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Articles 1 - 5 of 5
Full-Text Articles in Medicine and Health Sciences
Blood Chimerism Confounds Genetic Relative Susceptibility Testing For Classical Scrapie In Sheep, David A. Schneider, Ahmed Tibary, Terje Taudsepp, Pranab J. Das, Katherine I. O'Rourke
Blood Chimerism Confounds Genetic Relative Susceptibility Testing For Classical Scrapie In Sheep, David A. Schneider, Ahmed Tibary, Terje Taudsepp, Pranab J. Das, Katherine I. O'Rourke
Other Publications in Zoonotics and Wildlife Disease
Classical scrapie disease is a transmissible spongiform encephalopathy of sheep that is enzootic in the United States. Susceptibility of sheep to classical scrapie is linked to single nucleotide polymorphisms in the prion protein gene (PRNP), forming the basis for genetic testing strategies used by national efforts to eradicate scrapie. Such efforts are occasionally hampered by inconclusive results stemming from the detection of ‘‘complex’’ genotypes. Naturally occurring cases of ovine chimerism are thought to account for some of these instances. In the current report, 4 naturally occurring ovine chimeras are documented through cytogenetic and molecular analyses. All 4 of these sheep …
Nor98 Scrapie Identified In The United States, Christie M. Loiacono, Bruce V. Thomsen, S. Mark Hall, Matti Kiupel, Diane Sutton, Katherine I. O'Rourke, Bradd Barr, Lucy Anthenill, Delwyn Keane
Nor98 Scrapie Identified In The United States, Christie M. Loiacono, Bruce V. Thomsen, S. Mark Hall, Matti Kiupel, Diane Sutton, Katherine I. O'Rourke, Bradd Barr, Lucy Anthenill, Delwyn Keane
Other Publications in Zoonotics and Wildlife Disease
A distinct strain of scrapie identified in sheep of Norway in 1998 has since been identified in numerous countries throughout Europe. The disease is known as Nor98 or Nor98-like scrapie, among other names. Distinctions between classic scrapie and Nor98 scrapie are made based on histopathology and immunodiagnostic results. There are also differences in the epidemiology, typical signalment, and likelihood of clinical signs being observed. In addition, sheep that have genotypes associated with resistance to classic scrapie are not spared from Nor98 disease. The various differences between classic and Nor98 scrapie have been consistently reported in the vast majority of cases …
Concentration Of Products Of Nitric Oxide Oxidation And Some Vitamins In Sheep With Naturally Acquired Babesiosis, Handan Mert, İbrahi̇m Yörük, Yeter Değer, Ni̇hat Mert, Semi̇ha Dede, Fatmagül Yur
Concentration Of Products Of Nitric Oxide Oxidation And Some Vitamins In Sheep With Naturally Acquired Babesiosis, Handan Mert, İbrahi̇m Yörük, Yeter Değer, Ni̇hat Mert, Semi̇ha Dede, Fatmagül Yur
Turkish Journal of Veterinary & Animal Sciences
The aim of the present study was to determine serum concentrations of the products of nitric oxide oxidation (nitrate and nitrite) and some vitamins (retinol acetate, \alpha- and \delta-tocopherol, and vitamin D_3) in sheep naturally infected with Babesia ovis. The investigation included 30 infected and 10 control sheep. Serum \alpha -tocopherol levels were significantly lower (P < 0.05), and nitrate and nitrite concentrations were significantly higher (P < 0.05) in infected animals than in controls. It is thought that the elevated nitrate and nitrite levels of the sheep infected with babesiosis were due to the result of damage caused by Babesia. On the other hand, a significant decrease was observed in \alpha -tocopherol levels in sheep with babesiosis because of damage and pathophysiological changes to erythrocytes.
Isolation And Biotyping Of Brucella Melitensis From Aborted Sheep And Goat Fetuses, Esra Büyükcangaz, Ayşi̇n Şen, Serpi̇l Kahya
Isolation And Biotyping Of Brucella Melitensis From Aborted Sheep And Goat Fetuses, Esra Büyükcangaz, Ayşi̇n Şen, Serpi̇l Kahya
Turkish Journal of Veterinary & Animal Sciences
The possible role of Brucella spp. in 65 abortion cases, 55 from sheep and 10 from goats, occurring in the birth seasons of 2004 and 2005 in northwestern Turkey was investigated. Colony morphology, agglutination by acriflavin, H2S production, CO2 requirement, dye sensitivity in thionin, basic fuchsin, growth characteristics in streptomycin, lysis with Tbilisi phage, and agglutination with monospecific A- and M antisera were examined for identification and biotyping. The isolates from 21 of 55 sheep and 1 of 10 goat abortion cases were identified as Brucella melitensis. Biotyping revealed that 14, 6, and 1 of 22 Brucella spp. were B. …
Acute Encephalopathy And Clinical Pathology Findings In A Sheep With Chronic Copper Poisoning, Nektarios D. Giadinis, Nikolaos Papaioannoy, Maria Kritsepi-Konstantinou, Nikolaos Roubies, Nikolaos Raikos, Harilaos Karatzias
Acute Encephalopathy And Clinical Pathology Findings In A Sheep With Chronic Copper Poisoning, Nektarios D. Giadinis, Nikolaos Papaioannoy, Maria Kritsepi-Konstantinou, Nikolaos Roubies, Nikolaos Raikos, Harilaos Karatzias
Turkish Journal of Veterinary & Animal Sciences
A 3-year-old East Friesian sheep from a sheep flock that suffered from chronic copper poisoning was forwarded to the Clinic of Farm Animals in the Aristotle University. The animal had signs of a hemolytic disease indicative of chronic copper poisoning and also nervous signs. Laboratory examinations were consistent with chronic copper poisoning. This was confirmed after necropsy and liver toxicological analysis. By blood smear examination, metarubricytosis, basophilic stippling, anisocytosis, and polychromasia were found. Also, brain histopathological examination revealed focal areas of gliosis in the cerebral cortex and white matter areas. Satellitosis, neuronal degeneration (chromatolysis) and neuronophagia were also observed. These …