Medicine and Health Sciences Commons^™

Research Brief: "Psychopathology, Iraq And Afghanistan Service, And Suicide Among Veterans Health Administration Patients", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the connections between being a OIF/OEF veteran who receives care from the VHA and suicide mortality. In policy and practice, mental health screenings for OIF/OEF veterans should be implemented in non-VHA healthcare settings and families of OIF/OEF veterans should encourage veterans to seek treatment if they exhibit signs of a mental health condition. The VHA should implement policies that promote its healthcare to veterans in order to decrease suicide risks among veterans and should also offer more mental health screenings for recently returned veterans. Suggestions for future research include looking at risks for suicide after traumatic …

Interpersonal Identity Formation In Conversations With Close Friends About Dating Relationships, Elizabeth M. Morgan, Neill Korobov

Psychological Sciences Faculty Publications and Presentations

The present study explores how close same-sex friendship groups participate in the co-construction of identities in the interpersonal domain during young adulthood. Participants included 24 same-sex college student friendship triads (12 male and 12 female; 72 total participants) who took part in semi-structured group interviews that elicited stories about conversations with their friends about dating relationship problems. Qualitative thematic analysis revealed five common responses to dating problems evidencing identity work in the context of friends' conversations. These responses included relating the issue to one's own experiences, providing validation and encouragement, joking about the problem, offering advice, and providing concrete instrumental …

Septohippocampal Gabaergic Neurons Mediate The Altered Behaviors Induced By N-Methyl-D-Aspartate Receptor Antagonists., Jingyi Ma, Siew Kian Tai, L Stan Leung

Physiology and Pharmacology Publications

We hypothesize that selective lesion of the septohippocampal GABAergic neurons suppresses the altered behaviors induced by an N-methyl-D-aspartate (NMDA) receptor antagonist, ketamine or MK-801. In addition, we hypothesize that septohippocampal GABAergic neurons generate an atropine-resistant theta rhythm that coexists with an atropine-sensitive theta rhythm in the hippocampus. Infusion of orexin-saporin (ore-SAP) into the medial septal area decreased parvalbumin-immunoreactive (GABAergic) neurons by ~80%, without significantly affecting choline-acetyltransferase-immunoreactive (cholinergic) neurons. The theta rhythm during walking, or the immobility-associated theta induced by pilocarpine, was not different between ore-SAP and sham-lesion rats. Walking theta was, however, more disrupted by atropine sulfate in ore-SAP than …

Do Social Conditions Affect Capuchin Monkeys' (Cebus Apella) Choices In A Quantity Judgment Task?, Michael J. Beran, Bonnie M. Perdue, Audrey E. Parrish, Theodore A. Evans

Language Research Center

Beran et al. (2012) reported that capuchin monkeys closely matched the performance of humans in a quantity judgment test in which information was incomplete but a judgment still had to be made. In each test session, subjects first made quantity judgments between two known options. Then, they made choices where only one option was visible. Both humans and capuchin monkeys were guided by past outcomes, as they shifted from select- ing a known option to selecting an unknown option at the point at which the known option went from being more than the average rate of return to less than …

Defining The Developmental Parameters Of Temper Loss In Early Childhood: Implications For Developmental Psychopathology, Heide Hullsiek, Margaret J. Briggs-Gowan

UCHC Articles - Research

Abstract

Background

Temper modulation problems are both a hallmark of early childhood and a common mental health concern. Thus, characterizing specific behavioral manifestations of temper loss along a dimension from normative misbehaviors to clinically significant problems is an important step toward identifying clinical thresholds.

