Medicine and Health Sciences Commons^™

Socio-Cultural Determinants Of Physical Activity Across The Life Course: A 'Determinants Of Diet And Physical Activity' (Dedipac) Umbrella Systematic Literature Review, Lina Jaeschke, Astrid Steinbrecher, Agnes Luzak, Anna Puggina, Katina Aleksovska, Christoph Buck, Con Burns, Greet Cardon, Angela Carlin, Simon Chantal, Donatella Ciarapica, Giancarlo Condello, Tara Coppinger, Cristina Cortis, Marieke De Craemer, Sara D'Haese, Andrea Di Blasio, Sylvia Hansen, Licia Iacoviello, Johann Issartel, Pascal Izzicupo, Martina Kanning, Aileen Kennedy, Fiona Chun Man Ling, Giorgio Napolitano, Julie Anne Nazare, Camille Perchoux, Angela Polito, Walter Ricciardi, Alessandra Sannella, Wolfgang Schlicht, Rhoda Sohun

Publications

Objective: Regular physical activity (PA) reduces the risk of disease and premature death. Knowing factors associated with PA might help reducing the disease and economic burden caused by low activity. Studies suggest that socio-cultural factors may affect PA, but systematic overviews of findings across the life course are scarce. This umbrella systematic literature review (SLR) summarizes and evaluates available evidence on socio-cultural determinants of PA in children, adolescents, and adults. Methods: This manuscript was drafted following the recommendations of the 'Preferred Reporting Items for Systematic reviews and Meta-Analyses' (PRISMA) checklist. The MEDLINE, Web of Science, Scopus, and SPORTDiscus databases were …

Neighborhood Cohesion, Neighborhood Disorder, And Cardiometabolic Risk, Jennifer N. Robinette, Susan T. Charles, Tara Gruenewald

Psychology Faculty Articles and Research

Perceptions of neighborhood disorder (trash, vandalism) and cohesion (neighbors trust one another) are related to residents’ health. Affective and behavioral factors have been identified, but often in studies using geographically select samples. We use a nationally representative sample (n = 9032) of United States older adults from the Health and Retirement Study to examine cardiometabolic risk in relation to perceptions of neighborhood cohesion and disorder. Lower cohesion is significantly related to greater cardiometabolic risk in 2006/2008 and predicts greater risk four years later (2010/2012). The longitudinal relation is partially accounted for by anxiety and physical activity.

When Your Spouse Is Addicted: How To Avoid Enabling And Get To Reality, Jason B. Whiting

Faculty Publications

Addiction manifests in a variety of ways, from the most severe heroin junkie, to the compulsive spender. It can include drug or alcohol dependence, compulsive pornography use, gambling, obsessive eating, lying, toxic relationships, or even Netflix. When does a habit become an addiction? Any behavior can begin as pleasure or escape, but in the case of addiction, the actions become demands. Addictions are secretive habits the person has unsuccessfully tried to stop, and that have disrupted work and home. An addiction takes an outsized role in the addict’s life and affects those they love.

Hyperhomocysteinemia-Induced Gene Expression Changes In The Cell Types Of The Brain, Erica M. Weekman, Abigail E. Woolums, Tiffany L. Sudduth, Donna M. Wilcock

Sanders-Brown Center on Aging Faculty Publications

High plasma levels of homocysteine, termed hyperhomocysteinemia, are a risk factor for vascular cognitive impairment and dementia, which is the second leading cause of dementia. While hyperhomocysteinemia induces microhemorrhages and cognitive decline in mice, the specific effect of hyperhomocysteinemia on each cell type remains unknown. We took separate cultures of astrocytes, microglia, endothelial cells, and neuronal cells and treated each with moderate levels of homocysteine for 24, 48, 72, and 96 hr. We then determined the gene expression changes for cell-specific markers and neuroinflammatory markers including the matrix metalloproteinase 9 system. Astrocytes had decreased levels of several astrocytic end feet …

Evaluating Spatial Variability In Sediment And Phosphorus Concentration-Discharge Relationships Using Bayesian Inference And Self-Organizing Maps, Kristen L. Underwood, Donna M. Rizzo, Andrew W. Schroth, Mandar M. Dewoolkar

