus vasorum, this disease was first thought to exist in France in the mid 1800's. It is now considered to exist generally in Europe but has not been reported in North America other than on the Island of Newfoundland, with the exception of infected animals imported from Europe but diagnosed in North America. The first case recorded in Newfoundland was in Aquaforte (Avalon Peninsula) in 1973.
When and how it might have come over …


Seroprevalence Of Bartonella Infection In American Free-Ranging And Captive Pumas (Felis Concolor) And Bobcats (Lynx Rufus), Bruno B. Chomel, Yoko Kikuchi, Janice S. Martenson, Melodie E. Roelke-Parker, Chao-Chin Chang, Rickie W. Kasten, Janet E. Foley, John Laudre, Kerry Murphy, Pamela K. Swift, Vicki L. Kramer, Stephen J. O'Brien Apr 2004

Seroprevalence Of Bartonella Infection In American Free-Ranging And Captive Pumas (Felis Concolor) And Bobcats (Lynx Rufus), Bruno B. Chomel, Yoko Kikuchi, Janice S. Martenson, Melodie E. Roelke-Parker, Chao-Chin Chang, Rickie W. Kasten, Janet E. Foley, John Laudre, Kerry Murphy, Pamela K. Swift, Vicki L. Kramer, Stephen J. O'Brien

Other Publications in Zoonotics and Wildlife Disease

Bartonella henselae is the main agent of cat scratch disease in humans and domestic cats are the main reservoir of this bacterium. We conducted a serosurvey to investigate the role of American wild felids as a potential reservoir of Bartonella species. A total of 479 samples (439 serum samples and 40 Nobuto strips) collected between 1984 and 1999 from pumas (Felis concolor) and 91 samples (58 serum samples and 33 Nobuto strips) collected from bobcats (Lynx rufus) in North America, Central America and South America were screened for B. henselae antibodies. The overall prevalence of B. …


Chronic Wasting Disease—Prion Disease In The Wild, Steve Bunk Apr 2004

Chronic Wasting Disease—Prion Disease In The Wild, Steve Bunk

Other Publications in Zoonotics and Wildlife Disease

In 1967, mule deer in a research facility near Fort Collins, Colorado, in the United States apparently began to react badly to their captivity. At least, that was the guess of researchers working on the natural history and nutrition of the deer, which became listless and showed signs of depressed mood, hanging their heads and lowering their ears. They lost appetite and weight. Then they died—of emaciation, pneumonia, and other complications—or were euthanized. The scientists dubbed it chronic wasting disease (CWD), and for years they thought it might be caused by stress, nutritional deficiencies, or poisoning. A decade later, CWD …


A Mutation In The Latency-Related Gene Of Bovine Herpesvirus 1 Inhibits Protein Expression From Open Reading Frame 2 And An Adjacent Reading Frame During Productive Infection, Yanjun Jiang, Melissa Inman, Yange Zhang, Nuria Aleman Posadas, Clinton J. Jones Mar 2004

A Mutation In The Latency-Related Gene Of Bovine Herpesvirus 1 Inhibits Protein Expression From Open Reading Frame 2 And An Adjacent Reading Frame During Productive Infection, Yanjun Jiang, Melissa Inman, Yange Zhang, Nuria Aleman Posadas, Clinton J. Jones

School of Veterinary and Biomedical Sciences: Faculty Publications

The latency-related (LR) gene of bovine herpesvirus 1 (BHV-1) is abundantly expressed during latency. A mutant BHV-1 strain that contains three stop codons at the 5′ terminus of the LR gene (LR mutant) does not reactivate from latency. This study demonstrates that the LR mutant does not express open reading frame 2 or an adjacent reading frame that lacks an initiating ATG (reading frame C). Since the LR mutant and wild-type BHV-1 express similar levels of LR RNA, we conclude that LR protein expression plays an important role in regulating the latency reactivation cycle in cattle.


Tuberculosis, John B. Kaneene, Charles O. Thoen Mar 2004

Tuberculosis, John B. Kaneene, Charles O. Thoen

Michigan Bovine Tuberculosis Bibliography and Database

Tuberculosis is a term that encompasses various diseases caused by bacteria of the Mycobacterium tuberculosis complex, including M tuberculosis, M bovis, M africanum, and other mycobacterial species. Whereas M tuberculosis infection is largely spread from human to human, M bovis infection has been identified as a zoonotic disease with most cases of human infection attributable to animal sources. The mycobacteria other than tuberculosis complex (MOTT), which includes M avium subsp avium and M avium subsp intracellulare isolated from animals, has been isolated from immune-compromised humans (ie, those with human immunodeficiency virus [HIV] infection), but seldom from immunocompetent humans. Recently, …


Escherichia Coli 0 1 57:H7: An Update On Intestinal Colonization And Virulence Mechanisms, Rodney A. Moxley Mar 2004

Escherichia Coli 0 1 57:H7: An Update On Intestinal Colonization And Virulence Mechanisms, Rodney A. Moxley

School of Veterinary and Biomedical Sciences: Faculty Publications

Cattle are a major reservoir of Escherichia coli 0157:H7, an important zoonotic pathogen that causes hemorrhagic colitis and hemolytic uremic syndrome (HUS). Colonization of cattle occurs predominantly in the large intestine, and may especially target follicle-associated epithelium (FAE) in the terminal rectum. Bacterial colonization involves induction of attaching- effacing (A/E) lesions, mediated by type III secreted proteins and an outer membrane protein called intimin. ToxB, encoded on plasmid p0157, contributes to adherence of E. coli 0157:H7 through promotion of the production and/or secretion of type III secreted proteins. Introduction of type III secreted proteins and intestinal colonization appear to involve …


Chronic Wasting Disease Management In Nebraska Jan 2004

Chronic Wasting Disease Management In Nebraska

Other Publications in Zoonotics and Wildlife Disease

The presence of Chronic Wasting Disease (CWD) in free-roaming and domesticated cervine animal populations of deer and elk in the state of Nebraska presents a threat to the natural resources of the state. The presence of this disease could drastically restrict the successful achievement of the goals and objectives of the Nebraska Game and Parks Commission (NGPC) as set forth in their long range plan “Focusing on the Future…A Plan for Nebraska’s Fish, Wildlife and Parkland Resources”. Objective 3 in the Big Game section of this plan is to “Monitor the status and health of deer, so reasonable assumptions may …