Medicine and Health Sciences Commons^™

Is Avotermin Safe And Effective Treatment For Scar Improvement In Healthy Males And Females?, Maria Vera Leon

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not avotermin is a safe and effective treatment for scar improvement in healthy males and females.

STUDY DESIGN: Systemic review of three primary research studies published in the English language, one published in 2010 and the other two in 2011.

DATA SOURCES: Two randomized placebo controlled phase II trials and one double blind within patient placebo controlled phase II clinical trial, analyzed and compared the effectiveness in the administration of avotermin against a placebo in the improvement and diminution of scars. All articles were found using Pubmed …

Is Ablative Fractional Co2 Lasering Effective At Reducing The Appearance Of Moderate To Severe Atrophic Acne Scars As Per Patient Reports?, Katie N. Moses

PCOM Physician Assistant Studies Student Scholarship

Objective: Is ablative fractional CO2 lasering effective at reducing the appearance of moderate to severe atrophic acne scars?

Study Design: Review of published articles including one randomized controlled trial with blinded response evaluation, one randomized split-faced clinical study and one clinical trial were used for this review and were selected based on their relevance to the clinical question.

Data Source: The most recent trials examining ablative fractional CO2 lasering for the treatment of moderate to severe atrophic acne scars were found using PubMed.

Outcome Measured: Patient reported reduction in the appearance of atrophic acne scars was the outcome measured.

Results: …

Is Pulse-Dye Laser Therapy An Effective Treatment For Burn Scars?, Slade G. Rankin

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not pulse-dye laser therapy is an effective treatment for burn scars.

STUDY DESIGN: Systematic review of two randomized controlled trials and one case series study published in 1998, 2003, and 2012.

DATA SOURCES: Two randomized controlled trials and one case series study published after 1997 were obtained using Medline and PubMed

OUTCOMES MEASURED: Symptoms of pruritus, pain, and burning sensation measured for improvement by patient survey of pain scales and parent’s reports of complaints in pediatric patients with symptoms by way of pain scales and medication requests. …