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2022

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Articles 1 - 30 of 116

Full-Text Articles in Medicine and Health Sciences

Designing And Synthesizing A Warhead-Fragment Inhibitory Ligand For Ivyp1 Through Fragment-Based Drug Discovery, Samuel Moore Dec 2022

Designing And Synthesizing A Warhead-Fragment Inhibitory Ligand For Ivyp1 Through Fragment-Based Drug Discovery, Samuel Moore

Symposium of Student Scholars

Fragment-based drug discovery (FBDD) is a powerful tool for developing anticancer and antimicrobial agents. Within this, magnetic resonance spectroscopy (NMR) provides a comprehensive qualitative and quantitative approach to screening and validating weak and robust binders with targeted proteins, making NMR among the most attractive strategies in FBDD. Inhibitor of vertebrate lysozyme (Ivyp1) of P. aeruginosa serves as an excellent target because of its active cellular location and implications in clinical prognosis for cystic fibrosis and immunocompromised patients. This study uses current NMR and biophysical techniques to develop a covalent, fragment-linked warhead inhibitor for Ivyp1 through synthetic methods, warhead linking, and …


A Framework For Securing Edge Computing In Medical Devices, David Mcquaid Nov 2022

A Framework For Securing Edge Computing In Medical Devices, David Mcquaid

HECA Research Conference

Edge computing brings data collection, processing and analysis closer to data sources, either enabling execution within devices themselves or outsourcing to local servers and data centres instead of central locations The basic idea is to minimize data transmission time as much as possible and to leverage the implicit processing power that most IOT’s hardware possess.


Physics-Informed Neural Networks For Informed Vaccine Distribution In Heterogeneously Mixed Populations, Alvan Arulandu, Padmanabhan Seshaiyer Nov 2022

Physics-Informed Neural Networks For Informed Vaccine Distribution In Heterogeneously Mixed Populations, Alvan Arulandu, Padmanabhan Seshaiyer

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Humanizing Mathematical Biology Research And Education, Carrie Diaz Eaton, Ognyan Simeonov Nov 2022

Humanizing Mathematical Biology Research And Education, Carrie Diaz Eaton, Ognyan Simeonov

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


The Effect Of Vaccine Misinformation On Disease Spread, Anthony Delegge, Yina Wang Nov 2022

The Effect Of Vaccine Misinformation On Disease Spread, Anthony Delegge, Yina Wang

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Stochastic Models Of Zoonotic Avian Influenza With Multiple Hosts, Environmental Transmission, And Migration In The Natural Reservoir, Kaia Smith Nov 2022

Stochastic Models Of Zoonotic Avian Influenza With Multiple Hosts, Environmental Transmission, And Migration In The Natural Reservoir, Kaia Smith

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Modeling The Effects Of Media Awareness On Sars-Cov-2 Transmission In Georgia, Eric Numfor Nov 2022

Modeling The Effects Of Media Awareness On Sars-Cov-2 Transmission In Georgia, Eric Numfor

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


An Agent-Based Model Of Covid-19 Transmission At Lewis University, Austin Kind, Brittany Stephenson Phd Nov 2022

An Agent-Based Model Of Covid-19 Transmission At Lewis University, Austin Kind, Brittany Stephenson Phd

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


Ischaemic Hepatitis (Ih): Modeling Outcome Based On Ih Patients' Attributes, Madison Utterback, Christiana Beard Nov 2022

Ischaemic Hepatitis (Ih): Modeling Outcome Based On Ih Patients' Attributes, Madison Utterback, Christiana Beard

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.


