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Full-Text Articles in Medicine and Health Sciences

Canine Extraskeletal Osteosarcoma Of The Salivary Gland, Theerayuth Kaewamatawong, Anudep Rungsipipat, Suwicha Chutatep Jun 2000

Canine Extraskeletal Osteosarcoma Of The Salivary Gland, Theerayuth Kaewamatawong, Anudep Rungsipipat, Suwicha Chutatep

The Thai Journal of Veterinary Medicine

An 8 year-old male mongrel dog and 12 year-old male German Shepherd had a 10 x 10 cm mass and 15 x 10 cm mass located in the mandibular region. The encapsulated firm white masses had multiple cysticlike nodules filled with mucous. Histopathology revealed clusters of pleomorphic, large, round to oval shaped cells, irregular ovoid to spindle nuclei with highly mitotic figures that showed osteoid and bony formation. The neoplastic cells were immunoreactive in some parts for vimentin and cytokeratin but not for desmin, α-SMA and S-100 protein. Hyperplastic salivary gland cells were also present. Electron microscopy revealed prominent nucleoli …


Molecular Cloning, Characterization And Expression Of A Novel Retinal Clusterin-Like Protein Cdna, Qi Zhang, Kunal Ray, Gregory M. Acland, Jill M. Czarnecki, Gustavo D. Aguirre Jan 2000

Molecular Cloning, Characterization And Expression Of A Novel Retinal Clusterin-Like Protein Cdna, Qi Zhang, Kunal Ray, Gregory M. Acland, Jill M. Czarnecki, Gustavo D. Aguirre

Gustavo D. Aguirre, VMD, PhD

A novel gene expressed predominantly in retina, but detected at a conspicuously lower level in retina of canine progressive rod cone degeneration (prcd), has been identified by suppression subtractive hybridization and retinal cDNA library screening. The characterized region of cDNA of the novel gene includes 1017 nucleotides of coding sequence predicted to encode a protein of 338 amino acids (Mr 39 389), 791 nucleotides of 5′-untranslated region (UTR), and 300 nucleotides of 3′-UTR including the poly(A)+ tail. Multiple transcripts were detected in retina by Northern blot analysis, and a lower level of expression was observed in …


Effects Of Isofluran On Cardiac Performance In Dogs With Experimental Acute Hemorrhagic, Utku Bakirel, Yücel Meral, Abdullah Kayar, Tarik Bi̇lal, Oktay Düzgün Jan 2000

Effects Of Isofluran On Cardiac Performance In Dogs With Experimental Acute Hemorrhagic, Utku Bakirel, Yücel Meral, Abdullah Kayar, Tarik Bi̇lal, Oktay Düzgün

Turkish Journal of Veterinary & Animal Sciences

The effects of isofluran on cardiac performance in dogs with experimental acute hemorrhagic anemia (AHA) were inves-tigated. A local anesthetic agent was administered to dogs in the control group (=2) and isofluran to dogs in the experimental group (n=6). Left ventricle systolic and diastolic blood pressure with filling and ejection time before and 15 min after AHA were deter-mined in all dogs. While left ventricle systolic blood pressure decreased (from 114±3 mm/Hg to 54±4 mm/Hg) and diastolic blood pressure decreased (from 88±6 mm/Hg to 40±2 mm/Hg), filling time increased (from 0.16±0.025 mm/sec to 0.40±0.065 mm/sec, p