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Developing A Presumptive Test For Select Synthetic Cannabinoids, Carrie Snyder Dec 2013

Developing A Presumptive Test For Select Synthetic Cannabinoids, Carrie Snyder

Graduate Theses and Dissertations

Synthetic cannabinoids (SC's) began to gain popularity around the world in 2009. Since then, many of the compounds have been outlawed and methods developed to detect them and their metabolites using mass spectrometry. Our work investigated the possibility of developing a colorimetric presumptive test. The SC JWH-019 was synthesized and its ketone targeted as a possible reaction site. Many SC's contain ketones and thus a reaction at this site would be applicable to many of the compounds. Since JWH-019 is costly and time consuming to synthesize, much of the experimental work was done using benzophenone (BP). BP contains a diaryl …


Consumer Adoption Of Health Information Systems, Sankara Subramanian Srinivasan Dec 2013

Consumer Adoption Of Health Information Systems, Sankara Subramanian Srinivasan

Graduate Theses and Dissertations

At nearly 18 percent of the country's GDP, the U.S. healthcare industry continues to wrestle with growing cost and a quality of care that does not match the increased spending. The dominant focus to date has been on promoting Health IT (HIT) system implementation and digitizing health records at the provider's end, with scant attention to the role of the patient in the healthcare process. The source of inefficiency in the healthcare system is not only on account of shortcomings at the provider's end but also due to non-compliance (such as failing to adhere to medication advice and follow-up visits) …


Design And Fabrication Of Nanofluidic Systems With Integrated Sensing Electrodes For Rapid Biomolecule Characterization, Taylor Bradley Busch May 2013

Design And Fabrication Of Nanofluidic Systems With Integrated Sensing Electrodes For Rapid Biomolecule Characterization, Taylor Bradley Busch

Graduate Theses and Dissertations

A transparent nanofluidic system with embedded sensing electrodes was designed and fabricated by integrating Atomic Force Microscopy (AFM) nanolithography, Focused Ion Beam (FIB) milling and metal deposition, and standard microfabrication processing. The fabrication process started with the evaporation of chrome/gold (Cr/Au) onto a Pyrex 7740 wafer followed by photolithography and wet etching of the microchannels. The wafer was patterned a second time to form Au microelectrodes with 15-45 micrometer separation gaps in the nanochannel region. Sensing electrodes (up to one micron wide) were then deposited using FIB to bridge the gaps. The nanochannels were realized through both AFM nanolithography and …