11th International Conference On Business, Technology And Innovation 2022, University For Business And Technology - Ubt Oct 2022

11th International Conference On Business, Technology And Innovation 2022, University For Business And Technology - Ubt

UBT International Conference

Welcome to IC – UBT 2022

UBT Annual International Conference is the 11th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make …


Rheological Characterization Of Blood-Mimicking Fluids For Use In Particle Image Velocimetry, Anorin S. Ali Aug 2022

Rheological Characterization Of Blood-Mimicking Fluids For Use In Particle Image Velocimetry, Anorin S. Ali

Undergraduate Student Research Internships Conference

Blood-mimicking fluids (BMFs) are often used to investigate blood flow using physical replicas of vessels with cardiovascular disease. Particle image velocimetry (PIV) is used with silicone poly-dimethyl siloxane (PDMS) vascular models to visualize this flow. The challenge is creating a blood-mimicking fluid that matches the viscosity profile, viscoelasticity, and density of whole blood while also matching the refractive index (RI) of PDMS. Water-glycerol solutions are commonly used with sodium iodide (NaI) added to increase the RI without changing viscosity. However, NaI is expensive, stains easily, and turns fluids from optically clear to yellow in less than a day. Furthermore, without …


Reporting Standards For Machine Learning Research In Type 2 Diabetes, Grace Kang Aug 2022

Reporting Standards For Machine Learning Research In Type 2 Diabetes, Grace Kang

Undergraduate Student Research Internships Conference

In this project, three people scored 90 papers on machine learning predictive models for type 2 diabetes to assess their adherence to TRIPOD, MI-CLAIM, and DOME reporting guidelines.


Producing And Measuring Oscillatory Shear In A Novel Microfluidic Chip, Sanaz Lordfard, Daniel Lorusso, Tamie L. Poepping, Hristo N Nikolov, Kayla Soon, Stephen Sims, Jeffrey Dixon, David Holdsworth Aug 2022

Producing And Measuring Oscillatory Shear In A Novel Microfluidic Chip, Sanaz Lordfard, Daniel Lorusso, Tamie L. Poepping, Hristo N Nikolov, Kayla Soon, Stephen Sims, Jeffrey Dixon, David Holdsworth

Undergraduate Student Research Internships Conference

Purpose: To demonstrate the effectiveness of a novel microfluidic device mimicking oscillatory blood flow, allowing cell biologists to examine how endothelial cells respond to a range of oscillatory shear stress levels.

Methods: The microfluidic chip consists of a circular-shaped reservoir, leading to a rectangular channel that is examined under a microscope. The plunger is connected to a speaker system and oscilloscope, allowing the plunger to apply a range of frequencies (5-60Hz) and voltages (5-10 V, leading to a variety in oscillation amplitudes) to the reservoir region. 1.1 um fluorescent particles diluted in distilled water were used for tracking. Processing was …


Boxed Lunches, Lunch May 2022

Boxed Lunches, Lunch

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mathematics Of A Single-Locus Model For Assessing The Impacts Of Pyrethroid Resistance And Temperature On Population Abundance Of Malaria Mosquitoes, Jemal Mohammed-Awel May 2022

Mathematics Of A Single-Locus Model For Assessing The Impacts Of Pyrethroid Resistance And Temperature On Population Abundance Of Malaria Mosquitoes, Jemal Mohammed-Awel

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mathematical Model Of Subthalamic Nucleus Neuron - Characteristic Activity Patterns And Bifurcation Analysis, Choongseok Park, Sungwoo Ahn, Leonid Rubchinsky May 2022

Mathematical Model Of Subthalamic Nucleus Neuron - Characteristic Activity Patterns And Bifurcation Analysis, Choongseok Park, Sungwoo Ahn, Leonid Rubchinsky

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling The Dynamics Of Usutu Virus Infection In Birds, Nora G. Heitzman-Breen May 2022

Modeling The Dynamics Of Usutu Virus Infection In Birds, Nora G. Heitzman-Breen

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Acute And Chronic Vascular Adaptations To A Major Arterial Occlusion, Erin O. Zhao May 2022

Modeling Acute And Chronic Vascular Adaptations To A Major Arterial Occlusion, Erin O. Zhao

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mechanical Parameters Fitting For Layer-Reduced Umbilical Arteries Used For Grafting, Kun Gou May 2022

Mechanical Parameters Fitting For Layer-Reduced Umbilical Arteries Used For Grafting, Kun Gou

Biology and Medicine Through Mathematics Conference

No abstract provided.


