Medicine and Health Sciences Commons^™

Environmental Communication: Changing The Attitude-Behavioral Gap In Science Communication Utilizing Strategic Messaging, Carrie Helgeson Nelms

Graduate Theses and Dissertations

National Polls in the United States consistently find the public’s beliefs and attitudes about climate change and other environmental issues significantly diverge from those held by the science community. A communication gap between the findings on the causes and effects of environmental issues and the public’s inability to interpret or refuse to accept these findings are possible causes of this divergence. This communication gap constitutes a threat to society because of inaction to environmental problems and points to needed changes in scientific messaging that better informs and motivates behavioral change. The present research employed a strategic message design to affect …

The Effects Of Metronomic And Maximum-Tolerated Dose Chemotherapy In Colorectal Cancer Angiogenesis: A Combined Approach Using Endoscopic Diffuse Reflectance Spectroscopy And Mrna Expression, Ariel Isaac Mundo Ortiz

Graduate Theses and Dissertations

Colorectal cancer (CRC) continues to be one of the most incident and deadliest types of cancer worldwide. Chemotherapy has proven effective to reduce tumor burden for CRC patients, but there are several disadvantages associated with the use of mainstay maximtolerated dose (MTD) chemotherapeutic strategies. Metronomic chemotherapy (MET) has been developed as an alternative that addresses the shortcomings of maximum-tolerated dose chemotherapy but so far its effectiveness as a neoadjuvant strategy for CRC has not been explored.

This dissertation uses a combined optics and molecular biology approach (using diffuse reflectance spectroscopy and mRNA expression) to study the changes in angiogenesis and …