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A Role Of The Basal Ganglia In Movement: The Effect Of Precues On Discrete Bi-Directional Movements In Parkinson's Disease, Andrew Johnson, Philip Vernon, Quincy Almeida, Linda Grantier, Mandar Jog
A Role Of The Basal Ganglia In Movement: The Effect Of Precues On Discrete Bi-Directional Movements In Parkinson's Disease, Andrew Johnson, Philip Vernon, Quincy Almeida, Linda Grantier, Mandar Jog
Andrew M. Johnson
The effect of a precue on improving movement initiation (i.e., reaction time; RT) is well understood, whereas its influence on movement execution (i.e., movement time; MT) has rarely been examined. The current study investigated the influence of a directional precue (i.e., left vs. right) on the RT and MT of simple and discrete bi-directional movements in a large sample of Parkinson's disease patients and healthy control participants. Both patients and controls were tested twice, with testing sessions separated by 2 hours. Patients were tested first following an overnight levodopa withdrawal and again after they had taken their medication. Both patients …