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Full-Text Articles in Medicine and Health Sciences

Effect Of Renin-Angiotensin System Inhibitors On Acute Kidney Injury Among Patients Undergoing Cardiac Surgery: A Review And Meta-Analysis, Han Zhou, Jingui Xie, Zhichao Zheng, Oon Cheong Ooi, Haidong Luo Dec 2021

Effect Of Renin-Angiotensin System Inhibitors On Acute Kidney Injury Among Patients Undergoing Cardiac Surgery: A Review And Meta-Analysis, Han Zhou, Jingui Xie, Zhichao Zheng, Oon Cheong Ooi, Haidong Luo

Research Collection Lee Kong Chian School Of Business

Acute kidney injury (AKI) is a frequent complication of cardiac surgery, which can lead to higher mortality and long-term renal function impairment. The effect of perioperative renin-angiotensin system inhibitors (RASi) therapy on AKI incidence in patients undergoing cardiac surgery remains controversial. We reviewed related studies in PubMed, Scopus, and Cochrane Library from inception to February 2020. Two randomized controlled trials and 21 cohort studies were included in the meta-analysis, involving 76,321 participants. The pooled odds ratio and 95% confidence interval were calculated using the DerSimonian and Laird random-effects model. The results showed no significant association between perioperative RASi therapy and …


Channel Integration Services In Online Healthcare Communities, Anqi Zhao, Qian Tang Dec 2021

Channel Integration Services In Online Healthcare Communities, Anqi Zhao, Qian Tang

Research Collection School Of Computing and Information Systems

In online healthcare communities, channel integration services have become the bridge between online and offline channels, enabling patients to easily migrate across channels. Different from pure online services, online-to-offline (On2Off) and offline-to-online (Off2On) channel integration services involve both channels. This study examines the interrelationships between pure online services and channel integration services. Using a panel dataset composed of data from an online healthcare community, we find that pure online services decrease patients’ demand for On2Off integration services but increase their use of Off2On integration services. Our findings suggest that providing healthcare services online can reduce online patients’ needs to visit …


Themes, Communities And Influencers Of Online Probiotics Chatter: A Retrospective Analysis From 2009-2017, Santosh Vijaykumar, Aravind Sesagiri Raamkumar, Kristofor Mccarty, Cuthbert Mutumbwa, Jawwad Mustafa, Cyndy Au Oct 2021

Themes, Communities And Influencers Of Online Probiotics Chatter: A Retrospective Analysis From 2009-2017, Santosh Vijaykumar, Aravind Sesagiri Raamkumar, Kristofor Mccarty, Cuthbert Mutumbwa, Jawwad Mustafa, Cyndy Au

Research Collection Lee Kong Chian School Of Business

We build on recent examinations questioning the quality of online information about probiotic products by studying the themes of content, detecting virtual communities and identifying key influencers in social media using data science techniques. We conducted topic modelling (n = 36,715 tweets) and longitudinal social network analysis (n = 17,834 tweets) of probiotic chatter on Twitter from 2009–17. We used Latent Dirichlet Allocation (LDA) to build the topic models and network analysis tool Gephi for building yearly graphs. We identified the top 10 topics of probiotics-related communication on Twitter and a constant rise in communication activity. However the number of …


Prediction Of Synthetic Lethal Interactions In Human Cancers Using Multi-View Graph Auto-Encoder, Zhifeng Hao, Di Wu, Yuan Fang, Min Wu, Ruichu Cai, Xiaoli Li Oct 2021

Prediction Of Synthetic Lethal Interactions In Human Cancers Using Multi-View Graph Auto-Encoder, Zhifeng Hao, Di Wu, Yuan Fang, Min Wu, Ruichu Cai, Xiaoli Li