Methods

Parent-reported patterns of temper loss were delineated in a diverse community sample of preschoolers (n = 1,490). A developmentally sensitive questionnaire, the Multidimensional Assessment of Preschool Disruptive Behavior (MAP-DB), was used to assess temper loss in terms of tantrum features and anger regulation. Specific aims were: (a) document the normative distribution of temper loss in …

The Buried In Treasures Workshop: Waitlist Control Trial Of Facilitated Support Groups For Hoarding, Randy O. Frost, Dylan Ruby, Lee J. Shuer

Psychology: Faculty Publications

Hoarding is a serious form of psychopathology that has been associated with significant health and safety concerns, as well as the source of social and economic burden (Tolin, Frost, Steketee, & Fitch, 2008; Tolin, Frost, Steketee, Gray, & Fitch, 2008). Recent developments in the treatment of hoarding have met with some success for both individual and group treatments. Nevertheless, the cost and limited accessibility of these treatments leave many hoarding sufferers without options for help. One alternative is support groups that require relatively few resources. Frost, Pekareva-Kochergina, and Maxner (2011) reported significant declines in hoarding symptoms following a non-professionally run …

Methods Of Screening To Detect Postpartum Depression, Anna Elliot, Shelby Young

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Postpartum depression is a mood altering condition that affects 10-20% of women after childbirth. Symptoms include an inability to perform activities of daily living, feelings of inadequacy/worthlessness, a discouraged outlook on life, altered sleeping pattern, overall worried feelings, and exhaustion. Screening is better than normal routine care in detecting postpartum depression, but only a small percentage of women are receiving screening. The focus of this study is to find the better evidence-based screening practice for nurses to detect postpartum depression: the Edinburgh Postnatal Depression Scale (EPDS) or the Postpartum Depression Screening Scale (PDSS).

The Therapeutical Benefits Of Using Music Therapy Rather Than Cognitive Therapy In Depressed Older Adults In A Healthcare Setting, Brittnie Jarrett, Elizabeth Hansel

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Limited research has been conducted concerning the effects of music therapy in depressed individuals with dementia. Music therapy is a simple, non-invasive, and inexpensive treatment in relation to pharmaceutical interventions and possibly even some forms of cognitive therapies. Depression, a disabling disease that can cause a reduction in quality of life and loss of general functioning, affects more than 6.5 million of the 35 million Americans aged 65 years or older. 74% of older adults remain depressed one year after general treatment with pharmaceutical agents.

The Role Of Domain Satisfaction In Explaining The Paradoxical Association Between Life Satisfaction And Age, Kimberly K. Mcadams, Richard E. Lucas, M. Brent Donnellan

Psychological Sciences Faculty Publications and Presentations

Although aging is associated with declines in many life circumstances, overall life satisfaction does not appear to sharply decline with age. One explanation for this paradoxical finding is that several life domains improve with age such that increases in certain domains balance the decreases in others. Life and domain satisfaction data from eight years of the British Household Panel Study were analyzed to evaluate this hypothesis. Results showed that although domain satisfaction scores demonstrate distinct trajectories, the aggregate of these distinct trajectories resembled the overall life satisfaction trajectory. These findings have implications for top-down and bottom-up models of life satisfaction.

An Integrative Review Of Out-Patient Teaching For Children With Attention Deficit Hyperactivity Disorder, Elizabeth Hicks, Melissa Hogan, Kendra Parker

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Attention deficit hyperactivity disorder is most prevalent in children. Symptoms include inappropriate levels of hyperactivity, impulsive behavior, and lack of attention. 3-9% of children suffer from the symptoms of ADHD. Treatments of ADHD vary: pharmacological therapy includes stimulants and non-stimulants, whereas non-pharmacological treatments include restriction diet, nutrient supplements, and psychosocial interventions. Psycho-stimulant treatment is not beneficial for 20-30% of children with ADHD. The purpose of this study is to determine if diet/nutrition and parent training treatments are effective in managing the symptoms of children with ADHD.

Reintegration Of Child Soldiers In Burundi: A Tracer Study, Mark J.D. Jordans, Ivan H. Komproe, Wietse A. Tol, Aline Ndayisaba, Theodora Nisabwe, Brandon A. Kohrt

Psychiatry and Behavioral Sciences Faculty Publications

Background

Substantial attention and resources are aimed at the reintegration of child soldiers, yet rigorous evaluations are rare.

