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Full-Text Articles in Medicine and Health Sciences
Operations Research Methods For Optimization In Radiation Oncology, M Ehrgott, Allen Holder
Operations Research Methods For Optimization In Radiation Oncology, M Ehrgott, Allen Holder
Mathematical Sciences Technical Reports (MSTR)
Operations Research has a successful tradition of applying mathematical analysis to a wide range of applications, with one of the burgeoning areas of growth being in medical physics. The original application was in the optimal design of the influence map for a radiotherapy treatment, a problem that has continued to receive attention. However, operations research has been applied to other clinical problems like patient scheduling, vault design, and image alignment. The overriding theme of this article is to present how techniques in operations research apply to clinical problems, which we accomplish in three parts. First, we present the perspective from …
A Clustering Approach For Optimizing Beam Angles In Imrt Planning, Gino J. Lim, Allen Holder, Josh Reese
A Clustering Approach For Optimizing Beam Angles In Imrt Planning, Gino J. Lim, Allen Holder, Josh Reese
Mathematical Sciences Technical Reports (MSTR)
In this paper we introduce a p-median problem based clustering heuristic for selecting efficient beam angles for intensity-modulated radiation therapy. The essence of the method described here is the clustering of beam angles according to probability that an angle will be observed in the final solution and similarities among different angles and the selection of a representative angle from each of the p resulting cluster cells. We conduct experiments using several combinations of modeling parameters to find the conditions where the heuristic best performs. We found a combination of such parameters that outperformed all other parameters on three of the …