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Physical Therapy

Philadelphia College of Osteopathic Medicine

Theses/Dissertations

Acute lymphoblastic leukemia

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Full-Text Articles in Medicine and Health Sciences

Does The Use Of Blinatumomab Improve The Overall Survival Rate In Adults With Relapsed/Refractory Acute Lymphoblastic Leukemia?, Julia Colangeli Jan 2022

Does The Use Of Blinatumomab Improve The Overall Survival Rate In Adults With Relapsed/Refractory Acute Lymphoblastic Leukemia?, Julia Colangeli

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review paper is to determine whether or not, “Does the use of blinatumomab improve the overall survival rate in adults with relapsed/refractory acute lymphoblastic leukemia?”

Study Design: A systematic review of two RCTs and one case-based series were utilized. All studies were published between 2014-2019.

Data Sources: The two RCTs were found through PubMed and the case-based series was obtained through CINAHL Plus. All the studies were published in peer-reviewed journals.

Outcomes Measured: The main outcome measured in all the studies was overall survival. Both RCTs defined overall survival as the time from …