Methods

This tracer study was conducted among former child soldiers (N=452) and never-recruited peers (N=191) who participated in an economic support program in Burundi. Socio-economic outcome indicators were measured retrospectively for the period before receiving support (T1; 2005–06); immediately afterwards (T2; 2006–07); and at present (T3; 2010). Participants also rated present functional impairment and mental health indicators.

Results

Participants reported improvement on all indicators, especially economic opportunity and social integration. At present no difference existed between both groups on any of the …

Measuring Group Synchrony: A Cluster-Phase Method For Analyzing Multivariate Movement Time-Series, Michael J. Richardson, Randi L. Garcia, Till D. Frank, Madison Gergor, Kerry L. Marsh

Psychology: Faculty Publications

A new method for assessing group synchrony is introduced as being potentially useful for objectively determining degree of group cohesiveness or entitativity. The cluster-phase method of Frank and Richardson (2010) was used to analyze movement data from the rocking chair movements of six-member groups who rocked their chairs while seated in a circle facing the center. In some trials group members had no information about others’ movements (their eyes were shut) or they had their eyes open and gazed at a marker in the center of the group. As predicted, the group level synchrony measure was able to distinguish between …

Research Brief: "Impact Of The Seeking Safety Program On Clinical Outcomes Among Homeless Female Veterans With Psychiatric Disorders", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the effect of the Seeking Safety program's services on improvement in PTSD, psychiatric symptoms, and social support among homeless female veterans. In policy and practice, clinicians should be trained on how to use the program to better serve homeless female veterans, and policymakers should push for clinician training for those who work with homeless veterans. Suggestions for future research include applying this study and the Seeking Safety program to non-VA healthcare systems, assessing substance use within the program, and assessing the long-term effects of the Seeking Safety program.

Optimal Management For People With Severe Spasticity, Jeffrey S. Shilt, Pennie S. Seibert, Vivek Kadyan

Psychological Sciences Faculty Publications and Presentations

Spasticity is characterized by velocity-dependent increase in tonic stretch reflexes and tendon jerks. Many people affected by spasticity receive late treatment, or no treatment, which greatly reduces the potential to regain full motor control and restore function. There is much to consider before determining treatment for people with spasticity. Treatment of pediatric patients increases the complexity, because of the substantial difference between adult and pediatric spasticity. Proper patient evaluation, utilization of scales and measures, and obtaining patient and caregiver history is vital in determining optimal spasticity treatment. Further, taking into consideration the limitations and desires of individuals serve as a …

Osmd: Cultural Competence Tool For Research, Education, And Practice, Rebecca L. Tadlock-Marlo, Danny Applegate

Faculty Research & Creative Activity

Results from a mixed methods study provide insight into redefining multicultural counseling competencies specific to school counselors. Foci include new counseling competencies and implications for counselor educators. Attendees will explore aspects of multiculturalism, counseling competencies of school counselors, research implications, and its importance for the field. Also discussed will be applying information to the development of skills, knowledge, and awareness of counselors-in-training through specific pedagogical examples. Participant discussion is vital to this presentation to further discuss content area, explore redefining multiculturalism, and implications this research has for both practicing counselors and counselor educators. Attendees can expect to gain groundbreaking theory …

Molecular Pathway Reconstruction And Analysis Of Disturbed Gene Expression In Depressed Individuals Who Died By Suicide, Vladimir Zhurov, John D. H. Stead, Zul Merali, Miklos Palkovits, Gabor Faludi, Caroline Schild-Poulter, Hymie Anisman, Michael O. Poulter

Brain and Mind Institute

Molecular mechanisms behind the etiology and pathophysiology of major depressive disorder and suicide remain largely unknown. Recent molecular studies of expression of serotonin, GABA and CRH receptors in various brain regions have demonstrated that molecular factors may contribute to the development of depressive disorder and suicide behaviour. Here, we used microarray analysis to examine the expression of genes in brain tissue (frontopolar cortex) of individuals who had been diagnosed with major depressive disorder and died by suicide, and those who had died suddenly without a history of depression. We analyzed the list of differentially expressed genes using pathway analysis, which …

