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Full-Text Articles in Medicine and Health Sciences
Childhood Body Mass Index Trajectories: Modeling, Characterizing, Pairwise Correlations And Socio-Demographic Predictors Of Trajectory Characteristics, Xiaozhong Wen, Ken Kleinman, Matthew W. Gillman, Sherly L. Rifas-Shiman, Elsie M. Taveras
Childhood Body Mass Index Trajectories: Modeling, Characterizing, Pairwise Correlations And Socio-Demographic Predictors Of Trajectory Characteristics, Xiaozhong Wen, Ken Kleinman, Matthew W. Gillman, Sherly L. Rifas-Shiman, Elsie M. Taveras
Public Health Department Faculty Publication Series
BACKGROUND:
Modeling childhood body mass index (BMI) trajectories, versus estimating change in BMI between specific ages, may improve prediction of later body-size-related outcomes. Prior studies of BMI trajectories are limited by restricted age periods and insufficient use of trajectory information.
METHODS:
Among 3,289 children seen at 81,550 pediatric well-child visits from infancy to 18 years between 1980 and 2008, we fit individual BMI trajectories using mixed effect models with fractional polynomial functions. From each child's fitted trajectory, we estimated age and BMI at infancy peak and adiposity rebound, and velocity and area under curve between 1 week, infancy peak, adiposity …
Estimation Of Newborn Risk For Child Or Adolescent Obesity:Lessons From Longitudinal Birth Cohorts, Anita Morandi, David Meyre, Stephane Lobbens, Ken Kleinman, Marika Kaakinen, Sheryl L. Rifas-Shiman, Vincent Vatin, Stefan Gaget, Anneli Pouta, Anna-Liisa Hartikainen, Jaana Laitinen, Matthew W. Gillman, Marjo-Riitta Jarvelin, Philippe Froguel
Estimation Of Newborn Risk For Child Or Adolescent Obesity:Lessons From Longitudinal Birth Cohorts, Anita Morandi, David Meyre, Stephane Lobbens, Ken Kleinman, Marika Kaakinen, Sheryl L. Rifas-Shiman, Vincent Vatin, Stefan Gaget, Anneli Pouta, Anna-Liisa Hartikainen, Jaana Laitinen, Matthew W. Gillman, Marjo-Riitta Jarvelin, Philippe Froguel
Public Health Department Faculty Publication Series
OBJECTIVES:
Prevention of obesity should start as early as possible after birth. We aimed to build clinically useful equations estimating the risk of later obesity in newborns, as a first step towards focused early prevention against the global obesity epidemic.
METHODS:
We analyzed the lifetime Northern Finland Birth Cohort 1986 (NFBC1986) (N = 4,032) to draw predictive equations for childhood and adolescent obesity from traditional risk factors (parental BMI, birth weight, maternal gestational weight gain, behaviour and social indicators), and a genetic score built from 39 BMI/obesity-associated polymorphisms. We performed validation analyses in a retrospective cohort of 1,503 Italian children …