Medicine and Health Sciences Commons^™

Ambient Ozone And Cadmium As Risk Factors For Congenital Diaphragmatic Hernia, Rema Ramakrishnan

USF Tampa Graduate Theses and Dissertations

Congenital diaphragmatic hernia (CDH) results from a defect in the diaphragm through which abdominal contents enter the thorax displacing the heart and the lungs. This causes lung hypoplasia and varying degrees of pulmonary hypertension resulting in high rates of morbidity and mortality. Though CDH has a prevalence rate of 2.61 per 10,000 live births it is an expensive birth defect with an estimated annual cost of nearly $250 million for all CDH survivors. Maternal exposure to air pollutants have not been studied as risk factors for CDH in humans. Ambient ozone has been found to be risk factors for certain …

Ambient Benzene And Pm2.5 Exposure During Pregnancy: Examining The Impact Of Exposure Assessment Decisions On Associations Between Birth Defects And Air Pollution, Jean Paul Tanner

USF Tampa Graduate Theses and Dissertations

In the United States, approximately 3% of infants are diagnosed with a major birth defect each year. Whereas prevention efforts have led to decreases in some birth defects, the cause of approximately 70% of birth defects remains unknown. More recently, there has been increasing concern regarding exposures to environmental agents, such as air pollution during pregnancy, and the risk of birth defects. Over the past decade, there has been an increase in research studies examining the association between air pollution and birth defects. The results have been inconsistent, with some studies reporting that higher levels of exposure from the same …

Statistical Analysis And Modeling Of Pm2.5 Speciation Metals And Their Mixtures, Boubakari Ibrahimou

USF Tampa Graduate Theses and Dissertations

Exposure to fine particulate matter (PM_2.5) in the ambient air is associated with various health effects. There is increasing evidence which implicates the central role played by specific chemical components such as heavy metals of PM_2.5. Given the fact that humans are exposed to complex mixtures of environmental pollutants such as PM_2.5, research efforts are intensifying to study the mixtures composition and the emission sources of ambient PM, and the exposure-related health effects. Factor analysis as well source apportionment models are statistical tools potentially useful for characterizing mixtures in PM_2.5. However, classic …

A Pilot Study Of Small-Scale Variations In Outdoor Benzene Concentrations, Samantha Catherine Fridh

USF Tampa Graduate Theses and Dissertations

Benzene is an important toxic chemical in urban air and known human carcinogen released substantially by mobile sources. It's important to understand the spatial variation of benzene concentrations in order to understand exposures of susceptible sub-populations such as children and minority groups. Current monitoring networks use large and expensive air samplers that require electricity and restrict the location and number of samplers, not allowing for fine spatial resolution data.

The goals of this study are to develop and evaluate protocols for passive sampling and analysis of ambient benzene concentrations, and conduct a pilot study investigating small-scale variations over an area …