Medicine and Health Sciences Commons^™

Profiles And Correlates Of Language And Social Communication Differences Among Young Autistic Children, Rachel Reetzke, Vini Singh, Ji Su Hong, Calliope B. Holingue, Luther G. Kalb, Natasha N. Ludwig, Deepa Menon, Danika L. Pfeiffer, Rebecca J. Landa

Communication Disorders & Special Education Faculty Publications

Delays in early language development are characteristic of young autistic children, and one of the most recognizable first concerns that motivate parents to seek a diagnostic evaluation for their child. Although early language abilities are one of the strongest predictors of long-term outcomes, there is still much to be understood about the role of language impairment in the heterogeneous phenotypic presentation of autism. Using a personcentered, Latent Profile Analysis, we first aimed to identify distinct patterns of language and social communication ability in a clinic-based sample of 498 autistic children, ranging in age from 18 to 60 months (M = …

An Evaluation Of Wayfinding Abilities In Adolescent And Young Adult Males With Autism Spectrum Disorder, Yingying Yang, Weijia Li, Dan Huang, Wei He, Yanxi Zhang, Edward Merrill

Department of Psychology Faculty Scholarship and Creative Works

Background

Wayfinding refers to traveling from place to place in the environment. Despite some research headway, it remains unclear whether individuals with Autism Spectrum Disorder (ASD) show strengths, weaknesses, or similarities in wayfinding compared with ability-matched typically developing (TD) controls.

Method

The current study tested 24 individuals with ASD, 24 mental-ability (MA) matched TD (MA-TD) controls, and 24 chronological-age (CA) matched TD (CA-TD) controls. Participants completed a route learning task and a survey learning task, both programmed in virtual environments, and a perspective taking task. Their parents completed questionnaires assessing their children’s everyday wayfinding activities and competence.

Results

Overall, CA-TD …

Job Seeking And Daily Workforce Experiences Of Autistic Librarians, Amelia Anderson

STEMPS Faculty Publications

Anecdotal accounts suggest that librarianship is a rewarding career for some autistic adults, though no empirical evidence exists to support such claims. Additionally, barriers may exist for autistic librarians, both in job seeking and in on-the-job experiences. As autistic adults are un- and underemployed more than their neurotypical peers, it is important to understand the role that libraries can play in supporting their employment. In this qualitative study, ten librarians with graduate degrees, who self-identify as autistic, describe their experiences in job seeking and daily working experiences in the library field through interviews in multiple formats. Results indicate issues around …

Searching For Neural Mechanisms Of Social Cognition, Chandler Siemonsma, Cristina Uribe, Louanne Boyd, Aaron Schurger, Deanna Hughes, Tian Lan

Student Scholar Symposium Abstracts and Posters

Social cognition involves the integration and pruning of perceptual information which leads to the formation of an abstract representation, which is also known as the perceptual gist. This study examined 87 differences in visual perception of Mooney face stimuli of differing sizes and the relationship to gist formation in ten individuals with autism compared to neurotypical controls. Parents of both groups completed the Social Responsiveness Scale (SRS-2) to assess social functioning in real-world scenarios.

Corrigendum: Saccade Latency Provides Evidence For Reduced Face Inversion Effects With Higher Autism Traits (Frontiers In Human Neuroscience, (2020), 13, 10.3389/Fnhum.2019.00470), Robin Laycock, Kylie Wood, Andrea Wright, Sheila G. Crewther, Melvyn A. Goodale

Brain and Mind Institute Researchers' Publications

Copyright © 2020 Laycock, Wood, Wright, Crewther and Goodale. In the original article, there was a mistake in the published legend for Figure 2. The results for the high and low Autism Trait (AT) groups were mistakenly interchanged. The correct legend appears below. Figure 2. (A) Average saccade onset times (SOTs) to detect the photograph containing a face or a car in the upright and inverted tasks for high and low Autism Trait (AT) Groups. (B) Face and car inversion effects, calculated as the difference in mean SOTs between upright and inverted tasks for high and low AT Groups. Error …

Saccade Latency Provides Evidence For Reduced Face Inversion Effects With Higher Autism Traits, Robin Laycock, Kylie Wood, Andrea Wright, Sheila G. Crewther, Melvyn A. Goodale

Brain and Mind Institute Researchers' Publications

© Copyright © 2020 Laycock, Wood, Wright, Crewther and Goodale. Individuals on the autism spectrum are reported to show impairments in the processing of social information, including aspects of eye-movements towards faces. Abnormalities in basic-level visual processing are also reported. In the current study, we sought to determine if the latency of saccades made towards social targets (faces) in a natural scene as opposed to inanimate targets (cars) would be related to sub-clinical autism traits (ATs) in individuals drawn from a neurotypical population. The effect of stimulus inversion was also examined given that difficulties with processing inverted faces are thought …

