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Medicine and Health Sciences Commons

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Veterinary Medicine

Selected Works

2015

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Full-Text Articles in Medicine and Health Sciences

Serum Cortisol Concentrations In Dogs With Pituitary-Dependent Hyperadrenocorticism And Atypical Hyperadrenocorticism, Linda Frank, George A. Henry, Jacqui C. Whittemore, B D. Enders, Dianne I. Mawby, Barton W. Rohrbach Jan 2015

Serum Cortisol Concentrations In Dogs With Pituitary-Dependent Hyperadrenocorticism And Atypical Hyperadrenocorticism, Linda Frank, George A. Henry, Jacqui C. Whittemore, B D. Enders, Dianne I. Mawby, Barton W. Rohrbach

Linda Frank MS, DVM, DACVD

BACKGROUND: Atypical hyperadrenocorticism (AHAC) is considered when dogs have clinical signs of hypercortisolemia with normal hyperadrenocorticism screening tests. HYPOTHESIS/OBJECTIVES: To compare cortisol concentrations and adrenal gland size among dogs with pituitary-dependent hyperadrenocorticism (PDH), atypical hyperadrenocorticism (AHAC), and healthy controls. ANIMALS: Ten healthy dogs, 7 dogs with PDH, and 8 dogs with AHAC. METHOD: Dogs were prospectively enrolled between November 2011 and January 2013. Dogs were diagnosed with PDH or AHAC based on clinical signs and positive screening test results (PDH) or abnormal extended adrenal hormone panel results (AHAC). Transverse adrenal gland measurements were obtained by abdominal ultrasound. Hourly mean cortisol …