Research Collection School Of Computing and Information Systems

Synthetic lethality (SL) is a very important concept for the development of targeted anticancer drugs. However, experimental methods for SL detection often suffer from various issues like high cost and low consistency across cell lines. Hence, computational methods for predicting novel SLs have recently emerged as complements for wet-lab experiments. In addition, SL data can be represented as a graph where nodes are genes and edges are the SL interactions. It is thus motivated to design advanced graph-based machine learning algorithms for SL prediction. In this paper, we propose a novel SL prediction method using Multi-view Graph Auto-Encoder (SLMGAE). We …


Covid-19 One Year On: Security And Privacy Review Of Contact Tracing Mobile Apps, Wei Yang Ang, Lwin Khin Shar Oct 2021

Covid-19 One Year On: Security And Privacy Review Of Contact Tracing Mobile Apps, Wei Yang Ang, Lwin Khin Shar

Research Collection School Of Computing and Information Systems

The ongoing COVID-19 pandemic caused 3.8 million deaths since December 2019. At the current vaccination pace, this global pandemic could persist for several years. Throughout the world, contact tracing (CT) apps were developed, which play a significant role in mitigating the spread of COVID-19. This work examines the current state of security and privacy landscape of mobile CT apps. Our work is the first attempt, to our knowledge, which provides a comprehensive analysis of 70 CT apps used worldwide as of year Q1 2021. Among other findings, we observed that 80% of them may have handled sensitive data without adequate …


Constrained Contrastive Distribution Learning For Unsupervised Anomaly Detection And Localisation In Medical Images, Yu Tian, Guansong Pang, Fengbei Liu, Yuanhong Chen, Seon Ho Shin, Johan W. Verjans, Rajvinder Singh Oct 2021

Constrained Contrastive Distribution Learning For Unsupervised Anomaly Detection And Localisation In Medical Images, Yu Tian, Guansong Pang, Fengbei Liu, Yuanhong Chen, Seon Ho Shin, Johan W. Verjans, Rajvinder Singh

Research Collection School Of Computing and Information Systems

Unsupervised anomaly detection (UAD) learns one-class classifiers exclusively with normal (i.e., healthy) images to detect any abnormal (i.e., unhealthy) samples that do not conform to the expected normal patterns. UAD has two main advantages over its fully supervised counterpart. Firstly, it is able to directly leverage large datasets available from health screening programs that contain mostly normal image samples, avoiding the costly manual labelling of abnormal samples and the subsequent issues involved in training with extremely class-imbalanced data. Further, UAD approaches can potentially detect and localise any type of lesions that deviate from the normal patterns. One significant challenge faced …


Precision Public Health Campaign: Delivering Persuasive Messages To Relevant Segments Through Targeted Advertisements On Social Media, Jisun An, Haewoon Kwak, Hanya M. Qureshi, Ingmar Weber Sep 2021

Precision Public Health Campaign: Delivering Persuasive Messages To Relevant Segments Through Targeted Advertisements On Social Media, Jisun An, Haewoon Kwak, Hanya M. Qureshi, Ingmar Weber

Research Collection School Of Computing and Information Systems

Although established marketing techniques have been applied to design more effective health campaigns, more often than not, the same message is broadcasted to large populations, irrespective of unique characteristics. As individual digital device use has increased, so have individual digital footprints, creating potential opportunities for targeted digital health interventions. We propose a novel precision public health campaign framework to structure and standardize the process of designing and delivering tailored health messages to target particular population segments using social media–targeted advertising tools. Our framework consists of five stages: defining a campaign goal, priority audience, and evaluation metrics; splitting the target audience …


Recent Advances In Network-Based Methods For Disease Gene Prediction, Sezin Kircali Ata, Min Wu, Yuan Fang, Ou-Yang Le, Chee Keong Kwoh, Xiao-Li Li Jul 2021

Recent Advances In Network-Based Methods For Disease Gene Prediction, Sezin Kircali Ata, Min Wu, Yuan Fang, Ou-Yang Le, Chee Keong Kwoh, Xiao-Li Li