College of Engineering and Mathematical Sciences Faculty Publications

Given the variable biogeochemical, physical, and hydrological processes driving fluvial sediment and nutrient export, the water science and management communities need data-driven methods to identify regions prone to production and transport under variable hydrometeorological conditions. We use Bayesian analysis to segment concentration-discharge linear regression models for total suspended solids (TSS) and particulate and dissolved phosphorus (PP, DP) using 22 years of monitoring data from 18 Lake Champlain watersheds. Bayesian inference was leveraged to estimate segmented regression model parameters and identify threshold position. The identified threshold positions demonstrated a considerable range below and above the median discharge—which has been used previously …

Negative Outcomes Of Teen Sexual Activity: Is There A Regional Effect?, Hannah Latta, Said Shahtahmasebi, Hatim A. Omar

Pediatrics Faculty Publications

A recent victory with respect to teen sexual behavior is the reduction of the national teen birth rate. In 1991, there were 61.8 births per 1000 females aged 15-19. By 2014, this rate plummeted to 24.2 births per 1000 adolescent females. Averages, however, do not reflect state-level variation. For example, in 2014, Kentucky reported 35.3 births per 1000 adolescent females, while New York reported a teen birth rates of 16.1 births per 1000 adolescent females. This report asks: are these discrepancies due to regional factors, and are these differences statistically significant? To examine rural and urban differences in outcomes of …

Simulation As A Multidisciplinary Team Approach In Health Care Programs In An Urban University Setting, Geraldine Fike, Dawn Blue, Guillermo Escalante, Phoebe (Yeon) S. Kim, Jose A. Munoz

Health Science and Human Ecology Faculty Publications

The poster provided here showcases results from a simulation study that began in the Spring Quarter of 2017 at CSU San Bernardino. The results presented here are based on four simulations conducted on campus in our nursing lab space. We incorporated the participation of 44 students in our study.

Patients are cared for by a nurse and multidisciplinary teams which may include physical therapists, social workers, and public health workers; however, students in health care programs usually will not experience necessary scenarios developing needed skills. Although needed skills are learned within the walls of the university they remain in a …

Cerebrovascular Pathology In Down Syndrome And Alzheimer Disease, Elizabeth Head, Michael J. Phelan, Eric Doran, Ronald C. Kim, Wayne W. Poon, Frederick A. Schmitt, Ira T. Lott

Sanders-Brown Center on Aging Faculty Publications

People with Down syndrome (DS) are at high risk for developing Alzheimer disease (AD) with age. Typically, by age 40 years, most people with DS have sufficient neuropathology for an AD diagnosis. Interestingly, atherosclerosis and hypertension are atypical in DS with age, suggesting the lack of these vascular risk factors may be associated with reduced cerebrovascular pathology. However, because the extra copy of APP leads to increased beta-amyloid peptide (Aβ) accumulation in DS, we hypothesized that there would be more extensive and widespread cerebral amyloid angiopathy (CAA) with age in DS relative to sporadic AD. To test this hypothesis CAA, …

A Multi-Country Assessment Of Factors Related To Smallholder Food Security In Varying Rainfall Conditions, Meredith T. Niles, Molly E. Brown

College of Agriculture and Life Sciences Faculty Publications

Given that smallholder farmers are frequently food insecure and rely significantly on rain-fed agriculture, it is critical to examine climate variability and food insecurity. We utilize data from smallholder farmer surveys from 12 countries with 30 years of rainfall data to examine how rainfall variability and household resources are correlated with food security. We find that on average, households that experienced a drier than average year are 3.81 months food insecure, while households within a normal range of rainfall were 3.67 months food insecure, and wetter than average households were 2.86 months food insecure. Reduced odds of food insecurity is …

Genomic Signature Of Adaptive Divergence Despite Strong Nonadaptive Forces On Edaphic Islands: A Case Study Of Primulina Juliae, Jing Wang, Chao Feng, Tenglong Jiao, Eric Bishop Von Wettberg, Ming Kang

College of Agriculture and Life Sciences Faculty Publications

Both genetic drift and divergent selection are expected to be strong evolutionary forces driving population differentiation on edaphic habitat islands. However, the relative contribution of genetic drift and divergent selection to population divergence has rarely been tested simultaneously. In this study, restriction-site associated DNA-based population genomic analyses were applied to assess the relative importance of drift and divergent selection on population divergence of Primulina juliae, an edaphic specialist fromsouthern China. All populations were found with low standing genetic variation, small effective population size (NE), and signatures of bottlenecks. Populations with the lowest genetic variation were most genetically differentiated from other …

