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Troubled By Heterogeneity? Control, Infrastructure & Participation In Social Epidemiology And Life Course Development, Peter J. Taylor

Working Papers on Science in a Changing World

This working paper presents the panels of a poster prepared for a conference, “Complex Systems, Health Disparities, and Population Health: Building Bridges,” held at NIH in Bethesda, MD in February 2014. Just as poster presenters hope viewers stop and talk, my aim in sharing the panels as a working paper is to elicit more conversation about different kinds of heterogeneity and the ways they are addressed or suppressed in social epidemiology and life course development. The thinking behind this concern is as follows. The two foundational developments of modern biology—the theories of evolution by natural selection and the genetic basis …

Heterogeneity, Control, Social Infrastructure, And Possibilities Of Participation: Their Interplay In Modern Understandings Of Heredity And In Interpretation Of Science, Peter J. Taylor

Working Papers on Science in a Changing World

This working paper is a prospectus for research, writing, and engagement. It consists of vignettes, sketches of lines of inquiry, and proposals for engagement, all of which concern modern understandings of heredity and development over the life course as well as the social interpretation of science. The various items address a range of areas of science and of its interpretation: heritability studies, the social uses of genetic information, gene-by-environment interaction, personalized medicine, IQ paradoxes, racial group membership, biobanks, and life events and difficulties research. Fresh perspectives in these areas are opened up by examining the ways that research and application …

Characteristics Of Chronic Pain Associated With Sleep Difficulty In Older Adults: The Maintenance Of Balance, Independent Living, Intellect, And Zest In The Elderly (Mobilize) Boston Study, Suzanne G. Leveille Phd, Qian Chen Bsn, Rn

Suzanne G. Leveille

OBJECTIVES: To evaluate pain severity and distribution

in relation to sleep difficulty in older adults.

DESIGN: Population-based cross-sectional study.

SETTING: Community within a 5-mile radius of the study

center at the Institute for Aging Research, Hebrew Senior-

Life (HSL), Boston.

PARTICIPANTS: Seven hundred sixty-five participants of

the Maintenance of Balance, Independent Living, Intellect,

and Zest in the Elderly (MOBILIZE) Boston Study aged 64

and older.

MEASUREMENTS: Pain severity was measured using the

Brief Pain Inventory (BPI) Pain Severity Subscale. Musculoskeletal pain distribution was grouped according to no pain, single site, two or more sites, and widespread pain

(upper and lower …

Comparing Pain Severity Versus Pain Location In The Mobilize Boston Study: Chronic Pain And Lower Extremity Function, Suzanne G. Leveille, Laura H.P. Eggermont

Suzanne G. Leveille

Background. This study compared measures of chronic pain, for example, number of pain sites and overall pain

severity, in relation to lower extremity function in the older population.

Methods. Six hundred older adults (mean age 77.9 years, 64% female) were queried about presence of chronic pain.

Number of pain sites was categorized as none, single site, multisite, or widespread. Pain severity was measured in

quartiles of the Brief Pain Inventory pain severity subscale. Lower extremity function was assessed by the Short Physical Performance Battery (SPPB), a composite measure of gait speed, balance, and chair stands.

Results. Many older persons reported …

The Acquired Immunodeficiency Syndrome In New England: An Epidemiological Review Of The First Six Years, Laureen M. Kunches, Jeanne M. Day

New England Journal of Public Policy

Between 1981 and 1987 — the six-year period following initial recognition of the acquired immunodeficiency syndrome (AIDS) — 1,475 cases were reported among residents of the six New England states. Of nearly 40,000 cases nationwide, 3.8 percent occurred among New England residents, though the region 's population represents 5.5 percent ofthe total United States population. The groups most affected include homosexual or bisexual men (65 percent) and intravenous drug users (20 percent). However, in the two southernmost states — Rhode Island and Connecticut — 32 to 40 percent of all cases have used intravenous drugs. In these states, the male:female …