Epidemiological Assessment Of Wolbachia-Based Biocontrol For Reduction Of Dengue Morbidity, Olga Vasilieva, Oscar E. Escobar, Hector J. Martinez, Pierre-Alexandre Bliman, Yves Dumont May 2022

Epidemiological Assessment Of Wolbachia-Based Biocontrol For Reduction Of Dengue Morbidity, Olga Vasilieva, Oscar E. Escobar, Hector J. Martinez, Pierre-Alexandre Bliman, Yves Dumont

Biology and Medicine Through Mathematics Conference

No abstract provided.


Model Of Quarantine Implementation In An Animal Shelter For Canine Distemper Outbreak, Virginia Parkman, Nick Cogan May 2022

Model Of Quarantine Implementation In An Animal Shelter For Canine Distemper Outbreak, Virginia Parkman, Nick Cogan

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mathematical Model Of Triple-Negative Breast Cancer In Response To Combination Chemotherapies, Angelica Davenport, Yun Lu, Carlos Gallegos, Adriana Massicano, Katherine Heinzman, Patrick Song, Anna Sorace, Nick Cogan May 2022

Mathematical Model Of Triple-Negative Breast Cancer In Response To Combination Chemotherapies, Angelica Davenport, Yun Lu, Carlos Gallegos, Adriana Massicano, Katherine Heinzman, Patrick Song, Anna Sorace, Nick Cogan

Biology and Medicine Through Mathematics Conference

No abstract provided.


Coffee Break, Coffee Break May 2022

Coffee Break, Coffee Break

Biology and Medicine Through Mathematics Conference

No abstract provided.


Plenary: Cardiovascular Models In Vascular Disease, Mette Olufsen May 2022

Plenary: Cardiovascular Models In Vascular Disease, Mette Olufsen

Biology and Medicine Through Mathematics Conference

No abstract provided.


Using A Network Model To Control The Spread Of An Infectious Disease On A College Campus With Contact Tracing, Christopher R. Boyette May 2022

Using A Network Model To Control The Spread Of An Infectious Disease On A College Campus With Contact Tracing, Christopher R. Boyette

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Mathematical Model For Biological Field Effect Tranistors, Ryan M. Evans, Seulki Cho, Arvind Ballijepalli, Anthony Kearsley May 2022

A Mathematical Model For Biological Field Effect Tranistors, Ryan M. Evans, Seulki Cho, Arvind Ballijepalli, Anthony Kearsley

Biology and Medicine Through Mathematics Conference

No abstract provided.


Understanding Biofilm-Phage Interactions In Mathematical Framework, Blessing Emerenini May 2022

Understanding Biofilm-Phage Interactions In Mathematical Framework, Blessing Emerenini

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Mathematical Model Of Microtubule Assembly And Polarity In Dendrites, Anna Nelson May 2022

A Mathematical Model Of Microtubule Assembly And Polarity In Dendrites, Anna Nelson

Biology and Medicine Through Mathematics Conference

No abstract provided.


Optimal Intervention Strategies To Minimize Spread Of Infectious Diseases And Economic Impact On A Dynamic Small-World Network, Malindi Whyte, Danielle Dasilva May 2022

Optimal Intervention Strategies To Minimize Spread Of Infectious Diseases And Economic Impact On A Dynamic Small-World Network, Malindi Whyte, Danielle Dasilva

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling The Effects Of Media Coverage On The Covid-19 Transmission Dynamics., Ana L. Vivas-Barber, Anne Fernando Phd, Evelyn Thomas Phd May 2022

Modeling The Effects Of Media Coverage On The Covid-19 Transmission Dynamics., Ana L. Vivas-Barber, Anne Fernando Phd, Evelyn Thomas Phd

Biology and Medicine Through Mathematics Conference

No abstract provided.