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Full-Text Articles in Medicine and Health Sciences
Pleurodesis Using Hypertonic Glucose Administration To Treat Post-Operative Air Leaks Following Lung Resection Surgery (Plug): Phase I Trial, Mehdi Qiabi
Electronic Thesis and Dissertation Repository
Introduction: Pulmonary air leaks from unhealed lung tissue are one of the most common complications after lung surgery. This adverse event leads to a delay in chest tube removal, prolonged pain, increased infections, prolonged hospital stay, and increased costs to the health care system. Objective: To define the most appropriate safe dose of dextrose 50% (D50) to seal air leaks in patients that have undergone lung resection surgery. Primary outcome was the occurrence of any adverse event. Methods: Prospective, single-arm, single-center, rule-based escalation traditional 3+3 design phase I trial where patients with an active air leak on …
Validation Of An Algorithm Allowing Identification Of Primary Spontaneous Pneumothorax Cases From Administrative Databases, Eric Frechette
Validation Of An Algorithm Allowing Identification Of Primary Spontaneous Pneumothorax Cases From Administrative Databases, Eric Frechette
Electronic Thesis and Dissertation Repository
Introduction: There is no differentiation between primary spontaneous pneumothorax (PSP) and secondary pneumothorax (SP) in the current version of the International Classification of Diseases (ICD-10). Objective: To validate the accuracy of an algorithm that identifies cases of PSP from administrative databases. Methods: The charts of 150 patients who attended the emergency room (ER) with a recorded main diagnosis of pneumothorax were reviewed. The corresponding hospital administrative data collected during previous hospitalizations and ER visits were processed through the proposed algorithm. The results were compared over two different age groups. Results: The results obtained from the PSP algorithm demonstrated a significantly …