Accuracy Of Self-Reported Sun Exposure And Sun Protection Behavior, Joel J. Hillhouse, Robert Turrisi, James Jaccard, June K. Robinson

ETSU Faculty Works

The objective of this study was to compare the accuracy of self-reported skin cancer risk outcome measures proposed as standards by prevention experts to aggregated estimates of behavior from weekly diaries. Weekly electronic diaries of ultraviolet radiation (UVR) behaviors, initially validated by comparison with daily electronic diaries, were used to assess the accuracy of commonly used end-of-summer self-reported measures among 250 adults. Results revealed low biases, and good correspondence between simple open-ended self-reported estimates of days outside, hours outside, sunbathing days and hours, and days outside when not protected by either sunscreen, long-sleeved shirts, hats, or shade. Rating scale measures …

Randomized Clinical Trial Of Cognitive Behavioral Therapy (Cbt) Versus Acceptance And Commitment Therapy (Act) For Mixed Anxiety Disorders, Joanna Arch, Georg Eifert, Carolyn Davies, Jennifer C. Plumb Vilardaga, Raphael D. Rose, Michael G. Craske

Psychology Faculty Articles and Research

Objective—Randomized comparisons of acceptance-based treatments with traditional cognitive behavioral therapy (CBT) for anxiety disorders are lacking. To address this research gap, we compared acceptance and commitment therapy (ACT) to CBT for heterogeneous anxiety disorders.

Method—One hundred twenty eight individuals (52% female, mean age = 38, 33% minority) with one or more DSM-IV anxiety disorders began treatment following randomization to 12 sessions of CBT or ACT; both treatments included behavioral exposure. Assessments at pre-treatment, post-treatment, 6-month, and 12-month follow-up measured anxiety specific (principal disorder Clinical Severity Ratings [CSR], Anxiety Sensitivity Index, Penn State Worry Questionnaire, Fear Questionnaire avoidance) and …

Research Brief: "Web-Based Post-Traumatic Stress Disorder Education For Military Family Members", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

In this study, researchers introduced an educational website to assess and improve knowledge of PTSD, and also help to engage family members in positive actions to assist service members struggling with PTSD. Web-based content can serve as a valuable method of providing care and information to military service members without the risk of being stigmatized; therefore, policy makers should focus on creating and maintaining structural and financial support for programs that provide military service members, and their families, tools to manage post-deployment issues. Future studies should focus on providing an increased range of services for military families using the educational …

Impact Of Sunlight On The Age Of Onset Of Bipolar Disorder, Michael Bauer, Tasha Glenn, Martin Alda, Ole A. Andreassen, Raffaella Ardau, Frank Bellivier, Michael Berk, Thomas D. Bjella, Letizia Bossini, Maria Del Zompo, Seetal Dodd, Andrea Fagiolini, Mark A. Frye, Ana Gonzalez-Pinto, Chantal Henry, Flávio Kapczinkski, Sebastian Kliwicki, Barbara König, Mauricio Kunz, Beny Lafer, Carlos Lopez-Jaramillo, Mirko Manchia, Wendy Marsh, Monica Martinez-Cengotitabengoa, Ingrid Melle, Gunnar Morken, Rodrigo Munoz, Fabiano G. Nery, Claire O'Donovan, Andrea Pfennig, Danilo Quiroz, Natalie Rasgon, Andreas Reif, Janusz Rybakowski, Kemal Sagduyu, Christian Simhandi, Carla Torrent, Eduard Vieta, Mark Zetin, Peter C. Whybrow

Marriage and Family Therapy Faculty Articles and Research

Objective: Although bipolar disorder has high heritability, the onset occurs during several decades of life, suggesting that social and environmental factors may have considerable influence on disease onset. This study examined the association between the age of onset and sunlight at the location of onset.

