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Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Public Health

University of Texas Rio Grande Valley

2014

Schizophrenia

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Full-Text Articles in Medicine and Health Sciences

Pd_Ngsatlas: A Reference Database Combining Next-Generation Sequencing Epigenomic And Transcriptomic Data For Psychiatric Disorders, Zheng Zhao, Yongsheng Li, Hong Chen, Jianping Lu, Peter M. Thompson, Juan Cheng, Zishan Wang, Juan Xu, Chun Xu, Xia Li Jan 2014

Pd_Ngsatlas: A Reference Database Combining Next-Generation Sequencing Epigenomic And Transcriptomic Data For Psychiatric Disorders, Zheng Zhao, Yongsheng Li, Hong Chen, Jianping Lu, Peter M. Thompson, Juan Cheng, Zishan Wang, Juan Xu, Chun Xu, Xia Li

Health & Biomedical Sciences Faculty Publications and Presentations

Background: Psychiatric disorders such as schizophrenia (SZ) and bipolar disorder (BP) are projected to lead the global disease burden within the next decade. Several lines of evidence suggest that epigenetic- or genetic-mediated dysfunction is frequently present in these disorders. To date, the inheritance patterns have been complicated by the problem of integrating epigenomic and transcriptomic factors that have yet to be elucidated. Therefore, there is a need to build a comprehensive database for storing epigenomic and transcriptomic data relating to psychiatric disorders.

Description: We have developed the PD_NGSAtlas, which focuses on the efficient storage of epigenomic and transcriptomic data based …