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Implementing Service-Learning Projects For The First Time During The Pandemic: Two Instructors’ Inspiration, Motivation And Goals, Lesley Sylvan, Robyn Becker Jun 2022

Implementing Service-Learning Projects For The First Time During The Pandemic: Two Instructors’ Inspiration, Motivation And Goals, Lesley Sylvan, Robyn Becker

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

While much has been written about student experiences with service-learning and factors that sustain university instructors’ experiences in service-learning over time, less is understood about the contexts that prompt instructors to embark on their first experiences of incorporating service-learning into their teaching. The focus of this article is the experiences of two instructors, one tenure track faculty member and one adjunct faculty member, who incorporated service-learning projects into their classes for the first time during the 2020-2021 academic year. Both professors teach within a speech-language pathology graduate program. The timing and context of their first service-learning experiences are important because …


Coupling Articulatory Placement Strategies With Phonemic Awareness Instruction To Support Emergent Literacy Skills In Preschool Children: A Collaborative Approach, Robyn Becker, Lesley Sylvan Apr 2021

Coupling Articulatory Placement Strategies With Phonemic Awareness Instruction To Support Emergent Literacy Skills In Preschool Children: A Collaborative Approach, Robyn Becker, Lesley Sylvan

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: The merits of collaboration between teachers and speech-language pathologists have been extensively highlighted in literature on multitiered educational frameworks. Studies also illustrate the link between articulation, phonemic awareness, and, ultimately, reading skills. This article describes the impact of an intervention targeting articulation and phonemic awareness provided collaboratively to preschool children to enhance emergent literacy skills with the long-term goal of preventing later reading difficulties.

Method: This pilot study involved a bidirectional collaboration between a speech-language pathologist and a teacher by providing articulatory placement strategies to link accurate speech production with early phonemic awareness activities in the context of a …


Creating A Theoretical Framework To Underpin Discourse Assessment And Intervention In Aphasia, Lucy Dipper, Jane Marshall, Mary Boyle, Deborah Hersh, Nicola Botting, Madeline Cruice Feb 2021

Creating A Theoretical Framework To Underpin Discourse Assessment And Intervention In Aphasia, Lucy Dipper, Jane Marshall, Mary Boyle, Deborah Hersh, Nicola Botting, Madeline Cruice

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Discourse (a unit of language longer than a single sentence) is fundamental to everyday communication. People with aphasia (a language impairment occurring most frequently after stroke, or other brain damage) have communication difficulties which lead to less complete, less coherent, and less complex discourse. Although there are multiple reviews of discourse assessment and an emerging evidence base for discourse intervention, there is no unified theoretical framework to underpin this research. Instead, disparate theories are recruited to explain different aspects of discourse impairment, or symptoms are reported without a hypothesis about the cause. What is needed is a theoretical framework that …


Speech Sound Disorder And Visual Biofeedback Intervention: A Preliminary Investigation Of Treatment Intensity, Elaine Hitchcock, Michelle T. Swartz, Melissa Lopez Jan 2019

Speech Sound Disorder And Visual Biofeedback Intervention: A Preliminary Investigation Of Treatment Intensity, Elaine Hitchcock, Michelle T. Swartz, Melissa Lopez

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

A growing body of research suggests that cases of speech sound errors that have not responded to previous intervention can sometimes be eliminated through speech therapy incorporating visual biofeedback. Aside from considerations related to the specific biofeedback type, acquisition and generalization of a motor plan may be linked to treatment intensity. Several researchers have raised the possibility that inadequate dosage levels may present a significant barrier to success. Thus, the current study aimed to assess the relationship between treatment intensity and treatment outcomes. Twenty-nine articles reporting the use of visual biofeedback intervention for speech sound disorder were identified and coded …


Disclosure Of Stuttering And Quality Of Life In People Who Stutter, Michael Boyle, Kathryn M. Milewski, Carolina Beita-Ell Dec 2018

Disclosure Of Stuttering And Quality Of Life In People Who Stutter, Michael Boyle, Kathryn M. Milewski, Carolina Beita-Ell

