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Articles 1 - 30 of 226
Full-Text Articles in Medicine and Health Sciences
Research News: 2012, No. 2, University Of Mississippi. School Of Pharmacy
Research News: 2012, No. 2, University Of Mississippi. School Of Pharmacy
Research News: Grants and Publications (2000-2014)
Grants and contracts recently awarded
Students Attend Prestigious Professional Leadership Conference, Nathan Pilling
Students Attend Prestigious Professional Leadership Conference, Nathan Pilling
News Releases
Three students from Cedarville University’s inaugural Doctor of Pharmacy class recently participated in a distinguished, statewide leadership training conference. Jenna Lawhead, from Saint Petersburg, Fla., Jayson Brewin, from Shamong, N.J., and Allison Henry, from Roseville, Minn., were invited to attend the Ohio Pharmacists Association’s (OPA) Young Pharmacy Leadership Conference held on Sep. 29, 2012 in Columbus, OH.
Pharmacy Professor Collaborates In Valuable Drug Research, Nathan Pilling
Pharmacy Professor Collaborates In Valuable Drug Research, Nathan Pilling
News Releases
Natural products make up a sizable portion of the drugs Americans use every day. What makes these products effective? Are there other plants we haven’t discovered yet that could help us control diseases such as cancer and malaria? These are the questions Denise Simpson, Ph.D., is focused on answering through her research.
Treatment Of Klebsiella Pneumoniae Carbapenemase (Kpc) Infections: A Review Of Published Case Series And Case Reports, Grace C. Lee, David S. Burgess
Treatment Of Klebsiella Pneumoniae Carbapenemase (Kpc) Infections: A Review Of Published Case Series And Case Reports, Grace C. Lee, David S. Burgess
Pharmacy Practice and Science Faculty Publications
The emergence of Klebsiella pneumoniae carbapenemases (KPCs) producing bacteria has become a significant global public health challenge while the optimal treatment remains undefined. We performed a systematic review of published studies and reports of treatment outcomes of KPC infections using MEDLINE (2001-2011). Articles or cases were excluded if one of the following was fulfilled: no individual patient data provided, no treatment regimen specified, no treatment outcome specified, report of colonization, or greater than three antibiotics were used to treat the KPC infection. Data extracted included patient demographics, site of infection, organism, KPC subtype, antimicrobial therapy directed at KPC-infection, and treatment …
Proliferation Of Genetically Modified Human Cells On Electrospun Nanofiber Scaffolds., Mandula Borjigin, Bryan Strouse, Rohina A. Niamat, Pawel Bialk, Chris Eskridge, Jingwei Xie, Eric B. Kmiec
Proliferation Of Genetically Modified Human Cells On Electrospun Nanofiber Scaffolds., Mandula Borjigin, Bryan Strouse, Rohina A. Niamat, Pawel Bialk, Chris Eskridge, Jingwei Xie, Eric B. Kmiec
Journal Articles: Pharmaceutical Sciences
Gene editing is a process by which single base mutations can be corrected, in the context of the chromosome, using single-stranded oligodeoxynucleotides (ssODNs). The survival and proliferation of the corrected cells bearing modified genes, however, are impeded by a phenomenon known as reduced proliferation phenotype (RPP); this is a barrier to practical implementation. To overcome the RPP problem, we utilized nanofiber scaffolds as templates on which modified cells were allowed to recover, grow, and expand after gene editing. Here, we present evidence that some HCT116-19, bearing an integrated, mutated enhanced green fluorescent protein (eGFP) gene and corrected by gene editing, …
Heart Failure Transition Of Care Program: The Pharmacist’S Role In Reducing Readmissions, Joseph Favatella, Pharmd Candidate 2013, Joanne Heil, Pharmd, Bcps
Heart Failure Transition Of Care Program: The Pharmacist’S Role In Reducing Readmissions, Joseph Favatella, Pharmd Candidate 2013, Joanne Heil, Pharmd, Bcps
College of Pharmacy Faculty Papers
Presented at: ASHP Mid-Year Clinical Meeting in Las Vegas.