In Place: November 27, 2017, Place

PLACE Historical Documents

In PLACE is a newsletter designed to keep the Linfield College community apprised of information related to PLACE activities, as well as ways to bring the program into classes. Included in this issue:

• Spotlight On: "What's the Big Idea"
• Upcoming Events
• PLACE in the News

Research Brief: "Va Disability Compensation And Money Spent On Substance Use Among Homeless Veterans: A Controversial Association", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This research examines the amount of money homeless veterans spend on alcohol and drugs, as well as the association between public support income, i.e. VA disability compensation, and expenditures on alcohol and drugs. Though no association was found between VA disability compensation and substance use, this study does underscore the importance of policy establishing substance abuse treatment for homeless veterans. Future studies on this topic should include more female veterans.

The Complete Chloroplast Genome Of Primulina And Two Novel Strategies For Development Of High Polymorphic Loci For Population Genetic And Phylogenetic Studies, Chao Feng, Meizhen Xu, Chen Feng, Eric J.B. Von Wettberg, Ming Kang

College of Agriculture and Life Sciences Faculty Publications

Background: Primulina Hance is an emerging model for studying evolutionary divergence, adaptation and speciation of the karst flora. However, phylogenetic relationships within the genus have not been resolved due to low variation detected in the cpDNA regions. Chloroplast genomes can provide important information for phylogenetic and population genetic studies. Recent advances in next-generation sequencing (NGS) techniques greatly facilitate sequencing whole chloroplast genomes for multiple individuals. Consequently, novel strategies for development of highly polymorphic loci for population genetic and phylogenetic studies based on NGS data are needed. Methods: For development of high polymorphic loci for population genetic and phylogenetic studies, two …

Why Women Suffer Domestic Violence In Silence: Web-Based Responses To A Blog, Salima Farooq, Tazeen Saeed Ali, Yasmin Parpio, Nasreen Lalani, Muecke Marjorie

School of Nursing & Midwifery

Background & Aim: Domestic violence (DV) is a global socio-cultural concern faced by a majority of women. DV has a negative impact on women’s social, physical, and psychological wellbeing. Objective was to explore perceptions regarding contributing factors to domestic violence among women.
Methods & Materials: A qualitative descriptive exploratory method was applied for the study. Purposive sampling was used to select participants through emails to respond to the web based blog created for the study. 41 worldwide participants shared their perceptions through the blogs in the study. The data were collected using a web-based discussion forum on the Urban Women …

In Place: November 6, 2017, Place

PLACE Historical Documents

In PLACE is a newsletter designed to keep the Linfield College community apprised of information related to PLACE activities, as well as ways to bring the program into classes. Included in this issue:

• Spotlight On: PLACE Sponsored Events
• Upcoming Events
• PLACE in the News

“Hiv-Related Syndemic Pathways And Risk Subjectivities Among Gay And Bisexual Men: A Qualitative Investigation, Barry D. Adam

Sociology, Anthropology, and Criminology Publications

Life history interviews were conducted with 40 gay and bisexual men to identify modes of syndemic experience and risk practice. Out of the interview narratives emerged one major and two minor modes of developmental pathways whereby syndemic conditions are navigated and expressed: (1) a combination of adverse childhood events with later episodes of depression and/or substantial substance use, (2) personal disruption that led to periods of depression and anxiety associated with the stresses of migration, and (3) a disorientation and an unravelling of life trajectory in the transition from family of origin to college or work. Risk practices fell into …

Evaluating Patient Preferences For Different Incentive Programs To Optimize Pharmacist-Provided Patient Care Program Enrollment, Daniel M. Tomaszewski, Tim Cernohaus, Rajiv Vaidyanathan

Pharmacy Faculty Articles and Research

BACKGROUND: Employers have increased efforts to engage employees in health and wellness programs. Providing employees with incentives to participate in these programs has been shown to improve overall enrollment and engagement. One program that has had challenges with enrollment and engagement is medication therapy management (MTM).

OBJECTIVES: To (a) determine how individuals evaluate different financial incentives to improve participation in an MTM program and (b) measure the effect of participant characteristics on incentive preference.