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: This study investigated the disclosure practices of people who stutter, and the relationship between disclosure of stuttering and quality of life. Method: Participants were 322 adults who stutter recruited from speech-language pathologists and support group leaders. Participants completed a survey that contained items measuring level of disclosure of stuttering, as well as a global measure of self-rated quality of life. Participants were grouped into low, average, and high quality of life subgroups. Analysis of variance tests compared disclosure levels among these subgroups. Results: The low quality of life subgroup reported significantly lower levels of disclosure compared to both the …


Selecting An Acoustic Correlate For Automated Measurement Of American English Rhotic Production In Children, Heather Campbell, Daphna Harel, Elaine Hitchcock, Tara Mcallister Byun Oct 2018

Selecting An Acoustic Correlate For Automated Measurement Of American English Rhotic Production In Children, Heather Campbell, Daphna Harel, Elaine Hitchcock, Tara Mcallister Byun

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: A current need in the field of speech–language pathology is the development of reliable and efficient techniques to evaluate accuracy of speech targets over the course of treatment. As acoustic measurement techniques improve, it should become possible to use automated scoring in lieu of ratings from a trained clinician in some contexts. This study asks which acoustic measures correspond most closely with expert ratings of children’s productions of American English /ɹ/ in an effort to develop an automated scoring algorithm for use in treatment targeting rhotics. Method: A series of ordinal mixed-effects regression models were fit over a large …


Self-Esteem, Self-Efficacy, And Social Support As Predictors Of Communicative Participation In Adults Who Stutter, Michael Boyle, Carolina Beita-Ell, Kathryn M. Milewski, Alison N. Fearon Aug 2018

Self-Esteem, Self-Efficacy, And Social Support As Predictors Of Communicative Participation In Adults Who Stutter, Michael Boyle, Carolina Beita-Ell, Kathryn M. Milewski, Alison N. Fearon

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: This study aimed to identify contributors to communicative participation in adults who stutter. Specifically, it was of interest to determine whether psychosocial variables of self-esteem, self-efficacy, and social support were predictive of communicative participation beyond contributions of demographic and speech-related variables. Method: Adults who stutter (N = 339) completed an online survey that included measures of communicative participation, self-esteem, self-efficacy, social support, self-reported speech-related variables (speech usage, number of years stuttering, history of treatment and self-help support group participation for stuttering, and physical speech disruption severity), and demographics (age, sex, living situation, education, and employment status). Hierarchical regression was …


Self-Stigma And Its Associations With Stress, Physical Health, And Health Care Satisfaction In Adults Who Stutter, Michael Boyle, Alison N. Fearon Jun 2018

Self-Stigma And Its Associations With Stress, Physical Health, And Health Care Satisfaction In Adults Who Stutter, Michael Boyle, Alison N. Fearon

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: The aim of this study was to identify potential relationships between self-stigma (stigma awareness and stigma application) and stress, physical health, and health care satisfaction among a large sample of adults who stutter. It was hypothesized that both stigma awareness and stigma application would be inversely related to measures of physical health and health care satisfaction, and positively related to stress. Furthermore, it was anticipated that stress mediated the relationship between self-stigma and physical health. Method: A sample of adults who stutter in the United States (n = 397) completed a web survey that assessed levels of stigma awareness …


Enacted Stigma And Felt Stigma Experienced By Adults Who Stutter, Michael Boyle May 2018

Enacted Stigma And Felt Stigma Experienced By Adults Who Stutter, Michael Boyle

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: The aim of this study was to (1) document the experiences of enacted stigma (external stigma, experienced discrimination) and felt stigma (anticipation and expectation of discrimination or negative treatment by others) in adults who stutter, (2) investigate their relationships to each other, and (3) investigate their relationships to global mental health. Method: Participants were 324 adults who stutter recruited from clinicians and self-help group leaders in the United States. Participants completed an anonymous web survey consisting of measures of enacted stigma, felt stigma, and global mental health. Data analysis focused on obtaining descriptive statistics for enacted stigma and felt …


