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Full-Text Articles in Medicine and Health Sciences

Intraminority Solidarity: The Role Of Critical Consciousness, Esther Burson, Erin B. Godfrey Oct 2020

Intraminority Solidarity: The Role Of Critical Consciousness, Esther Burson, Erin B. Godfrey

Psychology: Faculty Publications

A central question in the growing field of intraminority relations is how best to promote solidarity among marginalized groups. The current article reviews existing social psychological theories of intraminority relations, with a focus on barriers to, and facilitators of, intraminority solidarity. In particular, we explore the roles of competition and identity threats in eroding solidarity, and examine how similarity perceptions, a common identity of stigma, and structural and historical attributions generate solidarity. We then suggest that critical consciousness, a theory of sociopolitical development prominent in the developmental and community psychology literatures, can integrate disparate findings and extend our understanding of …


Nobiletin Affects Circadian Rhythms And Oncogenic Characteristics In A Cell-Dependent Manner, Sujeewa S. Lellupitiyage Don, Kelly L. Robertson, Hui-Hsien Lin, Caroline Labriola, Mary E. Harrington, Stephanie R. Taylor, Michelle E. Farkas Jul 2020

Nobiletin Affects Circadian Rhythms And Oncogenic Characteristics In A Cell-Dependent Manner, Sujeewa S. Lellupitiyage Don, Kelly L. Robertson, Hui-Hsien Lin, Caroline Labriola, Mary E. Harrington, Stephanie R. Taylor, Michelle E. Farkas

Psychology: Faculty Publications

The natural product nobiletin is a small molecule, widely studied with regard to its therapeutic effects, including in cancer cell lines and tumors. Recently, nobiletin has also been shown to affect circadian rhythms via their enhancement, resulting in protection against metabolic syndrome. We hypothesized that nobiletin’s anti-oncogenic effects, such as prevention of cell migration and formation of anchorage independent colonies, are correspondingly accompanied by modulation of circadian rhythms. Concurrently, we wished to determine whether the circadian and anti-oncogenic effects of nobiletin differed across cancer cell lines. In this study, we assessed nobiletin’s circadian and therapeutic characteristics to ascertain whether these …


Circada: Shiny Apps For Exploration Of Experimental And Synthetic Circadian Time Series With An Educational Emphasis, Lisa Cenek, Liubou Klindziuk, Cindy Lopez, Eleanor Mccartney, Blanca Martin Burgos, Selma Tir, Mary E. Harrington, Tanya L. Leise Apr 2020

Circada: Shiny Apps For Exploration Of Experimental And Synthetic Circadian Time Series With An Educational Emphasis, Lisa Cenek, Liubou Klindziuk, Cindy Lopez, Eleanor Mccartney, Blanca Martin Burgos, Selma Tir, Mary E. Harrington, Tanya L. Leise

Psychology: Faculty Publications

Circadian rhythms are daily oscillations in physiology and behavior that can be assessed by recording body temperature, locomotor activity, or bioluminescent reporters, among other measures. These different types of data can vary greatly in waveform, noise characteristics, typical sampling rate, and length of recording. We developed 2 Shiny apps for exploration of these data, enabling visualization and analysis of circadian parameters such as period and phase. Methods include the discrete wavelet transform, sine fitting, the Lomb-Scargle periodogram, autocorrelation, and maximum entropy spectral analysis, giving a sense of how well each method works on each type of data. The apps also …


Deconstructing Circadian Disruption: Assessing The Contribution Of Reduced Peripheral Oscillator Amplitude On Obesity And Glucose Intolerance In Mice, Vincent Van Der Vinne, Blanca Martin Burgos, Mary E. Harrington, David R. Weaver Mar 2020

Deconstructing Circadian Disruption: Assessing The Contribution Of Reduced Peripheral Oscillator Amplitude On Obesity And Glucose Intolerance In Mice, Vincent Van Der Vinne, Blanca Martin Burgos, Mary E. Harrington, David R. Weaver

Psychology: Faculty Publications

Disturbing the circadian regulation of physiology by disruption of the rhythmic environment is associated with adverse health outcomes but the underlying mechanisms are unknown. Here, the response of central and peripheral circadian clocks to an advance or delay of the light-dark cycle was determined in mice. This identified transient damping of peripheral clocks as a consequence of an advanced light-dark cycle. Similar depression of peripheral rhythm amplitude was observed in mice exposed to repeated phase shifts. To assess the metabolic consequences of such peripheral amplitude depression in isolation, temporally chimeric mice lacking a functional central clock (Vgat-Cre+ Bmal1fl/fl) were housed …


Community Characteristics, Victimization, And Psychological Adjustment Among School-Aged Adopted Children With Lesbian, Gay, And Heterosexual Parents, Abbie E. Goldberg, Randi L. Garcia Mar 2020

Community Characteristics, Victimization, And Psychological Adjustment Among School-Aged Adopted Children With Lesbian, Gay, And Heterosexual Parents, Abbie E. Goldberg, Randi L. Garcia

Psychology: Faculty Publications

Little research has examined victimization among school-aged children raised in lesbian/gay (LG) parent households and almost no work has attended to the school and community contexts that may impact their victimization risk. This study examined predictors of parent-reported child victimization and child adjustment, and parent responses to victimization, in 43 two-mother, 37 two-father, and 56 mother–father families, with adopted children (median age = 8.6 years). Predictors included parent (sexual orientation), school (climate, public versus private) and community (urbanicity, percentage voted Democrat) factors, with parent and child demographics included as controls. A total of 47% of parents reported one or more …


From Urges To Action: Negative Urgency And Nonsuicidal Self-Injury In An Acute Transdiagnostic Sample, Andrew D. Peckham, Haley Jordan, Alexandra Silverman, Stephanie Jarvi Steele, Theöstur Björgvinsson, Courtney Beard Jan 2020

From Urges To Action: Negative Urgency And Nonsuicidal Self-Injury In An Acute Transdiagnostic Sample, Andrew D. Peckham, Haley Jordan, Alexandra Silverman, Stephanie Jarvi Steele, Theöstur Björgvinsson, Courtney Beard

Psychology: Faculty Publications

Urgency–rash action during strong emotion–is a robust correlate of nonsuicidal self-injury (NSSI). This study tested whether urgency is associated with time between NSSI urges and NSSI, and sought to replicate the finding that urgency is associated with NSSI history. Participants attending a partial hospitalization program (N = 669) completed self-report measures of urgency, NSSI history and latency, and psychiatric symptoms. Consistent with previous research in clinical samples, rates of lifetime engagement in NSSI were high. Using logistic regression to predict short vs. long latency between urges and NSSI, no significant relationship emerged between negative urgency and latency to self-injure. Negative …