METHODS: This study was composed of a paper-based survey administered to participants after focus group sessions. Participants included MTMeligible beneficiaries from 2 employer groups and included …

How Useful Is Gsv As An Environmental Observation Tool? An Analysis Of The Evidence So Far., Katherine Nesse, Leah Airt

SPU Works

Researchers in many disciplines have turned to Google Street View to replace pedestrian- or carbased in-person observation of streetscapes. It is most prevalent within the research literature on the relationship between neighborhood environments and public health but has been used as diverse as disaster recovery, ecology and wildlife habitat, and urban design. Evaluations of the tool have found that the results of GSV-based observation are similar to the results from in-person observation although the similarity depends on the type of characteristic being observed. Larger, permanent and discrete features showed more consistency between the two methods and smaller, transient and judgmental …

In Place: October 11, 2017, Place

PLACE Historical Documents

In PLACE is a newsletter designed to keep the Linfield College community apprised of information related to PLACE activities, as well as ways to bring the program into classes. Included in this issue:

• A Message to Faculty
• Spotlight On: Jonathan Rauch & Cheryl Harris
• Upcoming Events
• PLACE in the News
• Last Week in PLACE

A Social Network Study To Improve Collaborative Partnerships Among The Southeastern Health Equity Council (Shec), Candace Forbes Bright, Hannah Scott, Braden Bagley, Jonathan Dennis

Faculty Publications

This report presents research conducted on the relationships among and attributes of members of the Southeastern Health Equity Council (SHEC, herein Council) to provide recommendations for partnerships, collaboration, and the recruitment of new members. The background, methods, results, and recommendations are outlined in detail throughout this report. Social networks are measured and defined as connections among people, organization, and/or other units. SNA is a valuable and innovative tool for recognizing strengths and weaknesses in collaborative partnerships. The evaluative study presented herein can be replicated in other councils within the Regional Health Equity Councils to improve collaborations not only among SHEC …

Gender Differences In Virologic Response After Antiretroviral Therapy In Treatment-Naïve Hiv-Infected Individuals: Results From The 550 Clinic Hiv Cohort Study., Andrea Reyes-Vega, Alejandra Loban, Kavitha Srinivasan, Stephen P. Furmanek, Conner English, Mary Bishop, Cathy Spencer, Daniel Truelove, Julio A. Ramirez, Anupama Raghuram, Paula Peyrani

Faculty Scholarship

Background

Controversy still exists regarding gender differences in virologic response between treatment-na•ve HIV-infected individuals. The objective of this study was to evaluate gender difference in virologic and immunologic response to antiretroviral therapy in treatment-na•ve HIV-infected individuals. Methods

This was a retrospective, observational study of treatment-na•ve HIV-infected individuals managed at the 550 clinic who started antiretroviral therapy (ART) between January 1st, 2010 and December 31, 2015. Patients with available viral load and CD4 counts before and one year after initiating ART were included in this study. Virologic suppression was defined as < 48 HIV-1 RNA copies/mL, and mmunologic recovery was defined as a CD4 count increase of at least 150 cells/mm3. Dichotomous variables were reported in number and percentages and analyzed using Chi-squared tests and Fisher’s exact (whichever was appropriate). Continuous variables were reported as median and interquartile range (IQR) and analyzed using Wilcox rank-sum tests. Multivariate analyses performed were logistic regressions with adjustment for other covariates. P value <0.05 was considered statistically significant. R version 3.3.2 was used for the statistical analysis. Results

A total of 70 women and 90 men were included …

Studying Human Behavior For Species Conservation, Hilary Byerly, Brendan Fisher

Rubenstein School of Environment and Natural Resources Faculty Publications

No abstract provided.

Service Provider Promising Practice - Transcen’S Worklink Program: Helping Individuals Gain Work Skills Through Targeted Volunteering And Other Community Life Engagement Activities, Heike Boeltzig, Thinkwork! At The Institute For Community Inclusion At Umass Boston

ThinkWork! Publications

WorkLink is a program that enables individuals with intellectual and developmental disabilities (IDD) to work while receiving wrap-around day services. Having access to both types of supports -- community employment and Community Life Engagement (CLE) -- is particularly important for individuals with significant IDD, who often work fewer hours and need additional support to lead active and meaningful lives. The program was started in 1996 by TransCen, Inc., and is based in San Francisco, California. Day services not only help individuals establish and maintain meaningful community relationships, but also let them build important skills as they explore vocational goals and …