Rapid Assessment Of Problem Solving For Kids (Raps-K), Hannah Perdew

Mahurin Honors College Capstone Experience/Thesis Projects

The Rapid Assessment of Problem Solving (RAPS) is a clinical assessment of verbal problem solving skills created by Dr. Robert Marshall and colleagues (Marshall, 2003). The assessment, originally developed for adults, is based on the well-known twenty questions game. The clinician administering the assessment chooses a target picture and the participant asks yes or no questions to eliminate incorrect answers and, eventually, identify the target picture. Question asking efficiency, indicated by the number of choices eliminated, is considered to reflect levels of cognitive functioning, specifically problem solving. Recently, the RAPS has been utilized with typically developing children and children with …

Maternal Immune Activation (Mia) In Mice: A Study To Phenotype Asd-Related Communication Behaviors And Analyze Maternal Health Outcomes In The Us, Komalpreet Gulati

Honors Scholar Theses

Core symptoms of Autism Spectrum Disorders (ASD) include deficits in social/communicative behaviors, and repetitive/stereotyped behaviors. Mouse models are a highly established paradigm used to study the phenotypic deficits that result from various inducible genotypic or environmental risk factors for ASD. Previous studies have demonstrated a link between maternal immune activation (MIA) and ASD-like behaviors in mouse models. In this model, the maternal immune system is activated during pregnancy by injecting the viral mimic poly(I:C). The resulting offspring are phenotyped and analyzed with regards to their communicative behaviors.

Previous studies have demonstrated that male pups born to dams with immune activation …

A Model Of Employment Supports For Job Seekers With Intellectual Disabilities, Alberto Migliore, Kelly Nye-Lengerman, Oliver Lyons, Jennifer Bose, John Butterworth, Thinkwork! At The Institute For Community Inclusion At Umass Boston

ThinkWork! Publications

Interviews with 16 employment consultants-triangulated with job seekers, family members, and supervisors-revealed a model of employment supports aligned with the elements described in the literature, although with an added emphasis on (a) building trust as a key element starting from day one; (b) a circular process converging on the job match; (c) and flexible intensity of supports. The model can be used for improving clarity in communication with employment consultants about effective employment support practices for assisting job seekers with intellectual and developmental disabilities.

Research Brief: "Service Delivery Experiences And Intervention Needs Of Military Families With Children With Asd", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This study describes the service delivery challenges and intervention needs of military families that include children with autism spectrum disorder (ASD) who have relocated. In practice and policy, military families with children with ASD living on a military base should consider serving as a mentor to new families on the base to offer information on schools and community resources, and would also benefit from the increased accessibility of resources by the Department of Defense (DoD). More research is needed to learn the best practices of service delivery for military families with children with ASD, and future studies on service delivery …

Exploring The Impact Of Community Service On Career Exploration, Self-Determination, And Social Skills For Transition-Age Youth With Autism Spectrum Disorders, Jaimie Ciulla Timmons, Agnes Zalewska, Allison C. Hall, Sheila Fesko, Thinkwork! At The Institute For Community Inclusion At Umass Boston

ThinkWork! Publications

Bleak transition outcomes for youth with autism spectrum disorder (ASD), coupled with the surge in incidence, has led to the need for focused and innovative transition strategies. While structured community service reveals promise, documentation of how community service experiences contribute to building employment skills for youth with intellectual/developmental disability (IDD), including those with ASD, is under-researched. The purpose of this paper is to explore the impact of a community service on employment skill-building for youth with ASD. Findings from 23 qualitative interviews with a range of stakeholders showed positive perceptions in the areas of career exploration, self-determination, and social skill …

Whose Expertise Is It? Evidence For Autistic Adults As Critical Autism Experts, Kristen Gillespie-Lynch, Steven K. Kapp, Patricia J. Brooks, Jonathan Pickens, Ben Schwartzman

Publications and Research

Autistic and non-autistic adults’ agreement with scientific knowledge about autism, how they define autism, and their endorsement of stigmatizing conceptions of autism has not previously been examined. Using an online survey, we assessed autism knowledge and stigma among 636 adults with varied relationships to autism, including autistic people and nuclear family members. Autistic participants exhibited more scientifically based knowledge than others. They were more likely to describe autism experientially or as a neutral difference, and more often opposed the medical model. Autistic participants and family members reported lower stigma. Greater endorsement of the importance of normalizing autistic people was associated …

How Useful Is Electroencephalography In The Diagnosis Of Autism Spectrum Disorders And The Delineation Of Subtypes: A Systematic Review, Oana Gurau, William Bosl, Charles R. Newton