Introduction & Background
Current Trends1
•Approximately 19.6% of Medicare patients are readmitted to the hospital within 30 days
•These readmissions accounted for $15 billion of Medicare spending in 2009
Changes Coming
•As part of the Affordable Care Act, Medicare will not be reimbursing hospitals for patients readmitted within 30 days of discharge
•Hospitals have already begun improving discharge protocols to provide a greater continuity of care and minimize the financial loss of future readmissions
A Model2
•Boston University Medical Center's Re-Engineered Discharge (RED) was the first program to improve …
The Use Of Glucarpidase In An Open-Label Treatment Protocol As Adjunctive Treatment For A Patient With Delayed Methotrexate Elimination, Cheryl A. Abbas, Pharmd, Anne Marie Valorie-Oberle, Bs, Pharmd, Bcop
The Use Of Glucarpidase In An Open-Label Treatment Protocol As Adjunctive Treatment For A Patient With Delayed Methotrexate Elimination, Cheryl A. Abbas, Pharmd, Anne Marie Valorie-Oberle, Bs, Pharmd, Bcop
College of Pharmacy Faculty Papers
Presented at: ASHP Clinical MidYear Meeting in Las Vegas.
Background
Methotrexate (MTX)
- Cytotoxic agent that competitively inhibits dihydrofolate reductase (DHFR), the intracellular enzyme responsible for converting folic acid to reduced folate inhibitors, necessary for DNA synthesis
- Used since 1948 in the treatment of various malignancies and as a disease-modifying agent in rheumatoid arthritis and psoriasis
- High-dose mexthotrexate (HDMTX) began in 1960s solely or in combination with other chemotherapeutic agents
Methotrexate Toxicity
- Almost exclusively cleared through the kidneys
- Precipitation of drug occurs in the renal tubules
- Prolonged elevations of systemic MTX concentrations results in potential serious toxicity
- Increased use of HDMTX …
Septohippocampal Gabaergic Neurons Mediate The Altered Behaviors Induced By N-Methyl-D-Aspartate Receptor Antagonists., Jingyi Ma, Siew Kian Tai, L Stan Leung
Septohippocampal Gabaergic Neurons Mediate The Altered Behaviors Induced By N-Methyl-D-Aspartate Receptor Antagonists., Jingyi Ma, Siew Kian Tai, L Stan Leung
Physiology and Pharmacology Publications
We hypothesize that selective lesion of the septohippocampal GABAergic neurons suppresses the altered behaviors induced by an N-methyl-D-aspartate (NMDA) receptor antagonist, ketamine or MK-801. In addition, we hypothesize that septohippocampal GABAergic neurons generate an atropine-resistant theta rhythm that coexists with an atropine-sensitive theta rhythm in the hippocampus. Infusion of orexin-saporin (ore-SAP) into the medial septal area decreased parvalbumin-immunoreactive (GABAergic) neurons by ~80%, without significantly affecting choline-acetyltransferase-immunoreactive (cholinergic) neurons. The theta rhythm during walking, or the immobility-associated theta induced by pilocarpine, was not different between ore-SAP and sham-lesion rats. Walking theta was, however, more disrupted by atropine sulfate in ore-SAP than …
Limited Sampling Estimates Of Epigallocatechin Gallate Exposures In Cirrhotic And Noncirrhotic Patients With Hepatitis C After Single Oral Doses Of Green Tea Extract., Dina Halegoua-De Marzio, Walter K. Kraft, Constantine Daskalakis, Xie Ying, Roy L Hawke, Victor J. Navarro
Limited Sampling Estimates Of Epigallocatechin Gallate Exposures In Cirrhotic And Noncirrhotic Patients With Hepatitis C After Single Oral Doses Of Green Tea Extract., Dina Halegoua-De Marzio, Walter K. Kraft, Constantine Daskalakis, Xie Ying, Roy L Hawke, Victor J. Navarro
Division of Gastroenterology and Hepatology Faculty Papers
BACKGROUND: Epigallocatechin-3-gallate (EGCG) has antiangiogenic, antioxidant, and antifibrotic properties that may have therapeutic potential for the treatment of cirrhosis induced by hepatitis C virus (HCV). However, cirrhosis might affect EGCG disposition and augment its reported dose-dependent hepatotoxic potential.
