Medicine and Health Sciences Commons^™

Evaluation Of The Cervidtb Stat-Pak For The Detection Of Mycobacterium Bovis Infection In Wild Deer In Great Britain, S. Gowtage-Sequeira, A. Paterson, K. P. Lyashchenko, S. Lesellier, M. A. Chambers

Michigan Bovine Tuberculosis Bibliography and Database

Deer are acknowledged as hosts of Mycobacterium bovis, the causative agent of bovine tuberculosis (bTB), and determining the prevalence of infection in deer species is one of the key steps in understanding the epidemiological role played by cervids in the transmission and maintenance of bTB in the United Kingdom. This study evaluated a rapid lateral-flow test for the detection of bTB in samples from wild deer species in the United Kingdom. Fallow deer (Dama dama), roe deer (Capreolus capreolus), and red deer (Cervus elaphus) from areas in Wales, the Cotswolds, and southwestern England …

A New Approach For Managing Bovine Tuberculosis: Veterinary Services’ Proposed Action Plan

Michigan Bovine Tuberculosis Bibliography and Database

Bovine tuberculosis (TB) is a serious disease with animal health, public health, and international trade consequences. The cooperative Federal-State-industry effort to eradicate bovine TB from cattle in the United States has made significant progress since the program’s inception in 1917. However, the goal of eradication remains elusive.

This proposed action plan presents Veterinary Services’ (VS’) current thinking about changes we are considering for the TB program to address our current challenges.

This action plan will:
1. Reduce the introduction of TB into the U.S. national herd from imported animals and wildlife by:
o Applying additional requirements to cattle imports from …

Contact Networks In A Wildlife-Livestock Host Community: Identifying High-Risk Individuals In The Transmission Of Bovine Tb Among Badgers And Cattle, Monika Böhm, Michael R. Hutchings, Piran C. L. White

Michigan Bovine Tuberculosis Bibliography and Database

Background: The management of many pathogens, which are of concern to humans and their livestock, is complicated by the pathogens’ ability to cross-infect multiple host species, including wildlife. This has major implications for the management of such diseases, since the dynamics of infection are dependent on the rates of both intra- and inter-specific transmission. However, the difficulty of studying transmission networks in free-living populations means that the relative opportunities for intra- versus inter-specific disease transmission have not previously been demonstrated empirically within any wildlife-livestock disease system.

Methodology/Principal Findings: Using recently-developed proximity data loggers, we quantify both intra-and interspecific contacts in …

Spatial Ecology Of Raccoons Related To Cattle And Bovine Tuberculosis In Northeastern Michigan, Todd Atwood, Thomas Deliberto, Holly Smith, Justin Stevenson, Kurt C. Vercauteren

Michigan Bovine Tuberculosis Bibliography and Database

In 1995, Mycobacterium bovis, the causative bacterium of bovine tuberculosis (bTB), was detected in 5 beef cattle operations in Alcona County, Michigan, USA. In accordance with Federal law, the operations were depopulated to prevent the spread of bTB. Subsequent wildlife surveillance programs identified high prevalence of M. bovis in mesocarnivores, including raccoons ( Procyon lotor), which suggested that raccoons may be complicit in vectoring the pathogen among livestock operations. Our goal was to develop an empirical basis for generating hypotheses about the likelihood for raccoons to mediate the transmission of bTB to livestock. We found intersexual differences in …

Economic Impact Of Bovine Tuberculosis On Minnesota’S Cattle And Beef Sector, Brian Buhr, Kyle Mckeever, Kenji Adachi

Michigan Bovine Tuberculosis Bibliography and Database

In September 2005, the first case of bovine tuberculosis (BTB) in 34 years was discovered in Minnesota and led to a loss of Minnesota’s bovine TB free status. In October 2007 and January and February 2008, four additional cattle herds and deer infected with BTB were discovered in Roseau and Beltrami counties and Minnesota’s BTB status was changed from “modified accredited advanced” to “modified accredited” in April 2008. Each of these designations has increased regulatory requirements (and costs) for animal testing, record keeping, eradication practices, slaughtering and shipments of cattle within state and across state lines.