Research Collection School Of Computing and Information Systems

Disease-gene association through Genome-wide association study (GWAS) is an arduous task for researchers. Investigating single nucleotide polymorphisms (SNPs) that correlate with specific diseases needs statistical analysis of associations. Considering the huge number of possible mutations, in addition to its high cost, another important drawback of GWAS analysis is the large number of false-positives. Thus, researchers search for more evidence to cross-check their results through different sources. To provide the researchers with alternative and complementary low-cost disease-gene association evidence, computational approaches come into play. Since molecular networks are able to capture complex interplay among molecules in diseases, they become one of …


Knowledge And Anxiety About Covid-19 In The State Of Qatar, And The Middle East And North Africa Region—A Cross Sectional Study, Sathyanarayanan Doraiswamy, Sohaila Cheema, Maisonneuve Patrick, Amit Abraham, Ingmar Weber, Jisun An, Albert B. Lowenfels, Ravinder Mamtani Jun 2021

Knowledge And Anxiety About Covid-19 In The State Of Qatar, And The Middle East And North Africa Region—A Cross Sectional Study, Sathyanarayanan Doraiswamy, Sohaila Cheema, Maisonneuve Patrick, Amit Abraham, Ingmar Weber, Jisun An, Albert B. Lowenfels, Ravinder Mamtani

Research Collection School Of Computing and Information Systems

While the coronavirus disease 2019 (COVID-19) pandemic wreaked havoc across the globe, we have witnessed substantial mis- and disinformation regarding various aspects of the disease. We conducted a cross-sectional study using a self-administered questionnaire for the general public (recruited via social media) and healthcare workers (recruited via email) from the State of Qatar, and the Middle East and North Africa region to understand the knowledge of and anxiety levels around COVID-19 (April–June 2020) during the early stage of the pandemic. The final dataset used for the analysis comprised of 1658 questionnaires (53.0% of 3129 received questionnaires; 1337 [80.6%] from the …


Technology And Sustainability: The New Business Playing Field, Havovi Joshi May 2021

Technology And Sustainability: The New Business Playing Field, Havovi Joshi

Asian Management Insights

Two topics that have consistently cropped up in conversations among business leaders during the pandemic are technology, in the context of the pervasiveness and quickening pace of digital transformation, and sustainability, especially how we should be doing business without harming the environment and society. The collective belief is that both topics will continue to rise on the world’s agenda, reshaping entire industries while creating new ones. They have changed the way of doing business. So what does the new playbook look like?


Immigrant Families' Health-Related Information Behavior On Instant Messaging Platforms: Health-Related Information Exchange In Immigrant Family Groups On Instant Messaging Platforms, Lev Poretski, Taamannae Taabassum, Anthony Tang May 2021

Immigrant Families' Health-Related Information Behavior On Instant Messaging Platforms: Health-Related Information Exchange In Immigrant Family Groups On Instant Messaging Platforms, Lev Poretski, Taamannae Taabassum, Anthony Tang

Research Collection School Of Computing and Information Systems

For immigrant families, instant messaging family groups are a common platform forsharing and discussing health-related information. Immigrants often maintain contact with their family abroad and trust information in shared IM family groups more than the information from local authorities and sources. In this study, we aimed to understand health-related information behaviors of immigrant families in their IM family groups. Based on the interviews with 6 participants from immigrant families to Canada, we found that immigrant families’ discourse on IM platforms is motivated by love and care for other family members. The families used local and international sources of information, judged …


Digital Sustainability And Its Implications For Finance And Climate Change, Gerard George, Simon J.D. Schillebeeckx Apr 2021

Digital Sustainability And Its Implications For Finance And Climate Change, Gerard George, Simon J.D. Schillebeeckx