OBJECTIVE: The safety, tolerability, and disposition of a single oral dose of EGCG in cirrhotic patients with HCV were examined in an exploratory fashion.
METHODS: Eleven patients with hepatitis C and detectable viremia were enrolled. Four had Child-Pugh (CP) class A cirrhosis, 4 had Child-Pugh class B cirrhosis, and 3 were noncirrhotic. After a single oral dose of green tea extract 400 …
Pharmacokinetics And Brain Uptake In The Rhesus Monkey Of A Fusion Protein Of Arylsulfatase A And A Monoclonal Antibody Against The Human Insulin Receptor, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui, Rachita K. Sumbria, William M. Pardridge
Pharmacokinetics And Brain Uptake In The Rhesus Monkey Of A Fusion Protein Of Arylsulfatase A And A Monoclonal Antibody Against The Human Insulin Receptor, Ruben J. Boado, Jeff Zhiqiang Lu, Eric Ka-Wai Hui, Rachita K. Sumbria, William M. Pardridge
Pharmacy Faculty Articles and Research
Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder of the brain caused by mutations in the gene encoding the lysosomal sulfatase, arylsulfatase A (ASA). It is not possible to treat the brain in MLD with recombinant ASA, because the enzyme does not cross the blood-brain barrier (BBB). In the present investigation, a BBB-penetrating IgG-ASA fusion protein is engineered and expressed, where the ASA monomer is fused to the carboxyl terminus of each heavy chain of an engineered monoclonal antibody (MAb) against the human insulin receptor (HIR). The HIRMAb crosses the BBB via receptor-mediated transport on the endogenous BBB insulin receptor, …
Anti-Cocaine Compositions And Treatment, Donald W. Landry, Joanne Macdonald, Shi-Xiang Deng, Chang-Guo Zhan, Daquan Gao, James H. Woods, Roger K. Sunahara, Diwahar L. Narasimhan, Victor Yang, Mei-Chuan Holden Ko, John J. Tesmer, Tien-Yi Lee, Young Min Kwon
Anti-Cocaine Compositions And Treatment, Donald W. Landry, Joanne Macdonald, Shi-Xiang Deng, Chang-Guo Zhan, Daquan Gao, James H. Woods, Roger K. Sunahara, Diwahar L. Narasimhan, Victor Yang, Mei-Chuan Holden Ko, John J. Tesmer, Tien-Yi Lee, Young Min Kwon
Pharmaceutical Sciences Faculty Patents
Embodiments of the invention disclosed herein generally relate to anti-cocaine therapeutics. Specifically, some embodiments of the invention relate to highly efficient, thermostable, and long-lasting cocaine esterase (CocE) mutants that can protect against the toxic and reinforcing effects of cocaine in subjects. Provided herein are mutant CocE polypeptides displaying thermostable esterase activity. Also provided are methods of treating cocaine-induced conditions in a subject in need via administration of mutant CocE as well as methods for high-throughput screening of candidate esterase polypeptides.