Eliciting The Language Sample For Developmental Sentence Scoring: A Comparison Of Play With Toys And Elicited Picture Description, Sarita Eisenberg, Ling Yu Guo, Emily Mucchetti May 2018

Eliciting The Language Sample For Developmental Sentence Scoring: A Comparison Of Play With Toys And Elicited Picture Description, Sarita Eisenberg, Ling Yu Guo, Emily Mucchetti

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: This study investigated whether language samples elicited during play and description of pictured events would yield the same results for developmental sentence scoring (DSS). Method: Two language samples were elicited from 58 three-year-olds. One sample was elicited during play with a parent, and the other sample was elicited by an examiner asking children to talk about pictured events in response to elicitation questions. Results: DSS scores were not significantly different between the play and event description samples. However, sentence points were significantly higher for the play sample than for the event description sample. Although there was a correlation between …


Efficacy Of Electropalatography For Treating Misarticulation Of /R, Elaine Hitchcock, Tara Mcallister Byun, Michelle Swartz, Roberta Lazarus Nov 2017

Efficacy Of Electropalatography For Treating Misarticulation Of /R, Elaine Hitchcock, Tara Mcallister Byun, Michelle Swartz, Roberta Lazarus

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: The purpose of the present study was to document the efficacy of electropalatography (EPG) for the treatment of rhotic errors in school-age children. Despite a growing body of literature using EPG for the treatment of speech sound errors, there is little systematic evidence about the relative efficacy of EPG for rhotic errors. Method: Participants were 5 English-speaking children aged 6;10 to 9;10, who produced/r/ at the word level with < 30% accuracy but otherwise showed typical speech, language, and hearing abilities. Therapy was delivered in twice-weekly 30-min sessions for 8 weeks. Results: Four out of 5 participants were successful in achieving perceptually and acoustically accurate/r/ productions during within-treatment trials. Two participants demonstrated generalization of/r/ productions to nontreated targets, per blinded listener ratings. Conclusions: The present findings support the hypothesis that EPG can improve production accuracy in some children with rhotic errors. However, the utility of EPG is likely to remain variable across individuals. For rhotics, EPG training emphasizes one possible tongue configuration consistent with accurate rhotic production (lateral tongue contact). Although some speakers respond well to this cue, the narrow focus may limit lingual exploration of other acceptable tongue shapes known to facilitate rhotic productions.


Semantic Treatments For Word And Sentence Production Deficits In Aphasia., Mary Boyle Feb 2017

Semantic Treatments For Word And Sentence Production Deficits In Aphasia., Mary Boyle

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

The cognitive domains of language and memory are intrinsically connected and work together during language processing. This relationship is especially apparent in the area of semantics. Several disciplines have contributed to a rich store of data about semantic organization and processing, and several semantic treatments for aphasic word and sentence production impairments have been based on these data. This article reviews the relationships between semantics and memory as they relate to word and sentence production, describes the aphasic language impairments that result from deficits in these areas, and summarizes treatment approaches that capitalize on what we have learned about these …


Sample Size For Measuring Grammaticality In Preschool Children From Picture Elicited Language Samples, Sarita Eisenberg, Ling Yu Guo Jan 2015

Sample Size For Measuring Grammaticality In Preschool Children From Picture Elicited Language Samples, Sarita Eisenberg, Ling Yu Guo

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: The purpose of this study was to investigate whether a shorter language sample elicited with fewer pictures (i.e., 7) would yield a percent grammatical utterances (PGU) score similar to that computed from a longer language sample elicited with 15 pictures for 3-year-old children.

Method: Language samples were elicited by asking forty 3-year-old children with varying language skills to talk about pictures in response to prompts. PGU scores were computed for each of two 7-picture sets and for the full set of 15 pictures.

