Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Medicine and Health Sciences
Let’S Have A Playdate! Comparing Autistic Children's Social Behavior During Play Sessions With Siblings Versus Peers, Clare Boldt
Let’S Have A Playdate! Comparing Autistic Children's Social Behavior During Play Sessions With Siblings Versus Peers, Clare Boldt
Scripps Senior Theses
Autistic individuals can struggle with social interactions and forming friendships. While siblings and peers are used for social skills intervention, there is a paucity of research analyzing differences in autistic children’s play with siblings versus peers. Investigating these behavior differences helps clinicians learn how to best support social skill development, improve sibling relationships, and determine ideal peer mediators for interventions. I compare social behaviors of autistic children during play sessions with their sibling versus a non-sibling peer. The behaviors measured were prosocial behaviors, cooperative and parallel play, verbalizations (appropriate and inappropriate), aggressive behaviors, eloping, and stereotypy. Based on previous literature, …
Putative Mechanisms Underlying The Antidepressant Actions Of Ketamine: A Review And Study Proposal, Tristan Reece
Putative Mechanisms Underlying The Antidepressant Actions Of Ketamine: A Review And Study Proposal, Tristan Reece
CMC Senior Theses
Major Depressive Disorder (MDD) is a highly debilitating and common psychiatric disorder that affects over 250 million people globally; it is among the most financially and emotionally burdensome illnesses in the world. Currently approved antidepressants are suboptimal in their efficacy and latency of therapeutic action. In contrast, single administrations of sub-anesthetic ketamine have been shown to rapidly alleviate depressive symptoms within hours, even in treatment-resistant patients. Ketamine is believed to exert these effects by increasing glutamatemediated neurotransmission and promoting rapid neurotrophic factor release, restoring the integrity of neural circuits that are compromised in depression. However, uncertainty surrounding its specific antidepressant …