Medicine and Health Sciences Commons^™

Nonmedical Stimulant Use In An Undergraduate College Student Sample: Demographics, Academics, Stress, And Other Substance Use, Ashley Skye Vanover, Meredith K. Ginley, Shelby Whalan

Undergraduate Honors Theses

Nonmedical use of prescription stimuluants (NMUS) can cause adverse outcomes for college students including academic impediments, such as a lowered GPA, and polyuse of illicit substances (Garcia et al., 2021; Holt & McCarthy, 2019; Norman & Ford, 2018). The current study investigated the demographics, academics, stress, and polysubstance use between students who endorsed NMUS and those who did not in an undergraduate college population sample at a large public university in the Southeast. The sample consisted of 429 undergraduate students who completed online measures of demographics, perceived stress, stressful life events, and substance use. Overall, 3.4% of the sample reported …

The Effects Of The Transition From Pre-Nursing To Nursing On Mental Health, Andrew J. Davis, Paige R. Mullins, Kimberly A. Sell

Undergraduate Honors Theses

Mental health is an ever-growing crisis among adolescents and young adults, with suicide as second leading cause of death and the number of those negatively affected continually on the rise. Transitions are one of the major stressors prevalent among these age groups, placing individuals at risk for mental health deficits. This quantitative voluntary response comparative study assesses the transitional mental health of pre-nursing students and students in the nursing program at East Tennessee State University. Emailed to all with a declared major of pre-nursing or nursing, this study measured mental health using evidenced based assessment tools. The PHQ-9 for depression …

The Moderating Role Of Social Support In Stigma And Symptoms Of Anxiety And Depression, Taylor Phillips

Undergraduate Honors Theses

In this study, we examine the relationship between having a support system and the stigma individuals face with depression and anxiety symptoms. The aim of this study was to examine if having a support system acts as a buffer between perceived stigma and mental health symptoms. For this study, I conducted an online survey to measure symptoms of depression and anxiety, experiences with both perceived and internalized stigma, and social support. While 93 total participants engaged in the survey, only 52 fully completed the survey and passed two attention-check questions to ensure no invalid participation (e.g., BOTS) were present. In …

Effect Of A Self-Care And Self-Awareness Education Program On Resilience To Burnout And Depression In Clinically Experienced Nursing Students, Andrew Taylor

Undergraduate Honors Theses

The purpose was to examine the effect of a self-care educational intervention on nursing student resilience and thus the potential for compassion fatigue, depersonalization, burnout, depression, and inadequate self-care. A one-group pretest-posttest research design was applied to a convenience sample of 104 nursing students near the end of their last semester in a baccalaureate nursing program. The measurements were demographics, a psychometric resilience scale, program evaluation, and reflection question. The intervention was a standardized, intensive 30 min training program on the high degree of stress and burnout nurses face and the core self-care methods that can promote resilience to these …

The Effects Of An Adenosine A(2a) Agonist As An Adjunctive Treatment To Alleviate Sensorimotor Gating Deficits In A Rodent Model Of Schizophrenia, Hannah Rauhuff

Undergraduate Honors Theses

The adenosine system has become a promising target for the treatment of schizophrenia due to its unique relationship with dopamine D₂ receptors. Dopamine D₂ receptors display heightened sensitivity in schizophrenia, and inhibition of these receptors has been shown to alleviate some of the psychotic symptoms of the disorder. Inhibition of adenosine A(2A) receptors has been shown to decrease dopamine D₂ receptor sensitivity, making this receptor a potential target for treatment of the disorder. This effect occurs because adenosine A(2A) receptors form a mutually inhibitory heterodimeric complex with dopamine D₂ receptors. The present study looked at the …

Use Of Music To Reduce Anxiety In Short Wait Periods For Patients Receiving Care In An Urgent Care Clinic, Rebecca Anne Parker

Undergraduate Honors Theses

Abstract

The concept of waiting has received limited attention in the world of research. In modern society, waiting has become a commonplace event, especially in healthcare. Although the waiting experience can produce anxiety, healthcare environments can be easily manipulated in order to increase human comfort and reduce situational anxiety. One such way of accomplishing this is to introduce music to an environment. This paper will discuss the findings related to short wait periods, anxiety, and music within the literature, and the findings within this research study. This study found listener-selected music to be statistically effective in reducing anxiety for patients …

Executive Function Predictors Of Children's Talk, Jacqlyne D. Weber

Undergraduate Honors Theses

Relatively few studies have investigated the relationship between executive functioning (EF) and language development, and even fewer have researched hot and cool EF as a predictor language development. This study is an investigation into the relationship between EF and language development in preschool aged children. More specifically, the ability for hot or cool EF to predict language, this will be the focus of the study. It was found that hot EF was a better predictor of language development in preschool aged children.

