Medicine and Health Sciences Commons^™

Neck Muscle Composition In Persistent Whiplash Associated Disorder: A Relationship With Disability, Bradford G. Callan

Department of Physical Therapy Student Theses, Dissertations and Capstones

Purpose/hypothesis: Neck pain and related symptoms following a motor vehicle collision (MVC) can significantly influence the quality of life for some people. While the MVC related mechanics of the head and neck gives rise to the term whiplash, the signs and symptoms of neck related disability are often complex and are clinically referred to as whiplash associated disorder(WAD). Muscle fatty infiltrate (MFI) has been associated with persistent WAD, but its influence on the generation and maintenance of WAD is largely unknown. The purpose of this study was to evaluate the relationship between MFI and baseline demographic variables related to persistent …

Psychosocial Predictors Of Chronic Pain And Pain-Related Disability 12 Months After Lower Extremity Fracture, Joshua Judson Van Wyngaarden

Theses and Dissertations--Rehabilitation Sciences

Over 700,000 lower extremity fractures occur each year with a large portion of these patients developing adverse long-term pain and disability outcomes. Current literature indicates that 39% to 62.7% of all patients report continued pain long after traumatic lower extremity fracture. Concurrent physical limitations and reduced quality of life are common, with nearly one-third of all patients reporting pain-related disability seven years after limb threatening trauma, and approximately 50% of these patients having limitations in functional mobility and activities of daily living at long-term follow-up. These poor long-term injury-related pain and disability outcomes are alarming and require further action to …

The Resolve Trial For People With Chronic Low Back Pain: Statistical Analysis Plan, Matthew K. Bagg, Serigne Lo, Aidan G. Cashin, Robert D. Herbert, Neil E. O'Connell, Hopin Lee, Markus Hubscher, Benedict M. Wand, Edel O'Hagan, Rodrigo R.N Rizzoli, G Lorimer Moseley, Tasha R. Stanton, Christopher G. Maher, Stephen Goodall, Sopany Saing, James H. Mcauley

Physiotherapy Papers and Journal Articles

Background: Statistical analysis plans describe the planned data management and analysis for clinical trials. This supports transparent reporting and interpretation of clinical trial results. This paper reports the statistical analysis plan for the RESOLVE clinical trial. The RESOLVE trial assigned participants with chronic low back pain to graded sensory-motor precision training or sham-control.

Results: We report the planned data management and analysis for the primary and secondary outcomes. The primary outcome is pain intensity at 18-weeks post randomization. We will use mixed-effects models to analyze the primary and secondary outcomes by intention-to-treat. We will report adverse effects in full. We …