Service Provider Promising Practice: Flexible Scheduling And Creative Staffing - Kfi’S Support Solutions, Heike Boeltzig, Thinkwork! At The Institute For Community Inclusion At Umass Boston

ThinkWork! Publications

Headquartered in a small rural town in northern Maine, Katahdin Friends, Inc. (KFI) provides community employment and life engagement supports, as well as home supports, to individuals with intellectual and developmental disabilities (IDD). KFI’s services extend throughout northern and southern Maine, including the cities of Portland and Bangor. A flexible approach to staffing and support scheduling helps KFI ensure customized daily support schedules that meet individual goals. This approach also allows individuals to interact with a variety of direct support professionals, which is important for having a more engaged and meaningful life in the community. As of July 2016, KFI …

Service Provider Promising Practice: Braiding Community Employment And Life Engagement Services - Transcen’S Worklink Program, Heike Boeltzig, Thinkwork! At The Institute For Community Inclusion At Umass Boston

ThinkWork! Publications

WorkLink is a program that braids community employment and life engagement services. The goal is to enable individuals with intellectual and developmental disabilities (IDD) to work while receiving wrap-around day supports, as needed. Started in 1996, WorkLink is a program of TransCen, Inc. and is based in San Francisco. WorkLink clients do not have to give up day supports when deciding to pursue work. In addition to helping individuals establish and maintain meaningful community relationships, day supports are used to discover and explore vocational goals and job options. This information then helps guide individuals’ employment planning process. At WorkLink clients …

Service Provider Promising Practice: Avenues Supported Living Services: A Staffing Approach Based On Client Relationships, Heike Boeltzig, Thinkwork! At The Institute For Community Inclusion At Umass Boston

ThinkWork! Publications

Avenues Supported Living Services of Valencia, California was founded in 1997 by a husband- andwife team, Scott and Lori Shepard. The agency provides supported living and community life engagement (CLE) services to individuals with intellectual and developmental disabilities (IDD). Key to Avenues’ success is a staffing approach that is grounded in client relationships. The agency limits staff hours to two shifts per week with the same individual. This is done to facilitate clientstaff matching and relationship building, but also to prevent potential burnout and frustration by ensuring both the clients they support and their staff have variety in their schedules. …

Opportunities And Challenges For Self-Monitoring Technologies For Healthy Aging: An In-Situ Study, Mirana Randriambelonoro, Yu Chen, Onur Yuruten, Pearl Pu

Faculty Publications, Information Systems & Technology

The current need to adopt a healthy lifestyle opens the way for researchers to investigate the efficiency of using technology to motivate a change towards such behavior. Senior people’s technology adoption barriers have been largely investigated in previous research but remain unclear to design efficient solution to promote behavior change in the long term. In this paper, we present the findings of an experiment with 20 older adults using pervasive sensors for 6 weeks at their homes. In particular, we present their attitudes for physical activities and self-monitoring technologies before and after the actual usage. We then discuss the opportunities …

International Black-Market Organ Trade, Marni E. Granzow

Student Publications

The human organ trade is a global epidemic as citizens of developed-countries look to developing-countries to find organ donors, specifically exploiting the poor for their own personal gain. The impoverished organ donors are treated in an inhumane manner, as they are often left with serious medical complications and are not treated equally in the transaction.

Hiv Harm Reduction Methods: A Comparison Between Switzerland And The United States, Erin Major

Independent Study Project (ISP) Collection

This paper explores the connections between harm reduction methods and the prevalence of HIV/AIDS in Switzerland and the United States of America, focusing primarily on the harm reduction methods of needle exchange programs, safe drug consumption spaces, and sex education. While these two countries are largely similar in their culture and geopolitical approaches, there are some key differences in how HIV is approached in each. Switzerland’s somewhat unique approach with relaxed drug policies and more pragmatic, harm reduction based response to the AIDS epidemic sets a model framework for other countries to follow, with comparatively widespread use of needle exchange …

The Opioid Epidemic: A Practice And Policy Perspective, Gail D'Onofrio

Center for Policy Research

I will be talking about the escalating opioid epidemic and some innovative solutions my colleagues and I at Yale University and throughout the state of Connecticut, are working on to mitigate the consequences of this public health crisis.