Medicine and Health Sciences Commons^™

Determination Of The N-Terminal Amino Acid Residues On Polypeptides In Secondary Wastewaters, Edward L. Creecy

Chemistry & Biochemistry Theses & Dissertations

The N-terminal amino acid residues on polypeptides and proteins were determined in wastewaters prior to chlorination. The terminal amino groups'ere first derivatized with the well known derivatizing agent dansyl chloride, and then the resulting dansyl amino acid hydrolyzed from the peptide chain by a propionic acid/ hydrochloric acid mixture. The resulting dansyl amino acids were then separated and detected using reversed phase high performance liquid chromatography with fluorescence detection. The majority of N-terminal residues detected were the more polar amino acids. Concentrations ranged from 1 x 10^-10 to 3 x 10^-7 moles/liter. It is suggested that the shorter …

Analyzing The Effects Of Display Characteristics And Cognitive Variables On Performance Using Keystroke And Eye Movement Data, Orhan E. Beckman

Psychology Theses & Dissertations

Information about how operators use their eyes while interacting with visual displays is often an overlooked aspect of human-computer interaction. Such information is fundamental to assessing the quality of software interfaces and understanding the cognitive processes that underlie operator behavior. Other research evaluating information displays evolved from using reaction time and subjective data as dependent variables to using oculometric measures. In the current research conventional performance measures are coupled with oculometric measures to evaluate the influence display characteristics and cognitive variables have on performance.

Twelve subjects used a software program to complete a series of specified tasks. Subjects were asked …

Reaction-Diffusion Models Of Cancer Dispersion, Kim Yvette Ward

Mathematics & Statistics Theses & Dissertations

The phenomenological modeling of the spatial distribution and temporal evolution of one-dimensional models of cancer dispersion are studied. The models discussed pertain primarily to the transition of a tumor from an initial neoplasm to the dormant avascular state, i.e. just prior to the vascular state, whenever that may occur. Initiating the study is the mathematical analysis of a reaction-diffusion model describing the interaction between cancer cells, normal cells and growth inhibitor. The model leads to several predictions, some of which are supported by experimental data and clinical observations $\lbrack25\rbrack$. We will examine the effects of additional terms on these characteristics. …

Mathematical Models Of Tumors And Their Remote Metastases, Carryn Bellomo

Mathematics & Statistics Theses & Dissertations

Clinical observations and indications in the literature have led us to investigate several models of tumors. For example, it has been shown that a tumor has the ability to send out anti-growth factors, or inhibitors, to keep its remote metastases from growing. Thus, we model the depleting effect of such a growth inhibitor after the removal of the primary tumor (thus removing the source) as a function of time t and distance from the original tumor r.

It has also been shown clinically that oxygen and glucose are nutrients critical to the survival and growth of tumors. Thus, we model …