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Medicine and Health Sciences Commons

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Veterinary Medicine

Selected Works

SelectedWorks

Infectious disease/modeling

Publication Year

Articles 1 - 3 of 3

Full-Text Articles in Medicine and Health Sciences

Introduction Infectious Disease Modeling, Cristina Lanzas Jul 2013

Introduction Infectious Disease Modeling, Cristina Lanzas

Cristina Lanzas

No abstract provided.


Investigating Effects Of Between- And Within- Host Variability On Escherichia Coli O157 Shedding Pattern And Transmission, Shi Chen, Mike Sanderson, Cristina Lanzas Jan 2013

Investigating Effects Of Between- And Within- Host Variability On Escherichia Coli O157 Shedding Pattern And Transmission, Shi Chen, Mike Sanderson, Cristina Lanzas

Cristina Lanzas

Healthy cattle and their environment are the reservoir for the human pathogen Escherichia coli O157. In E. coli O157 epidemiology, supershedders have been loosely defined as cattle that shed high concentrations of E. coli O157 (≥104 colony-forming cells (CFU)/g of feces) at a single (or multiple) cross-section in time. Due to the variability in the pathogen shedding level among animals (between-host variability), as well as fluctuations in the level shed by a single animal (within-host variability), it is difficult to interpret fecal bacteria distributions, as well as to parse the relative contribution of between- and within-host variability to the observed …


Model Or Meal? Farm Animal Populations As Models For Infectious Diseases Of Humans, Cristina Lanzas, P Ayscue, R Ivanek, Y T. Grohn Feb 2010

Model Or Meal? Farm Animal Populations As Models For Infectious Diseases Of Humans, Cristina Lanzas, P Ayscue, R Ivanek, Y T. Grohn

Cristina Lanzas

In recent decades, theory addressing the processes that underlie the dynamics of infectious diseases has progressed considerably. Unfortunately, the availability of empirical data to evaluate these theories has not grown at the same pace. Although laboratory animals have been widely used as models at the organism level, they have been less appropriate for addressing issues at the population level. However, farm animal populations can provide empirical models to study infectious diseases at the population level.