Results: PGU scores for the two 7-picture sets did not differ significantly from, and were highly …


Test-Retest Stability Of Word Retrieval In Aphasic Discourse, Mary Boyle Jan 2014

Test-Retest Stability Of Word Retrieval In Aphasic Discourse, Mary Boyle

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: This study examined the test-retest stability of select word-retrieval measures in the discourses of people with aphasia who completed a 5-stimulus discourse task. Method: Discourse samples across 3 sessions from 12 individuals with aphasia were analyzed for the stability of measures of informativeness, efficiency, main concepts, noun and verb retrieval, word-finding difficulty, and lexical diversity. Values for correlation coefficients and the minimal detectable change score were used to assess stability for research and clinical decision making. Results: Measures stable enough to use in group research studies included the number of words; the number of correct information units (CIUs); the …


What Works In Therapy: Further Thoughts On Improving Clinical Practice For Children With Language Disorders, Sarita Eisenberg Jan 2014

What Works In Therapy: Further Thoughts On Improving Clinical Practice For Children With Language Disorders, Sarita Eisenberg

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: In this response to Kamhi (2014), the author reviewed research about what does and does not help children with language impairment (LI) to learn grammatical features and considered how that research might inform clinical practice. Method: The author reviewed studies about therapy dose (the number of learning episodes per session) and dose frequency (how learning episodes are spaced over time) and also reviewed studies about dose form, including input characteristics and therapy strategies. Conclusion: Although the research is limited, it offers implications for how clinicians do therapy. Children with LI need many learning episodes clustered together within sessions but …


Discourse Treatment For Word Retrieval Impairment In Aphasia: The Story So Far, Mary Boyle Dec 2011

Discourse Treatment For Word Retrieval Impairment In Aphasia: The Story So Far, Mary Boyle

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Background: Impairment-focused aphasia treatment has an ultimate goal of improving language production in connected speech and communication in daily life. Although impairment-based treatment has typically been carried out in words or sentences, investigations have begun to explore the efficacy of treatment during discourse production. Focusing treatment on an impaired linguistic process during discourse production is a complex and challenging endeavour. Aims: This paper aims to review investigations of discourse treatment for word retrieval impairment in aphasia in order to identify and discuss variables that emerge as being important considerations in clinical practice and continued research. Main Contribution: Seven investigations that …


Understanding The Role Of Neuroscience In Brain Based Products: A Guide For Educators And Consumers, Lesley Sylvan, Joanna A. Christodoulou Mar 2010

Understanding The Role Of Neuroscience In Brain Based Products: A Guide For Educators And Consumers, Lesley Sylvan, Joanna A. Christodoulou

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

The term brain based is often used to describe learning theories, principles, and products. Although there have been calls urging educators to be cautious in interpreting and using such material, consumers may find it challenging to understand the role of the brain and to discriminate among brain based products to determine which would be suitable for specific educational goals. We offer a framework for differentiating the multiple meanings of the brain based label and guidelines for educators and consumers to use when evaluating educational products labeled as brain based. The guidelines include: identifying educational goals and target student populations, aligning …


Semantic Feature Analysis Treatment For Aphasic Word Retrieval Impairments: What's In A Name?, Mary Boyle Jan 2010

Semantic Feature Analysis Treatment For Aphasic Word Retrieval Impairments: What's In A Name?, Mary Boyle

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

This article delineates differences among treatment paradigms that have been called semantic feature analysis treatment and reviews the outcomes of these treatment studies regarding improved naming of treated items, maintenance of treatment effects over time, and generalized improvement to untreated items. Differences in outcomes among the treatment paradigms highlight the importance of using different names for different treatment paradigms.


Nonlinear Source-Filter Coupling In Phonation: Vocal Exercises, Ingo Titze, Tobias Riede, Peter Popolo Apr 2008

Nonlinear Source-Filter Coupling In Phonation: Vocal Exercises, Ingo Titze, Tobias Riede, Peter Popolo

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Nonlinear source-filter coupling has been demonstrated in computer simulations, in excised larynx experiments, and in physical models, but not in a consistent and unequivocal way in natural human phonations. Eighteen subjects (nine adult males and nine adult females) performed three vocal exercises that represented a combination of various fundamental frequency and formant glides. The goal of this study was to pinpoint the proportion of source instabilities that are due to nonlinear source-tract coupling. It was hypothesized that vocal fold vibration is maximally destabilized when F0 crosses F1, where the acoustic load changes dramatically. A companion paper provides the theoretical underpinnings. …