Humoral Immune Responses Of White-Tailed Deer (Odocoileus Virginianus) To Mycobacterium Bovis Bcg Vaccination And Experimental Challenge With M. Bovis, P. Nol, K. P. Lyashchenko, R. Greenwald, J. Esfandiari, W. R. Waters, M. V. Palmer, B. J. Nonnecke, T. J. Keefe, T. C. Thacker, J. C. Rhyan, F. E. Aldwell, M. D. Salman

Michigan Bovine Tuberculosis Bibliography and Database

Monitoring of the kinetics of production of serum antibodies to multiple mycobacterial antigens can be useful as a diagnostic tool for the detection of Mycobacterium bovis infection as well as for the characterization of disease progression and the efficacy of intervention strategies in several species. The humoral immune responses to multiple M. bovis antigens by white-tailed deer vaccinated with BCG orally via a lipid-formulated bait (n = 5), orally in liquid form (n = 5), and subcutaneously (n = 6) were evaluated over time after vaccination and after experimental challenge with virulent M. bovis and were compared to the responses …

Tuberculosis: A Re-Emerging Disease In Animals And Humans, Charles O. Thoen, Philip A. Lobue, Donald A. Enarson, John B. Kaneene, Isabel N. De Kantor

Michigan Bovine Tuberculosis Bibliography and Database

Tuberculosis continues to be an important disease both in humans and animals. It causes morbidity, mortality, and economic loss worldwide. The occurrence of Mycobacterium bovis disease in humans, domesticated and wild animals confirms the relevance of this zoonosis. M. bovis in humans continues to be reported in industrialized countries and in immigrants from regions of the world where tuberculosis in cattle is endemic. The real incidence of M. bovis in humans in developing countries continues to be roughly underestimated due to the scarcity of appropriate laboratory facilities to isolate and to differentiate M. bovis strains. In Latin America, less than …

Disease, Predation And Demography: Assessing The Impacts Of Bovine Tuberculosis On African Buffalo By Monitoring At Individual And Population Levels, P. C. Cross, D. M. Heisey, J. A. Bowers, C. T. Hay, J. Wolhuter, P. Buss, M. Hofmey, A. L. Michel, R. G. Bengis, T. L. F. Bird, J. T. Du Toit, W. M. Getz

Michigan Bovine Tuberculosis Bibliography and Database

1. Understanding the effects of disease is critical to determining appropriate management responses, but estimating those effects in wildlife species is challenging. We used bovine tuberculosis (BTB) in the African buffalo Syncerus caffer population of Kruger National Park, South Africa, as a case study to highlight the issues associated with estimating chronic disease effects in a long-lived host.

2. We used known and radio-collared buffalo, aerial census data, and a natural gradient in pathogen prevalence to investigate if: (i) at the individual level, BTB infection reduces reproduction; (ii) BTB infection increases vulnerability to predation; and (iii) at the population level, …

Evaluation Of Blood Assays For Detection Of Mycobacterium Bovis In White-Tailed Deer (Odocoileus Virginianus) In Michigan, Daniel J. O’Brien, Stephen M. Schmitt, Konstantin P. Lyashchenko, W. Ray Waters, Dale E. Berry, Mitchell V. Palmer, Jim Mcnair, Rena Greenwald, Javan Esfandiari, Melinda K. Cosgrove

Michigan Bovine Tuberculosis Bibliography and Database

Surveillance and control activities related to bovine tuberculosis (TB) in free-ranging, Michigan white-tailed deer (Odocoileus virginianus) have been underway for over a decade, with significant progress. However, foci of higher TB prevalence on private lands and limited agency ability to eliminate them using broad control strategies have led to development and trial of new control strategies, such as live trapping, testing, and culling or release. Such strategies require a prompt, accurate live animal test, which has thus far been lacking. We report here the ability of seven candidate blood assays to determine the TB infection status of Michigan …

Vaccination With Mycobacterium Bovis Bcg Strains Danish And Pasteur In White-Tailed Deer (Odocoileus Virginianus) Experimentally Challenged With Mycobacterium Bovis, M. V. Palmer, T. C. Thacker, W. R. Waters

Michigan Bovine Tuberculosis Bibliography and Database

Wildlife reservoirs of Mycobacterium bovis represent serious obstacles to the eradication of tuberculosis in domestic livestock and the cause for many faltering bovine tuberculosis eradication programs. One approach in dealing with wildlife reservoirs of disease is to interrupt inter-species and intraspecies transmission through vaccination of deer or cattle. To evaluate the efficacy of BCG vaccination in white-tailed deer, 35 deer were assigned to one of three groups; one s.c. dose of 10⁷ CFU of M. bovis BCG Pasteur (n = 12); 1 s.c. dose of 10⁷ CFU of M. bovis BCG Danish (n = 11); or unvaccinated deer …