Cyclooxygenase-2 Inhibition Attenuates Abdominal Aortic Aneurysm Progression In Hyperlipidemic Mice, Sarbani Ghoshal, Charles D Loftin
Cyclooxygenase-2 Inhibition Attenuates Abdominal Aortic Aneurysm Progression In Hyperlipidemic Mice, Sarbani Ghoshal, Charles D Loftin
Pharmaceutical Sciences Faculty Publications
Abdominal aortic aneurysms (AAAs) are a chronic inflammatory disease that increase the risk of life-threatening aortic rupture. In humans, AAAs have been characterized by increased expression of cyclooxygenase-2 and the inactivation of COX-2 prior to disease initiation reduces AAA incidence in a mouse model of the disease. The current study examined the effectiveness of selective cyclooxygenase-2 (COX-2) inhibition on reducing AAA progression when administered after the initiation of AAA formation. AAAs were induced in hyperlipidemic apolipoprotein E-deficient mice by chronic angiotensin II (AngII) infusion and the effect of treatment with the COX-2 inhibitor celecoxib was examined when initiated at different …
Reviewing The American University Law Review On Extraterritoriality: A Critical Response To Viki Economides, Note, Tianrui Group Co. V. Itc: The Dubious Status Of Extraterritoriality And The Domestic Industry Requirement Requirement Of Section 337(Link), Jonathan Stroud
Articles in Law Reviews & Other Academic Journals
Recently, the Federal Circuit upheld the Commission’s decision to exclude goods based on a trade secret violation that largely happened abroad. The American University Law Review critiqued that decision on two grounds: First, that a presumption against extraterritorial application of U.S. law applied; and second, that licensing alone could not establish a domestic industry. The American University Law Review's critique remains incomplete, however, as the Federal Circuit correctly decided the case for at least two reasons. first, the Federal Circuit correctly applied the “extraterritorial presumption” canon of construction; and second, the recent Federal Circuit decision in InterDigital Communications LLC v. …
Indole Compounds And Their Use As Radiation Sensitizing Agents And Chemotherapeutic Agents, Peter A. Crooks, Thirupathi R. Yerramreddy, Narsimha Reddy Penthala, Michael L. Freeman, Sekhar R. Konjeti
Indole Compounds And Their Use As Radiation Sensitizing Agents And Chemotherapeutic Agents, Peter A. Crooks, Thirupathi R. Yerramreddy, Narsimha Reddy Penthala, Michael L. Freeman, Sekhar R. Konjeti
Pharmaceutical Sciences Faculty Patents
Indole derivatives that are useful in the treatment of cancer as a chemotherapeutic agent or radiosensitizing agent.
Molecular Mechanism For Depolarization-Induced Modulation Of Kv Channel Closure, Alain J. Labro, Jerome J. Lacroix, Carlos A. Villalba-Galea, Dirk J. Snyders, Francisco Bezanilla
Molecular Mechanism For Depolarization-Induced Modulation Of Kv Channel Closure, Alain J. Labro, Jerome J. Lacroix, Carlos A. Villalba-Galea, Dirk J. Snyders, Francisco Bezanilla
School of Pharmacy Faculty Articles
Voltage-dependent potassium (Kv) channels provide the repolarizing power that shapes the action potential duration and helps control the firing frequency of neurons. The K(+) permeation through the channel pore is controlled by an intracellularly located bundle-crossing (BC) gate that communicates with the voltage-sensing domains (VSDs). During prolonged membrane depolarizations, most Kv channels display C-type inactivation that halts K(+) conduction through constriction of the K(+) selectivity filter. Besides triggering C-type inactivation, we show that in Shaker and Kv1.2 channels (expressed in Xenopus laevis oocytes), prolonged membrane depolarizations also slow down the kinetics of VSD deactivation and BC gate closure during the …
North American Bioactive Plants For Human Health And Performance, Maria Pontes Ferreira, Fidji Gendron, Katrina C. Mcclure, Kelly Kindscher
North American Bioactive Plants For Human Health And Performance, Maria Pontes Ferreira, Fidji Gendron, Katrina C. Mcclure, Kelly Kindscher
Nutrition and Food Science Faculty Research Publications
Native and naturalized bioactive plants of the Canadian and American temperate biome are examined for their health and performance enhancement properties. Some of these plants are now being used as natural health products, and many have a long history as traditional foods and/or medicines with indigenous groups. This paper reviews the medicinal/cultural uses and bioactive properties of selected plant families: the Holly family (Aquifoliaceae) as stimulants, the Celery family (Apiaceae) as normoglycemic aids and analgesics, the Ginseng family (Araliaceae) as energy- boosting aids, the Sunflower family (Compositae) as anti-inflammatory aids, and the Legume family (Fabaceae) and Nightshade family (Solanaceae) as …
Pharmacy Law Brief: Contemporary Legal Issues For Leadership In Non-Profits - Ii, Joseph L. Fink Iii
Pharmacy Law Brief: Contemporary Legal Issues For Leadership In Non-Profits - Ii, Joseph L. Fink Iii
Pharmacy Practice and Science Faculty Publications
No abstract provided.
