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Description And Practical Application Of The Physiologic Distribution Of 3’-Deoxy-3’-[18f]Fluorothymidine In Companion Animals, Joshua Alan Rowe

Doctoral Dissertations

Access to positron emission tomography (PET), and more recently PET combined with computed tomography (PET/CT), is increasing in veterinary medicine. This molecular imaging technology allows clinicians to map biological functions within patients based on the distribution and selective uptake of specialized positron-emitting radiopharmaceuticals. Although most clinical studies utilize 2-deoxy-2-[¹⁸F]fluoro-Dglucose (¹⁸FDG), a versatile but relatively nonspecific tracer that interrogates the energy metabolism of tissues, there is a growing need to establish reference values for alternative or adjunct tracers in veterinary species. Among these is 3’-deoxy-3’- [¹⁸F]fluorothymidine (¹⁸FLT), a thymidine analog that selectively accumulates …