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The Impact Of A Naturalistic Stressor On Spontaneous Alternation Behavior: A New Animal Model Of Ocd, Christina Finch

Behavioral Neuroscience Honors Papers

Over the past few decades, various animal models of obsessive compulsive disorder (OCD) have been developed. Similarly, various stressors have been used throughout animal research. The Spontaneous Alternation Behavioral (SAB) model is a well-established model of OCD while 2,5-dihydro-2,4,5-trimethylthiazoline (TMT) has recently become a popular naturalistic stressor. This study linked the two together, thus modeling the effect of stress on OCD behaviors. After living in an enriched or standard environment for 3 weeks, male Sprague-Dawley rats were exposed to either TMT or no odor, and then were examined in the SAB task. Unlike what was hypothesized, the enriched environment proved …