Chronic Hepatitis B And C Co-Infection Increased All-Cause Mortality In Haart-Naive Hiv Patients In Northern Thailand, N. Tsuchiya, P. Pathipvanich, A. Rojanawiwat, N. Wichukchinda, I. Koga, M. Koga, W. Auwanit, P. E. Kilgore, K. Ariyoshi, P. Sawanpanyalert
Chronic Hepatitis B And C Co-Infection Increased All-Cause Mortality In Haart-Naive Hiv Patients In Northern Thailand, N. Tsuchiya, P. Pathipvanich, A. Rojanawiwat, N. Wichukchinda, I. Koga, M. Koga, W. Auwanit, P. E. Kilgore, K. Ariyoshi, P. Sawanpanyalert
Department of Pharmacy Practice
A total of 755 highly active antiretroviral therapy (HAART)-naive HIV-infected patients were enrolled at a government hospital in Thailand from 1 June 2000 to 15 October 2002. Census date of survival was on 31 October 2004 or the date of HAART initiation. Of 700 (92.6%) patients with complete data, the prevalence of hepatitis B virus (HBV) surface antigen and anti-hepatitis C virus (HCV) antibody positivity was 11.9% and 3.3%, respectively. Eight (9.6%) HBV co-infected patients did not have anti-HBV core antibody (anti-HBcAb). During 1166.7 person-years of observation (pyo), 258 (36.9%) patients died [22.1/100 pyo, 95% confidence interval (CI) 16.7–27.8]. HBV …
Dysregulation Of Mir-31 And Mir-21 Induced By Zinc Deficiency Promotes Esophageal Cancer, Hansjuerg Alder, Cristian Taccioli, Hongping Chen, Yubao Jiang, Karl Smalley, Paolo Fadda, Hatice G. Ozer, Kay Huebner, John Farber, Carlo M. Croce, Louise Fong
Dysregulation Of Mir-31 And Mir-21 Induced By Zinc Deficiency Promotes Esophageal Cancer, Hansjuerg Alder, Cristian Taccioli, Hongping Chen, Yubao Jiang, Karl Smalley, Paolo Fadda, Hatice G. Ozer, Kay Huebner, John Farber, Carlo M. Croce, Louise Fong
Department of Pharmacology and Experimental Therapeutics Faculty Papers
Presented at: Hallmarks and Cancer Conference, October 29-31 in San Francisco.
And AICR Annual Meeting, November 1-2, 2012.