Research Collection Lee Kong Chian School Of Business

As the pandemic forced the entire world to a virtual standstill, nature revived a little. The US emitted 10.3% less CO2 in 2020 than in 2019 and other regions similarly experienced emission declines. Depending on the source, global carbon emissions were down between 4 and 8% in 2020.2 Consumers globally have expressed more concern about sustainability, an observation confirmed by large survey research by Accenture, Kantar, Boston Consulting Group (BCG), and Ipsos.3 In its latest Emissions Gap Report4 , the UN Environment Programme (UNEP) explicitly connected the pandemic to climate change, nature loss, and pollution. Besides the acceleration of business …


Enhancing Healthcare Professional And Caregiving Staff Informedness With Data Analytics For Chronic Disease Management, Na Liu, Robert John Kauffman Mar 2021

Enhancing Healthcare Professional And Caregiving Staff Informedness With Data Analytics For Chronic Disease Management, Na Liu, Robert John Kauffman

Research Collection School Of Computing and Information Systems

An important area in healthcare to which data analytics can be applied is chronic disease management. The chronic care model is mostly patient-centric, so patients have been considered as the end users of data analytics. The information needs of healthcare providers have been overlooked. Drawing upon the theory of informedness and the transtheoretical model of health behavior change, we use a multicase study approach to investigate the information needs of different caregiving stakeholders in the spectrum of chronic diseases, and how data analytics can be designed to meet the varying needs of professionals and staff to support their informedness.


Exploring Media Portrayals Of People With Mental Disorders Using Nlp, Swapna Gottipati, Mark Chong, Andrew Wei Kiat Lim, Benny Haryanto Kawidiredjo Feb 2021

Exploring Media Portrayals Of People With Mental Disorders Using Nlp, Swapna Gottipati, Mark Chong, Andrew Wei Kiat Lim, Benny Haryanto Kawidiredjo

Research Collection School Of Computing and Information Systems

Media plays an important role in creating an impact in society. Several studies show that news media and entertainment channels, at times may create overwhelming images of the mental illness that emphasize criminality and dangerousness. The consequences of such negative impact may impact the audience with stigma and on the other hand, they impair the self-esteem and help-seeking behavior of the people with mental disorders. This is the first study to examine the Singapore media’s portrayal of persons with mental disorders (MDs) using text analytics and natural language processing. To date, most studies on media portrayal of people with MDs …


Analyzing Tweets On New Norm: Work From Home During Covid-19 Outbreak, Swapna Gottipati, Kyong Jin Shim, Hui Hian Teo, Karthik Nityanand, Shreyansh Shivam Jan 2021

Analyzing Tweets On New Norm: Work From Home During Covid-19 Outbreak, Swapna Gottipati, Kyong Jin Shim, Hui Hian Teo, Karthik Nityanand, Shreyansh Shivam

Research Collection School Of Computing and Information Systems

The COVID-19 pandemic triggered a large-scale work-from-home trend globally in recent months. In this paper, we study the phenomenon of “work-from-home” (WFH) by performing social listening. We propose an analytics pipeline designed to crawl social media data and perform text mining analyzes on textual data from tweets scrapped based on hashtags related to WFH in COVID-19 situation. We apply text mining and NLP techniques to analyze the tweets for extracting the WFH themes and sentiments (positive and negative). Our Twitter theme analysis adds further value by summarizing the common key topics, allowing employers to gain more insights on areas of …


Rapid Transition Of A Technical Course From Face-To-Face To Online, Swapna Gottipatti, Venky Shankaraman Jan 2021

Rapid Transition Of A Technical Course From Face-To-Face To Online, Swapna Gottipatti, Venky Shankaraman

Research Collection School Of Computing and Information Systems

Just like most universities around the world, the senior management at Singapore Management University decided to move all courses to a virtual, online, synchronous mode, giving instructors a very short notice period—one week—to make this transition. In this paper, we describe the challenges, practical solutions adopted, and the lessons learnt in rapidly transitioning a face-to-face Master’s degree course in Text Analytics and Applications into a virtual, online, course format that could deliver a quality learning experience.