Method: Data were obtained from 2414 patients with a diagnosis of bipolar I disorder, according to DSM-IV criteria. Data were collected at 24 sites in 13 countries spanning latitudes 6.3 to 63.4 degrees from the equator, including data from both hemispheres. The age of onset and location of onset were obtained retrospectively, from …

Prospective Analysis Of Early Lapse To Drinking And Smoking Among Individuals In Concurrent Alcohol And Tobacco Treatment [Post-Print], Laura Holt

Faculty Scholarship

The aims of the current study were to examine, prospectively, (a) dynamic changes in affective state, self-efficacy, and urge in the hours before initial smoking and drinking lapses among individuals in concurrent alcohol and smoking treatment, and (b) the extent to which self-efficacy, urge to use, and/or the use of one substance predicted lapse to the other substance. Ninety-six men and women recruited for a clinical trial of concurrent alcohol and tobacco treatment were eligible for inclusion. Only data from those who experienced an initial lapse to drinking (n = 29) or smoking (n = 32) were included. Two outpatient …

Taking The Perspective That A Depressive State Reflects Inflammation: Implications For The Use Of Antidepressants, Jill Littrell

SW Publications

This paper reviews both the evidence that supports the characterization of depression as an inflammatory disorder and the different biochemical mechanisms that have been postulated for the connection between inflammation and depression. This association offers credible explanation for the short term efficacy of antidepressants, which have short term anti-inflammatory effects. Evidence for those anti-inflammatory effects is discussed. Evidence of the contrary long-term effects of antidepressants, which increase rather than decrease inflammation, is also reviewed. It is argued that this increase in inflammation would predict an increase in chronicity among depressed patients that have been treated with antidepressants drugs, which has …

Psychosocial Vulnerabilities To Depression After Acute Coronary Syndrome: The Pivotal Role Of Rumination In Predicting And Maintaining Depression, Ellen-Ge Denton, Nina Rieckmann, Karina W. Davidson, William F. Chaplin

Publications and Research

Psychosocial vulnerabilities may predispose individuals to develop depression after a significant life stressor, such as an acute coronary syndrome (ACS).The aims are (1) to examine the interrelations among vulnerabilities, and their relation with changes in depressive symptoms 3 months after ACS, (2) to prospectively assess whether rumination interacts with other vulnerabilities as a predictor of later depressive symptoms, and (3) to examine how these relations differ between post-ACS patients who meet diagnostic criteria for depression at baseline versus patients who do not. Within 1week after hospitalization for ACS, and again after 3 months, 387 patients (41% female, 79.6% white, mean …

Opinion: Bias Is Unavoidable, Lisa Cosgrove

Counseling and School Psychology Faculty Publication Series

It is part of the human condition to have implicit biases—and remain blissfully ignorant of them. Academic researchers, scientists, and clinicians are no exception; they are as marvelously flawed as everyone else. But it is not the cognitive bias that’s the problem. Rather, the denial that there is a problem is where the issues arise. Indeed, our capacity for self-deception was beautifully captured in the title of a recent book addressing researchers’ self-justificatory strategies, Mistakes Were Made (But Not by Me).

Examining The Association Between Psychiatric Illness And Suicidal Ideation In A Sample Of Treatment-Seeking Canadian Peacekeeping And Combat Veterans With Posttraumatic Stress Disorder, Don Richardson, Kate St. Cyr, Alexandra M. Mcintyre-Smith, David Haslam, Jon D. Elhai, Jitender Sareen

MacDonald Franklin OSI Research Centre

Objective:

Our study examines the association between suicidal ideation and and self-reported symptoms of posttraumatic stress disorder (PTSD), major depressive disorder (MDD), generalized anxiety disorder (GAD), and alcohol use disorder (AUD) in a sample of treatment-seeking Canadian combat and peacekeeping veterans; and identifies potential predictors of suicidal ideation.