Dietary zinc (Zn) deficiency (ZD) in rats induces an inflammatory gene signature that fuels esophageal squamous cell cancer (ESCC). Using nanoStringTM technology, we show that the inflammation is accompanied by altered expression of specific microRNAs in esophagus, as well as skin, lung, pancreas, liver, prostate, and PBMC, predictive of disease development. Particularly, the ZD esophagus has a microRNA signature resembling human ESCC/tongue SCC miRNAomes with overexpression of miR-31 and miR-21 and downregulation of their respective tumor suppressor targets PPP2R2A and …
A Human Phospholipid Phosphatase Activated By A Transmembrane Control Module, Christian R. Halaszovich, Michael G. Leitner, Angeliki Mavrantoni, Audrey Le, Ludivine Frezza, Anja Feuer, Daniela N. Schreiber, Carlos A. Villalba-Galea, Dominik Oliver
A Human Phospholipid Phosphatase Activated By A Transmembrane Control Module, Christian R. Halaszovich, Michael G. Leitner, Angeliki Mavrantoni, Audrey Le, Ludivine Frezza, Anja Feuer, Daniela N. Schreiber, Carlos A. Villalba-Galea, Dominik Oliver
School of Pharmacy Faculty Articles
In voltage-sensitive phosphatases (VSPs), a transmembrane voltage sensor domain (VSD) controls an intracellular phosphoinositide phosphatase domain, thereby enabling immediate initiation of intracellular signals by membrane depolarization. The existence of such a mechanism in mammals has remained elusive, despite the presence of VSP-homologous proteins in mammalian cells, in particular in sperm precursor cells. Here we demonstrate activation of a human VSP (hVSP1/TPIP) by an intramolecular switch. By engineering a chimeric hVSP1 with enhanced plasma membrane targeting containing the VSD of a prototypic invertebrate VSP, we show that hVSP1 is a phosphoinositide-5-phosphatase whose predominant substrate is PI(4,5)P(2). In the chimera, enzymatic activity …
A Pharmacogenomic And Protein Analysis Of Human Lacrimal Fluid In Varying Age Groups, Jayson M. Brewin, Daniel C. James, Neil B. Klinger, Jenna G. Lawhead, Nathaniel J. Luce, Lindsay N. Florkey, Rocco J. Rotello
A Pharmacogenomic And Protein Analysis Of Human Lacrimal Fluid In Varying Age Groups, Jayson M. Brewin, Daniel C. James, Neil B. Klinger, Jenna G. Lawhead, Nathaniel J. Luce, Lindsay N. Florkey, Rocco J. Rotello
Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session
Proteins are large biological molecules located within all cells. They are considered the basic functional components of cells that allow them to operate appropriately. Genes consist of both DNA and RNA, and are the cellular components that code for the proteins. A biomarker is any cellular component that is an indication of a biological state. Therefore, genetic and protein biomarkers are specific genes and proteins, respectively, present in cells that indicate a specific biological state of a cell. Identification of proteins and genetic biomarkers in relative quantities has been found to reflect various disease states and age groups in humans. …
Breast Cancer Vaccine: Are We There Yet?, Lipika Chablani
Breast Cancer Vaccine: Are We There Yet?, Lipika Chablani
Pharmacy Faculty/Staff Publications
In lieu of an abstract, here is the article's first paragraph:
Breast cancer is the most fatal form of cancer for female population worldwide. National Cancer Institute (NCI) estimates 226,870 females and 2,190 males to be diagnosed with breast cancer in the United States by the end of 2012. The estimated death toll for this year includes 39,510 females and 410 males, as reported by NCI. Statistics state that 1 in every 8 females will be diagnosed with breast cancer during her lifetime. These alarming numbers have provoked a large number of scientists to contribute towards the fight against breast …
Student Influences In Choosing Pharmacy, Veronica Asomani-Amoah, Kingsley Njangnso, Lauren Petry, Colin Sprague, Molly Turner, Douglas C. Anderson, Jeb Ballentine
Student Influences In Choosing Pharmacy, Veronica Asomani-Amoah, Kingsley Njangnso, Lauren Petry, Colin Sprague, Molly Turner, Douglas C. Anderson, Jeb Ballentine
Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session
To determine the race, cultural background, gender, and regional factors on students’ perceptions and influences in choosing pharmacy as a profession on a national scale.
