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Full-Text Articles in Medicine and Health Sciences

Timp-1 Expression Is Increased In X-Linked Progressive Retinal Atrophy Despite Its Exclusion As A Candidate Gene, Caroline Zeiss, Gregory M. Acland, Gustavo D. Aguirre, Kunal Ray Dec 1998

Timp-1 Expression Is Increased In X-Linked Progressive Retinal Atrophy Despite Its Exclusion As A Candidate Gene, Caroline Zeiss, Gregory M. Acland, Gustavo D. Aguirre, Kunal Ray

Gustavo D. Aguirre, VMD, PhD

X-linked progressive retinal atrophy (XLPRA) is the only known natural animal model for X-linked retinitis pigmentosa (XLRP), a blinding disorder in man. The tissue inhibitor metalloproteinase 1 gene (TIMP-1), present in close proximity to one of the two XLRPloci, was tested as a candidate for XLPRA, by first characterizing the cDNA and gene from a normal dog. The cloned canine TIMP-1 cDNA is predicted to encode a protein of 207 amino acids with 66–83% identity in the deduced aa sequence with homologous mammalian genes. No sequence difference in the coding sequence of  …


Renal Adenoma In A Dog, Ayhan Atasever, Oğuz Kul Jan 1998

Renal Adenoma In A Dog, Ayhan Atasever, Oğuz Kul

Turkish Journal of Veterinary & Animal Sciences

A case of adenoma on the right kidney was described in a 17 years old, German Shepherd male dog. Macroscopically, Sclerotic kidney had a mass which was 0.4x0.8 cm in size and gray-white in colour. Microscopically, lesions showed typical morphology of renal adenoma.


A Case Of Alaria Alata In A Dog, Şinasi Umur Jan 1998

A Case Of Alaria Alata In A Dog, Şinasi Umur

Turkish Journal of Veterinary & Animal Sciences

One of the 20 necropsied stray dogs in Kars city was found naturally infected with three adults of Alaria alata (Goeze, 1782). This is the first report of A. alata from dogs in Turkey. The parasites were measured 2.34 (2.27-2.40) mm in length and 1.46 (1.43-1.50) mm in width.


Splenic Hemangiosarcoma With Abdominal Dissemination In A Dog, M. Yavuz Gülbahar, Tolga Güvenç, Ömer Beşalti Jan 1998

Splenic Hemangiosarcoma With Abdominal Dissemination In A Dog, M. Yavuz Gülbahar, Tolga Güvenç, Ömer Beşalti

Turkish Journal of Veterinary & Animal Sciences

A case of spontaneosly ruptured splenic hemangiosarcoma with abdominal dissemination in a 12-year-old male German shepherd dog is described. At necropsy, a ruptured tumor mass was seen in the ventral region of the visceral surface of the spleen, and disseminated tumor masses were seen throughout the peritoneal cavity. Histologically, in both the primary tumor mass and dis-seminated tumor masses, atypical endothelial cells lining vascular spaces as small clefts or as cavernous channels were observed. Some immunological properties of tumor cells were determined for endothelial cell markers (factor VII-related antigen=von Willebrand's factor [vWf] and CD31 antigen), mesenchymal tissue marker (vimentin) and …


Ventricular Fibrillation Induced By Thiopental Sodium During Anesthesia In A Dog, Zülfikar Saritaş, Perran Gökçe, Bahattin Koç Jan 1998

Ventricular Fibrillation Induced By Thiopental Sodium During Anesthesia In A Dog, Zülfikar Saritaş, Perran Gökçe, Bahattin Koç

Turkish Journal of Veterinary & Animal Sciences

In this case report, a sudden devoloped ventricular fibrillation following Pentothal anaesthesia in a dog and the treatment done was subjected. No abnormal findings were detected according to haemotologic and biochemical tests and ECG obtained at the preoperative period. Blood gases analysis and ECG monitoring were performed before anaesthesia induction for this experimental surgery. After the case was premedicated with Xylazine hydrochlorid (2mg/kg im), anaesthesia was induced by pentothal (Thiopental sodium 15 mg/kg iv). Following respiratoric depression, the dog was entubated and connected to the volume respiratory device. The dog was ventilated with 40% oxygene-air mixture 16 per minute. At …