Cross-Modal Interaction Between Vision And Hearing: A Speed—Accuracy Analysis, Yoav Arieh, Lawrence E. Marks Apr 2008

Cross-Modal Interaction Between Vision And Hearing: A Speed—Accuracy Analysis, Yoav Arieh, Lawrence E. Marks

Department of Psychology Faculty Scholarship and Creative Works

Cross-modal facilitation of response time (RT) is said to occur in a selective attention task when the introduction of an irrelevant sound increases the speed at which visual stimuli are detected and identified. To investigate the source of the facilitation in RT, we asked participants to rapidly identify the color of lights in the quiet and when accompanied by a pulse of noise. The resulting measures of accuracy and RT were used to derive speed-accuracy trade-off functions (SATFs) separately for the noise and the no-noise conditions. The two resulting SATFs have similar slopes and intercepts and, thus, can be treated …


Cross-Modal Interaction Between Vision And Hearing: A Speed—Accuracy Analysis, Yoav Arieh, Lawrence E. Marks Apr 2008

Cross-Modal Interaction Between Vision And Hearing: A Speed—Accuracy Analysis, Yoav Arieh, Lawrence E. Marks

Department of Psychology Faculty Scholarship and Creative Works

Cross-modal facilitation of response time (RT) is said to occur in a selective attention task when the introduction of an irrelevant sound increases the speed at which visual stimuli are detected and identified. To investigate the source of the facilitation in RT, we asked participants to rapidly identify the color of lights in the quiet and when accompanied by a pulse of noise. The resulting measures of accuracy and RT were used to derive speed-accuracy trade-off functions (SATFs) separately for the noise and the no-noise conditions. The two resulting SATFs have similar slopes and intercepts and, thus, can be treated …


Translational Research In Aphasia: From Neuroscience To Neurorehabilitation, Anastasia M. Raymer, Pelagie Beeson, Audrey Holland, Diane Kendall, Lynn M. Maher, Nadine Martin, Laura Murray, Miranda Rose, Cynthia K. Thompson, Lyn Turkstra, Lori Altmann, Mary Boyle, Tim Conway, William Hula, Kevin Kearns, Brenda Rapp, Nina Simmons-Mackie, Leslie J. Gonzalez Rothi Feb 2008

Translational Research In Aphasia: From Neuroscience To Neurorehabilitation, Anastasia M. Raymer, Pelagie Beeson, Audrey Holland, Diane Kendall, Lynn M. Maher, Nadine Martin, Laura Murray, Miranda Rose, Cynthia K. Thompson, Lyn Turkstra, Lori Altmann, Mary Boyle, Tim Conway, William Hula, Kevin Kearns, Brenda Rapp, Nina Simmons-Mackie, Leslie J. Gonzalez Rothi

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

Purpose: In this article, the authors encapsulate discussions of the Language Work Group that took place as part of the Workshop in Plasticity/NeuroRehabilitation Research at the University of Florida in April 2005. Method: In this narrative review, they define neuroplasticity and review studies that demonstrate neural changes associated with aphasia recovery and treatment. The authors then summarize basic science evidence from animals, human cognition, and computational neuroscience that is relevant to aphasia treatment research. They then turn to the aphasia treatment literature in which evidence exists to support several of the neuroscience principles. Conclusion: Despite the extant aphasia treatment literature, …


Ethical And Methodological Considerations In Clinical Communication Research With Hispanic Populations, José G. Centeno, Willard Gingerich Jan 2007

Ethical And Methodological Considerations In Clinical Communication Research With Hispanic Populations, José G. Centeno, Willard Gingerich

Department of English Faculty Scholarship and Creative Works

Spanish speakers, whether in monolingual or bilingual situations, or in majority or minority contexts, represent a considerable population worldwide. Spanish speakers in the U.S. constitute an illustrative context of the challenges faced by speech-language practitioners to provide realistic services to an increasing and diverse Spanish-speaking caseload. There is still considerable paucity in the amount of literature on Hispanic individuals with clinical relevance in speech-language pathology. Particularly lacking are works that link both empirical and theoretical bases to evidence-based procedures for child and adult Spanish users with communication disorders. Further, because communication skills depend on multiple phenomena beyond strictly linguistic factors, …