Perceived Barriers To Obtaining Psychiatric Treatment At Johnson City Community Health Center, Mychal Bolton

Undergraduate Honors Theses

The purpose of this study was to describe the perceived barriers to obtaining psychiatric treatment at the Johnson City Community Health Center. The context of the study was a rural area in Eastern Tennessee. Five patients with confirmed DSM-IV mental health diagnoses were recruited during treatment and interviewed at the Johnson City Community Health Center after their scheduled appointments with a Mental Health Nurse Practitioner (MHNP). The semi-structured interview focused on perceived barriers to obtaining treatment, perceptions of treatment received, and perceived availability of treatment. From those interviews, two themes were identified and each of which had two sub-themes identified: …

Comparison Between Two Methodological Paradigms Of Conditioned Place Preference With Methlyphenidate., Bryce D. Watson

Undergraduate Honors Theses

The aim of this thesis is to examine the mechanisms of Methylphenidate (MPH) on Conditioned Place Preference (CPP), a behavioral test of reward. The psychostimulant MPH is therapeutically used in the treatment of ADHD, but has been implicated in many pharmacological actions related to drug addiction and is considered to have abuse potential. Past work in our lab and others have shown substantial sex-differences in the neuropharmacological profile of MPH. Here a discussion of the relevant mechanisms of action of MPH and its relationship to neurotrophins and CPP are reviewed. Furthermore, previous work is reviewed and a rationale for two …

Random Inter Stimulus Interval Increases Signal-To-Noise Ratio., Juliane Armstrong

Undergraduate Honors Theses

Incremental improvements are continuously being made to P300-Speller BCI paradigms. Accurate classification depends on a high signal-to-noise ratio (SNR) between the target and nontarget items. Fixed presentation rates produce a large flash-evoked response that persists throughout the recording epoch, which can potentially undermine the classification of P300-responses. By introducing a random interstimulus interval (ISI) to a previously improved P300-Speller paradigm (i.e., Checkerboard Paradigm; CBP) we expect to reduce the deleterious flash-evoked responses and increase the P300 classification SNR. Data were recorded from 32 EEG locations (right mastoid referenced) from 13 subjects using the CBP with two conditions. In the Random …

Nicotine Sensitization And Brain-Derived Neurotrophic Factor Content In Adolescent Rats Neonatally Treated With Quinpirole., Addie Roberts

Undergraduate Honors Theses

Neonatal treatment of quinpirole in rats increases dopamine D2-like receptor sensitivity over the animal’s lifetime, a phenomenon referred to as D2 priming. Male and female Sprague-Dawley rats were given quinpirole (1mg/kg, i.p.) or saline on postnatal days (P)1-21. After habituation to a locomotor arena on P29-31, beginning P33, animals were administered nicotine (0.3 mg/kg, 0.5 mg/kg, or 0.7 mg/kg, i.p.) or saline and placed into a locomotor arena for behavioral testing every second day for a total of 9 treatments. The results showed that adolescents neonatally treated with quinpirole produced more enhanced sensitization to nicotine than controls. Brains tissues were …

Brain-Derived Neurotrophic Factor Levels In D2 Receptor Primed Adolescent Rats Given Twice Daily Nicotine Administrations., Josie Minnigh

Undergraduate Honors Theses

Nicotine use is very prevalent in the schizophrenic population, which is a 2.5 fold greater than the general population. In the present study, the drug quinpirole (dopamine D2/D3 agonist) or saline was given neonatally to 25 Sprague-Dawley male and female rats. Rats were randomly assigned to condition. Beginning postnatal day 33 animals were given twice daily administrations of nicotine (0.5 mg/kg free base). After the first of the daily injections they were placed in a locomotor arena every other day for behavioral testing. One day after behavioral testing, the dorsal striatum and nucleus accumbens were removed for brain-derived neurotrophic factor …