Methods:

Actively serving Canadian Forces and Royal Canadian Mounted Police members and veterans seeking treatment at the Parkwood Hospital Operational Stress Injury Clinic (n = 250) completed measures including the Primary Care Evaluation of Mental Disorders Patient Health Questionnaire, the Alcohol Use Disorder Identification Test, and the PTSD Checklist—Military Version (PCL-M) …

Parametric Studies Of Antipsychotic-Induced Sensitization In The Conditioned Avoidance Response Model: Roles Of Number Of Drug Exposure, Drug Dose, And Test–Retest Interval, Natashia Swalve, Ming Li

Department of Psychology: Faculty Publications

Repeated haloperidol and olanzapine treatment produces an enhanced disruption of avoidance responding, a validated measure of antipsychotic activity. Experimental parameters affecting this sensitization-like effect have not been thoroughly examined. The present study investigated the role of three parameters (number of injections, dose, and interval between initial exposure and challenge) in antipsychotic sensitization in the conditioned avoidance response paradigm. Well-trained Sprague–Dawley rats received different numbers of drug treatment (1–5 days) or different doses of haloperidol (0.025–0.10 mg/kg, subcutaneously) or olanzapine (0.5–2.0 mg/kg, subcutaneously). After certain time intervals (4, 10 or 17 days), they were tested for the expression of haloperidol or …

Neural Basis Of The Potentiated Inhibition Of Repeated Haloperidol And Clozapine Treatment On The Phencyclidine-Induced Hyperlocomotion, Changjiu Zhao, Tao Sun, Ming Li

Department of Psychology: Faculty Publications

Clinical observations suggest that antipsychotic effect starts early and increases progressively over time. This time course of antipsychotic effect can be captured in a rat phencyclidine (PCP)-induced hyperlocomotion model, as repeated antipsychotic treatment progressively increases its inhibition of the repeated PCP-induced hyperlocomotion. Although the neural basis of acute antipsychotic action has been studied extensively, the system that mediates the potentiated effect of repeated antipsychotic treatment has not been elucidated. In the present study, we investigated the neuroanatomical basis of the potentiated action of haloperidol (HAL) and clozapine (CLZ) treatment in the repeated PCP-induced hyperlocomotion. Once daily for five consecutive days, …

Neural Mechanisms Of Decision Making In Hoarding Disorder, David F. Tolin, Michael C. Stevens, Anna L. Villavicencio, Melissa M. Norberg, Vince D. Calhoun, Randy O. Frost, Gail Steketee, Scott L. Rauch, Godfrey D. Pearlson

Psychology: Faculty Publications

Context: Hoarding disorder (HD), previously considered a subtype of obsessive-compulsive disorder (OCD), has been proposed as a unique diagnostic entity in DSM-5. Current models of HD emphasize problems of decision-making, attachment to possessions, and poor insight, whereas previous neuroimaging studies have suggested abnormalities in frontal brain regions. Objective: To examine the neural mechanisms of impaired decision making in HD in patients with well-defined primary HD compared with patients with OCD and healthy control subjects (HCs). Design: We compared neural activity among patients with HD, patients with OCD, and HCs during decisions to keep or discard personal possessions and control possessions …

Hcv Behavioral Health Preparation Of The Racial/Ethnic Minority: Measurement Development Of A Hcv Treatment Readiness Tool In Spanish And English, Michele Vella, Joseph L. Yozviak Do, Facp, Judith Lash Rn

Department of Medicine

No abstract provided.

Sleep Hygiene And Problem Behaviors In Snoring And Non- Snoring School-Age Children, Lisa A. Witcher, David Gozal, Dennis L. Molfese, Scott M. Salathe, Karen Spruyt, Valerie Mclaughlin Crabtree

Center for Brain, Biology, and Behavior: Faculty and Staff Publications

Objectives—The effects of sleep-disordered breathing, sleep restriction, dyssomnias, and parasomnias on daytime behavior in children have been previously assessed. However, the potential relationship(s) between sleep hygiene and children’s daytime behavior remain to be explored. The primary goal of this study was to investigate the relationship between sleep hygiene and problematic behaviors in non-snoring and habitually snoring children.

Methods—Parents of 100 5- to 8-year-old children who were reported to snore “frequently” to “almost always,” and of 71 age-, gender-, and ethnicity-matched children who were reported to never snore participated in this study. As part of a larger, ongoing study, …