Tracking The Time To Recovery After Induced Loudness Reduction (L), Yoav Arieh, Karen Kelly, Lawrence E. Marks May 2005

Tracking The Time To Recovery After Induced Loudness Reduction (L), Yoav Arieh, Karen Kelly, Lawrence E. Marks

Department of Psychology Faculty Scholarship and Creative Works

In induced loudness reduction (ILR), a strong tone causes the loudness of a subsequently presented weak tone to decrease. The aim of the experiment was to determine the time required for loudness to return to its initial level after ILR. Twenty-four subjects were exposed to 5, 10, 20, or 40 brief bursts of 2500-Hz pure tones at 80-dB SPL (inducers) and then tested in a series of paired comparison trials. Subjects compared the loudness of a weak target (2500 Hz at 60-dB SPL) to the loudness of a comparison tone at 500 Hz previously judged to match the target. The …


Time Course Of Loudness Recalibration: Implications For Loudness Enhancement, Yoav Arieh, Lawrence E. Marks Aug 2003

Time Course Of Loudness Recalibration: Implications For Loudness Enhancement, Yoav Arieh, Lawrence E. Marks

Department of Psychology Faculty Scholarship and Creative Works

Loudness recalibration, the effect of a relatively loud 2500-Hz recalibrating tone on the loudness of a relatively soft 2500-Hz target tone, was measured as a function of the interstimulus interval (ISI) between them. The loudness of the target tone, assessed by a 500-Hz comparison tone, declined when the ISI equaled or exceeded about 200 ms and leveled off at an ISI of about 700 ms. Notably, the target tone’s loudness did not change significantly at very short ISIs (<150 ms). The latter result is incompatible with the literature reporting loudness enhancement in this time window but is compatible with the suggestion made by Scharf, Buus, and Nieder [J. Acoust. Soc. Am. 112, 807–810 (2002)] that early measurements of enhancement were contaminated by the influence of the recalibrating tone on the comparison …


Recalibrating The Auditory System: A Speed–Accuracy Analysis Of Intensity Perception, Yoav Arieh, Lawrence E. Marks Jun 2003

Recalibrating The Auditory System: A Speed–Accuracy Analysis Of Intensity Perception, Yoav Arieh, Lawrence E. Marks

Department of Psychology Faculty Scholarship and Creative Works

Recalibration in loudness perception refers to an adaptation-like change in relative responsiveness to auditory signals of different sound frequencies. Listening to relatively weak tones at one frequency and stronger tones at another make the latter appear softer. The authors showed recalibration not only in magnitude estimates of loudness but also in simple response times (RTs) and choice RTs. RTs depend on the sound intensity and may serve as surrogates for loudness. Most important, the speeded classification paradigm also provided measures of errors. RTs and errors can serve jointly to distinguish changes in sensitivity from changes in response criterion. The changes …


Cerumen Composition By Flash Pyrolysis-Gas Chromatography/Mass Spectrometry, Craig N. Burkhart, Michael A. Kruge, Craig G. Burkhart, Curtis Black Jan 2001

Cerumen Composition By Flash Pyrolysis-Gas Chromatography/Mass Spectrometry, Craig N. Burkhart, Michael A. Kruge, Craig G. Burkhart, Curtis Black

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Objective: To assess the chemical composition of cerumen by flash pyrolysis-gas chromatography/mass spectrometry.

Study Design: Collected earwax specimens were fractionated into residue and supernatant by means of deoxycholate. This natural bile acid produces significantly better disintegration of earwax in vitro than do presently available ceruminolytic preparations, and also has demonstrated excellent clinical results in vivo to date.

Patients: The sample for analysis was obtained from a patient with clinical earwax impaction.

Results: The supernatant is composed of simple aromatic hydrocarbons, C5-Cl 7 straight-chain hydrocarbons, a complex mixture of compounds tentatively identified as diterpenoids, …