Medicine and Health Sciences Commons^™

Effect Of Impeller Submergence On Power Dissipation And Solids Suspension In Mixing Systems Equipped With Pitch-Blade Turbines, Yufeng Song

Theses

Mixing and dispersion of solids in a liquid is a process frequently encountered in the pharmaceutical industry and often conducted in cylindrical baffled tanks stirred by mechanical impellers. In operations where the liquid level is decreased (as often which emptying the tank) the process must be stopped when the solids are no longer suspended. In this work, the minimum agitation to suspend solids (Njs) when the liquid level was lowered, and the impeller submergence S_b changed as a result were determined for the case of a six-blade, pitch-blade turbine (6-PBT) impeller. The power consumed by the impeller …

Experimental Determination Of Solids Suspension With Angled Impeller In A Pharmaceutical Mixing Vessel, Yingxi Tang

Theses

Angled-mounted impellers are commonly used in a number of pharmaceutical industry applications, from laboratory reactors to full-scale tanks. In these systems, the impeller is not centrally and vertically mounted, as in most stirred vessels, but it enters the vessel, and is therefore immersed in the fluid, at an angle from the vertical. This arrangement provides some baffling effects that would not otherwise exist if the impeller was centrally mounted.

One common requirement for such systems is that they are capable of suspending small solids dispersed in the liquid. Therefore, it is critical to know the value of the minimum agitation …