Medicine and Health Sciences Commons^™

Heightened Levels Of Stress And Contributing Factors In Caregivers Of Special Needs Children, Heather Velon

Georgia State Undergraduate Research Conference

No abstract provided.

Addition Of Hip Exercises To Treatment Of Patellofemoral Pain Syndrome: A Meta-Analysis, Kimberly Morelli, Maria Carrelli, Maria Nunez, Carolina A. Smith, Gordon L. Warren

Physical Therapy Faculty Publications

AIM: To determine if the addition of hip-strengthening exercises decreases pain and improves function in patients with patellofemoral pain syndrome.

METHODS: The authors completed a systematic review searching eight databases (i.e. , PubMed, Cochrane, CINHAL, MEDLINE, SportsDiscus, EMBASE, APTA Hooked on Evidence, and PEDro). Two independent reviewers screened and excluded studies if they did not meet the following inclusion criteria: subjects had a primary diagnosis of patellofemoral pain syndrome (PFPS), intervention group included hip-strengthening exercises, control group included a traditional physical therapy intervention, study included outcome measures of pain and/or function, study used a randomized controlled trial design, PEDro score …

Functional Organization And Restoration Of The Brain Motor-Execution Network After Stroke And Rehabilitation, Sahil Bajaj, Andrew Butler, Daniel Drake, Mukesh Dhamala

Physics and Astronomy Faculty Publications

Multiple cortical areas of the human brain motor system interact coherently in the low frequency range (<0.1 Hz), even in the absence of explicit tasks. Following stroke, cortical interactions are functionally disturbed. How these interactions are affected and how the functional organization is regained from rehabilitative treatments as people begin to recover motor behaviors has not been systematically studied. We recorded the intrinsic functional magnetic resonance imaging (fMRI) signals from 30 participants: 17 young healthy controls and 13 aged stroke survivors. Stroke participants underwent mental practice (MP) or both mental practice and physical therapy (MP+PT) within 14–51 days following stroke. We investigated the network activity of five core areas in the motor-execution network, consisting of the left primary motor area (LM1), the right primary motor area (RM1), the left pre-motor cortex (LPMC), the right pre-motor cortex (RPMC) and the supplementary motor area (SMA). We discovered that (i) the network activity dominated in the frequency range 0.06–0.08 Hz for all the regions, and for both able-bodied and stroke participants (ii) the causal information flow between the regions: LM1 and SMA, RPMC and SMA, RPMC and LM1, SMA and RM1, SMA and LPMC, was reduced significantly for stroke survivors (iii) the flow did not increase significantly after MP alone and (iv) the flow among the regions during MP+PT increased significantly. We also found that sensation and motor scores were significantly higher and correlated with directed functional connectivity measures when the stroke-survivors underwent MP+PT but not MP alone. The findings provide evidence that a combination of mental practice and physical therapy can be an effective means of treatment for stroke survivors to recover or regain the strength of motor behaviors, and that the spectra of causal information flow can be used as a reliable biomarker for evaluating rehabilitation in stroke survivors.

Randomized, Placebo-Controlled, Double-Blind Pilot Study Of D-Cycloserine In Chronic Stroke, Andrew Butler, Justiss Kallos, Stephen N. Housley, Michelle Laplaca, Stephen F. Traynelis, Stephen L. Wolf

Physical Therapy Faculty Publications

Stroke is a leading cause of death and disability in the USA. Up to 60% of patients do not fully recover despite intensive physical therapy treatment.N-Methyl-D-aspartate receptors(NMDA-R) have been shown to play a role in synaptic plasticitywhen activated. D-Cycloserine promotes NMDA receptor function by binding to receptors with unoccupied glycine sites. These receptors are involved in learning and memory.We hypothesized thatD-cycloserine,when combined with robotic-assisted physiotherapy (RAP), would result in greater gains compared with placebo + RAP in stroke survivors. Participants (𝑛 = 14) were randomized to Dcycloserine plus RAP or placebo plus RAP. Functional, cognitive, and quality-of-life measures were used …

Randomized, Placebo-Controlled, Double-Blind Pilot Study Of D-Cycloserine In Chronic Stroke, Andrew Butler, Justiss Kallos, Stephen N. Housley, Michelle Laplaca, Stephen F. Traynelis, Stephen L. Wolf

Physical Therapy Faculty Publications

Stroke is a leading cause of death and disability in the USA. Up to 60% of patients do not fully recover despite intensive physical therapy treatment. N-Methyl-D-aspartate receptors (NMDA-R) have been shown to play a role in synaptic plasticity when activated. D-Cycloserine promotes NMDA receptor function by binding to receptors with unoccupied glycine sites. These receptors are involved in learning and memory. We hypothesized that D-cycloserine, when combined with robotic-assisted physiotherapy (RAP), would result in greater gains compared with placebo + RAP in stroke survivors. Participants (n=14) were randomized to D-cycloserine plus RAP or placebo plus RAP. Functional, …

Effect Of A Home-Based Virtual Reality Intervention For Children With Cerebral Palsy Using Super Pop Vr Evaluation Metrics: A Feasibility Study, Yuping Chen, Sergio Garcia-Vergara, Ayanna M. Howard

Physical Therapy Faculty Publications

Objective. The purpose of this pilot study was to determine whether Super Pop VR, a low-cost virtual reality (VR) system, was a feasible system for documenting improvement in children with cerebral palsy (CP) and whether a home-based VR intervention was effective. Methods. Three children with CP participated in this study and received an 8-week VR intervention (30 minutes × 5 sessions/week) using the commercial EyeToy Play VR system. Reaching kinematics measured by Super Pop VR and two fine motor tools (Bruininks-Oseretsky Test of Motor Proficiency second edition, BOT-2, and Pediatric Motor Activity Log, PMAL) were tested before, mid, and after …