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Full-Text Articles in Medicine and Health Sciences

Genome-Wide Association Analysis Of Major Depressive Disorder And Its Related Phenotypes., Nagesh Ramarao Aragam Dec 2011

Genome-Wide Association Analysis Of Major Depressive Disorder And Its Related Phenotypes., Nagesh Ramarao Aragam

Electronic Theses and Dissertations

Major Depressive Disorder (MDD) is a complex and chronic disease that ranks fourth as cause of disability worldwide. Thirteen to 14 million adults in the U.S. are believed to have MDD and an estimated 75% attempt suicide making MDD a major public health problem. Recently several genome-wide association (GWA) studies of MDD have been reported; however, few GWA studies focus on the analysis for MDD related phenotypes such as neuroticism and age at onset of MDD. The purpose of this study is to determine risk factors for MDD, identify genome-wide genetic variants affecting neuroticism and age at onset as quantitative …


Effect Of Gender On The Association Of Single-Nucleotide Polymorphisms With Bipolar Disorder, Jerald Eric Mullersman Dec 2011

Effect Of Gender On The Association Of Single-Nucleotide Polymorphisms With Bipolar Disorder, Jerald Eric Mullersman

Electronic Theses and Dissertations

Bipolar disorder is a relatively common form of mental illness that depends strongly on genetic inheritance for expression. The author of this study has sought to evaluate whether the gender of subjects influences which genetic variants are associated with the disease. A portion of the cases from a previously published study were analyzed using PLINK software and the association of single-nucleotide polymorphisms was evaluated separately for all cases, for female subjects alone, and for male subjects alone. The results obtained for male subjects alone reached higher levels of statistical significance than when both genders were evaluated together or when female …


Evaluation Of A Quality Management Initiative And Hiv Ambulatory Services Performance In Thailand, Meemon Natthani Jan 2011

Evaluation Of A Quality Management Initiative And Hiv Ambulatory Services Performance In Thailand, Meemon Natthani

Electronic Theses and Dissertations

The accomplishment of pilot implementation of the HIVQUAL-T model, an innovative HIV care quality management tool, has led to an authoritative decision to scale up the use of the model nationwide in Thailand. However, the level of implementing this model varies across target hospitals. Some hospitals have fully adopted the model by conducting quality improvement (QI) activities following performance measurement (PM) results while others have partially adopted only PM or have not used this model at all. The differential level of implementation could be a contributing factor accounting for discrepancies in the quality of care across different HIV ambulatory care …


The Role Of Policy And The Built Environment On Children's In-School Physical Activity In The Mississippi Delta, Abigail Gamble Jan 2011

The Role Of Policy And The Built Environment On Children's In-School Physical Activity In The Mississippi Delta, Abigail Gamble

Electronic Theses and Dissertations

School environments provide an ideal setting for children to develop and adopt active living behaviors as a way of life. The primary purpose of this investigation was to describe state, district and school level policy regarding in-school physical activity, the school built environment and in-school physical activity of children ages 6 through 11 years in the Mississippi delta. A mixed-methods approach was used to garner a rich understanding of how current policy and the built environment influence in-school physical activity and weight status. Eleven public schools in three districts representing two counties in the Mississippi delta participated in this investigation. …


Professional Preparation Of Secondary Health Education Teachers In Mississippi, Ensley Howell Jan 2011

Professional Preparation Of Secondary Health Education Teachers In Mississippi, Ensley Howell

Electronic Theses and Dissertations

The purpose of this study was to examine the professional preparation of secondary health education teachers in Mississippi. All four-year institutions of higher learning were contacted to determine the requirements for an approved program in order to obtain a supplemental endorsement in health, to compare the similarities and differences, and to determine the extent to which the approved programs reflect the ten content areas of the Mississippi Comprehensive Health Framework. This study also examined the status of secondary school health education programs in Mississippi by utilizing selected data from the U.S. Department of Health and Human Services Centers for Disease …