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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Public Health

University of Wisconsin Milwaukee

Theses/Dissertations

2020

DNA methylation

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Life Course Health Effects Of Early Life Trauma, Jennifer Mei Ping Woo May 2020

Life Course Health Effects Of Early Life Trauma, Jennifer Mei Ping Woo

Theses and Dissertations

The experience of trauma and psychosocial stress over the life course can have lasting impacts on health. Childhood and adolescence may serve as a particularly sensitive period during which trauma may become biologically embedded and affect adult health. Evaluating the pathways through which early life trauma can affect biological mechanisms of disease development provides insight into the early origins and etiology of adverse health outcomes in adulthood and provides potential targets to help mitigate their effects.

Using data from the Sister Study, a large prospective cohort study of women residing in the U.S. or Puerto Rico aged 35 to 74 …