Nursing and Health Professions Faculty Research and Publications

Autism spectrum disorders (ASD) are thought to be associated with abnormal neural connectivity. Presently, neural connectivity is a theoretical construct that cannot be easily measured. Research in network science and time series analysis suggests that neural network structure, a marker of neural activity, can be measured with electroencephalography (EEG). EEG can be quantified by different methods of analysis to potentially detect brain abnormalities. The aim of this review is to examine evidence for the utility of three methods of EEG signal analysis in the ASD diagnosis and subtype delineation. We conducted a review of literature in which 40 studies were …

Impaired Synaptic Development In A Maternal Immune Activation Mouse Model Of Neurodevelopmental Disorders, Pierluca Coiro, Ragunathan Padmashri, Anand Suresh, Elizabeth Spartz, Gurudutt Pendyala, Shinnyi Chou, Yoosun Jung, Brittney Meays, Shreya Roy, Nagsen Gautam, Yazen Alnouti, Ming Li, Anna Dunaevsky

Department of Psychology: Faculty Publications

Both genetic and environmental factors are thought to contribute to neurodevelopmental and neuropsychiatric disorders with maternal immune activation (MIA) being a risk factor for both autism spectrum disorders and schizophrenia. Although MIA mouse offspring exhibit behavioral impairments, the synaptic alterations in vivo that mediate these behaviors are not known. Here we employed in vivo multiphoton imaging to determine that in the cortex of young MIA offspring there is a reduction in number and turnover rates of dendritic spines, sites of majority of excitatory synaptic inputs. Significantly, spine impairments persisted into adulthood and correlated with increased repetitive behavior, an ASD relevant …

The Role Of Anger Rumination And Autism Spectrum Disorder– Linked Perseveration In The Experience Of Aggression In The General Population, Cara E. Pugliese, Matthew S. Fritz, Susan W. White

Department of Educational Psychology: Faculty Publications

This study (a) examined the role of anger rumination as a mediator of the relation between social anxiety and the experience of anger, hostility, and aggression, in the general population, and (b) evaluated the degree to which the presence of autism spectrum disorder characteristics moderates the indirect influence of anger rumination. We then explored whether social cognition and perseveration characteristic of autism spectrum disorder uniquely accounted for the predicted moderation. In this survey study of young adults (n = 948), anger rumination mediated the relation between social anxiety and hostility, as well as verbal and physical aggression, as predicted. Greater …

Anxiety Symptoms In Individuals With High Functioning Autism, Jane C. Kelleher

Honors Scholar Theses

Research indicates a complicated relationship between anxiety disorders and autism spectrum disorders (ASDs). The current study examined the relationship between anxiety symptoms and ASD in 30 Optimal Outcome (OO) individuals, 33 High Functioning Autism (HFA) individuals, and 34 Typically Developing (TD) individuals. The groups were compared on the K-SADS measure of anxiety symptoms. The HFA group presented greater anxiety than both the OO and TD groups, and the OO and TD groups only differed on one anxiety symptom. Across all three groups, there was a significant association between greater anxiety symptoms and a higher level of social and communicative impairment. …

Voices Of Young Adults With Autism And Their Perspective On Life Choices After Secondary Education, Susan Galler

Doctoral Dissertations and Projects

The purpose of this phenomenological qualitative research study was to explore how young adults who have an autism spectrum disorder perceive their life choices after secondary education. The focus participants in the sample were young adults with Autism Spectrum Disorder (ASD). For the purpose of this research, ASD includes autism and Asperger's Disorder. Participants between the ages of 18 and 33 were located through purposive sampling in the states of Minnesota and Tennessee, as the author has previously worked in these states. Participants were asked five open ended focus questions during the span of two face to face interviews. Questions …

Out Of The Mouths Of Babes: Vocal Production In Infant Siblings Of Children With Asd, Rhea Paul, Yael Fuerst, Gordon Ramsay, Kasia Chawarska, Ami Klin

Communication Disorders Faculty Publications

Background: Younger siblings of children with autism spectrum disorders (ASD) are at higher risk for acquiring these disorders than the general population. Language development is usually delayed in children with ASD. The present study examines the development of pre-speech vocal behavior in infants at risk for ASD due to the presence of an older sibling with the disorder. Methods: Infants at high risk (HR) for ASD and those at low risk, without a diagnosed sibling (LR), were seen at 6, 9, and 12 months as part of a larger prospective study of risk for ASD in infant siblings. Standard clinical …

Joint Attention In Young Children With Autism, Sabrina Jara

Honors Scholar Theses

Autism spectrum disorders (ASDs) are classified as pervasive developmental disorders characterized by social, communicative, and behavioral impairments. According to formal and informal reports, children with ASD present with receptive and expressive language delay. Joint attention (JA: the behavior that occurs when two individuals focus on the same object or event) has been identified as a possible marker of delayed language development in children with ASD. In this study, the JA behaviors in children with ASD were contrasted with initially language-matched typically developing (TYP) children across three visits.

Measures of language, the frequency, duration, and source of initiation of JA episodes, …