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- Cortical thickness (1)
- First-episode psychosis (1)
- Gut-brain axis (1)
- Habituation (1)
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- Hierarchical cluster analysis (1)
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- Rodent model of autism spectrum disorder (1)
- Schizophrenia (1)
- Social and non-social odours (1)
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Articles 1 - 4 of 4
Full-Text Articles in Medicine and Health Sciences
Data-Driven Neuroanatomical Subtypes In Various Stages Of Schizophrenia: Linking Cortical Thickness, Glutamate, And Language Functioning, Liangbing Liang
Data-Driven Neuroanatomical Subtypes In Various Stages Of Schizophrenia: Linking Cortical Thickness, Glutamate, And Language Functioning, Liangbing Liang
Electronic Thesis and Dissertation Repository
The considerable variation in the spatial distribution of cortical thickness changes has been used to parse heterogeneity in schizophrenia. We aimed to recover a ‘cortical impoverishment’ subgroup with widespread cortical thinning. We applied hierarchical cluster analysis to cortical thickness data of three datasets in different stages of psychosis and studied the cognitive, functional, neurochemical, language and symptom profiles of the observed subgroups. Our consensus-based clustering procedure consistently produced a subgroup characterized by significantly lower cortical thickness. This ‘cortical impoverishment’ subgroup was associated with a higher symptom burden in a clinically stable sample and higher glutamate levels with language impairments in …
Internet-Delivered Cognitive Behavioural Therapy For People With Mild Traumatic Brain Injury: A Feasibility Study, Ujjoyinee France Barua
Internet-Delivered Cognitive Behavioural Therapy For People With Mild Traumatic Brain Injury: A Feasibility Study, Ujjoyinee France Barua
Electronic Thesis and Dissertation Repository
Individuals with mild traumatic brain injury (mTBI) can experience high levels of emotional distress, leading to decreased quality of life and increased health care costs. Bowen's feasibility framework was used to examine the feasibility, acceptability, and limited efficacy of an innovative clinician-guided internet-delivered cognitive behavioural therapy program (ICBT) specialized for people with mTBI to improve their wellbeing. The data illustrated strong adherence and program satisfaction from participants. Likewise, statistically and clinically significant changes in symptoms of unhappiness and anxiety were found, along with improved self-efficacy and quality of life. The findings of this study contribute new knowledge to the emerging …
The Effect Of Propionic Acid On The Habituation To Social And Non-Social Odour Cues In Adult Male Rats, Cashmeira-Dove P. Tyson
The Effect Of Propionic Acid On The Habituation To Social And Non-Social Odour Cues In Adult Male Rats, Cashmeira-Dove P. Tyson
Electronic Thesis and Dissertation Repository
The enteric bacterial metabolite, propionic acid (PPA), elicits physiological and behavioural changes in rodents reminiscent of autism spectrum disorder (ASD). This includes abnormal sensory processing and social behaviour. ASD may contribute to social deficits through impaired habituation; therefore, the present study examined the effects of intraperitoneal PPA on the habituation to social and non-social odours. Adult male rats were injected daily with PPA or the vehicle control, and for 3 days, habituated to a conspecific odour or vanilla extract for 10 minutes. On day 4, rats were exposed to a novel conspecific odour or almond extract for 10 minutes to …
The Experience Of Mindfulness And Its Nondual Nature In Active Practitioners, Benjamin Tran
The Experience Of Mindfulness And Its Nondual Nature In Active Practitioners, Benjamin Tran
Electronic Thesis and Dissertation Repository
Mindfulness-based interventions have become well-established in the literature as an effective treatment for various health issues. Its application in psychology is predominantly informed by dualism; however, according to its Eastern traditions, a true understanding of mindfulness is developed via nondualistic ontological experiences that emerge in a mindfulness state. The purpose of this study was to explore the experience of mindfulness and its nondual nature as it is experienced in the world. Hermeneutical phenomenology, informed by an interpretivist lens, was employed. A sample of 13 mindfulness practitioners were individually interviewed. The experience of mindfulness and its nondual nature was considered through …