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Comparison Of Gross Pathology, Histopathology, And Mycobacterial Culture For The Diagnosis Of Tuberculosis In Elk (Cervus Elaphus), Elizabeth B. Rohonczy, Arumuga V. Balachandran, Thomas W. Dukes, Janet B. Payeur, Jack C. Rhyan, Dennis A. Saari, Terry L. Whiting, Susan H. Wilson, Jerald L. Jarnagin

Michigan Bovine Tuberculosis Bibliography and Database

Using the isolation of Mycobacterium bovis as the reference standard, this study evaluated the sensitivity, specificity and kappa statistic of gross pathology (abattoir postmortem inspection), histopathology, and parallel or series combinations of the two for the diagnosis of tuberculosis in 430 elk and red deer. Two histopathology interpretations were evaluated: histopathology I, where the presence of lesions compatible with tuberculosis was considered positive, and histopathology II, where lesions compatible with tuberculosis or a select group of additional possible diagnoses were considered positive. In the 73 animals from which M. bovis was isolated, gross lesions of tuberculosis were most often in …