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Full-Text Articles in Medicine and Health Sciences

Myofascial Release, Colin S. Hetherington Oct 2019

Myofascial Release, Colin S. Hetherington

Student Publications

Fascia represents an intricate system of connective tissue that permeates throughout the human body. Its matrix of continuous fibers support, protect, divide and suspend both superficial and deep anatomical structures. While once thought to be a passive mesh network, new evidence suggests fascia is much more complicated. Now recognized as an active physiological component of the human body, myofascial health and function has been given much attention clinically. Of the techniques aimed to treat and restore fascial structure and function, myofascial release has been found to promote stability, increase range of motion and most importantly alleviate musculoskeletal pain. This form …


Regulation Of Peripheral Molecular Clocks In Mammalian Tissues And In Vitro Skeletal Muscle Activation Of Amp-Activated Protein Kinase Via Aicar, Alex C. Lupolt, Daniel P. Moorhead, Josef Brandauer Oct 2014

Regulation Of Peripheral Molecular Clocks In Mammalian Tissues And In Vitro Skeletal Muscle Activation Of Amp-Activated Protein Kinase Via Aicar, Alex C. Lupolt, Daniel P. Moorhead, Josef Brandauer

Student Publications

Most organisms possess a common molecular machinery that governs cellular and tissue circadian rhythmicity through a roughly 24-hour transcription-translation feedback loop. It is estimated that up to 15 percent of human genes are influenced by the core clock machinery. It is likely, however, that the metabolic networks affected by the molecular clock differ according to body tissue.

Recent evidence suggests that peripheral molecular clocks are governed to a greater extent by energy availability than by light and dark cycles. AMP-activated protein kinase (AMPK) acts as a cellular fuel gauge within the cell and is activated in response to exercise and …