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Full-Text Articles in Medicine and Health Sciences
Early Surgical Stabilization Of Rib Fractures (Ssrf) Is Better, But Delayed Ssrf Is Not Worse, Stephen J. Bordes, Patrick Greiffenstein
Early Surgical Stabilization Of Rib Fractures (Ssrf) Is Better, But Delayed Ssrf Is Not Worse, Stephen J. Bordes, Patrick Greiffenstein
School of Medicine Faculty Publications
Comment on; Belaroussi Y, Drevet G, Soldea V, et al. When to proceed to surgical rib fixation?-A single-institution clinical experience. J Thorac Dis 2023;15;323-34.
Cocaine Use Disorder Effects On Blood Oxytocin Levels And Oxtr Dna Methylation, Manassés Soares Souza, Breno Sanvicente-Vieira, Aline Zaparte, Talita Baptista, Maria Aparecida Nagai, Flávia Rotea Mangone, Ana Carolina Pavanelli, Thiago Wendt Viola, Rodrigo Grassi-Oliveira
Cocaine Use Disorder Effects On Blood Oxytocin Levels And Oxtr Dna Methylation, Manassés Soares Souza, Breno Sanvicente-Vieira, Aline Zaparte, Talita Baptista, Maria Aparecida Nagai, Flávia Rotea Mangone, Ana Carolina Pavanelli, Thiago Wendt Viola, Rodrigo Grassi-Oliveira
School of Medicine Faculty Publications
Substance use disorders have been associated with alterations in the oxytocinergic system, but few studies have investigated both the peptide and epigenetic mechanisms potentially implicated in the regulation of oxytocin receptor. In this study, we compared plasma oxytocin and blood DNA methylation in the OXTR gene between people with and without cocaine use disorder (CUD). We measured the oxytocin levels of 51 people with CUD during acute abstinence and of 30 healthy controls using an enzyme immunoassay. The levels of DNA methylation in four CpG sites at exon III of the OXTR gene were evaluated in a subsample using pyrosequencing. …