Emergency Contraceptive (Ec) Use In Indigent Populations, Ashley Benjamin, Kasandra Chambers, Melissa Mcnicol, Amy Roy, Kurtis Schultz, April Yoakam, Miriam A. Ansong, Tracy R. Frame
Emergency Contraceptive (Ec) Use In Indigent Populations, Ashley Benjamin, Kasandra Chambers, Melissa Mcnicol, Amy Roy, Kurtis Schultz, April Yoakam, Miriam A. Ansong, Tracy R. Frame
Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session
The indigent population in America is defined as persons who do not have the financial means to support themselves and are below the federal/state poverty line. According to the 2010 United States Census, 13.8% of Americans are living below the poverty line. Indigent populations often rely on the help of others to provide for their basic needs, whether the help of family and friends or government support. Indigent women are disproportionately affected by unwanted, unplanned pregnancies. It is a continuous cycle that plagues families, often causing poverty and an increased dependence on the welfare system. In Medicaid-eligible populations, many women …
Max Dose Opioids: How High Can You Go?, John B. Bossaer, Sarah T. Melton
Max Dose Opioids: How High Can You Go?, John B. Bossaer, Sarah T. Melton
ETSU Faculty Works
Learning Objectives:
- Describe the rationale for the belief that opioids have no maximum dose
- Describe the data supporting the rationale that high doses of opioids increase toxicity
- Describe the data supporting the rationale that high doses of opioids do not improve outcomes
- Identify potential safety concerns with patients taking high doses of opioids
Effects Of Physical Stress And Maturational Changes On Hypothalamic Pituitary Adrenal Axis Function Through Cortisol Analysis, Amy Granger, Allison Henry, Lauren Lilliencrantz, Amanda Smith, Paul Srnis, William Van Schepen, Elisha R. Injeti
Effects Of Physical Stress And Maturational Changes On Hypothalamic Pituitary Adrenal Axis Function Through Cortisol Analysis, Amy Granger, Allison Henry, Lauren Lilliencrantz, Amanda Smith, Paul Srnis, William Van Schepen, Elisha R. Injeti
Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session
Cortisol is a versatile hormone that possesses both catabolic and anabolic functions in the body, such as increasing the blood glucose levels through gluconeogenesis and metabolizing carbohydrates, proteins, and fats.1234 Cortisol levels are controlled by communication of the hyptothalamic-pituitary-adrenal axix (HPA axis). Plasma concentration of cortisol adheres to a diurnal rhythm, meaning that cortisol levels are highest in the morning and taper off throughout the day.
Health Literacy In Community Pharmacy, Sarah Anderson, Cassie Brownfield-Wilson, Kelly Madden, Lindsay Tarleton, Joe Zerka, Aleda M.H. Chen
Health Literacy In Community Pharmacy, Sarah Anderson, Cassie Brownfield-Wilson, Kelly Madden, Lindsay Tarleton, Joe Zerka, Aleda M.H. Chen
Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session
48% of English-speaking patients are unable to obtain, process, understand, and utilize health information, and 30-50% of patients do not correctly adhere to their medications. The combination of chronic disease, poor heath literacy, and poor medication adherence lead to increased health costs and hospitalization
A Comparison Of The Effect Of Intermittent And Continuous Infusion Of Meropenem On The Prevalence Of Nausea In Pediatric Cystic Fibrosis Patients, Marissa Cushing, Juanita A. Draime, Bao-Ngoc Ho, Jordan Nicholls, Bethany Sibbitt, Rebecca Widder, Rebecca J. Gryka, Denise S. Simpson
A Comparison Of The Effect Of Intermittent And Continuous Infusion Of Meropenem On The Prevalence Of Nausea In Pediatric Cystic Fibrosis Patients, Marissa Cushing, Juanita A. Draime, Bao-Ngoc Ho, Jordan Nicholls, Bethany Sibbitt, Rebecca Widder, Rebecca J. Gryka, Denise S. Simpson
Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session
Cystic Fibrosis (CF) is a genetic disease, leading to changes of membrane secretions causing obstruction of smaller airways. CF patients often develop pulmonary infections and require antibiotic treatment. Meropenem is a broad spectrum beta lactam that acts by lysing microbes through interfering with bacterial cell wall synthesis. Although a safe and effective treatment, data on pediatric patients is limited.
Improving Medication Safety In An Independent Community Pharmacy, Kacey Adams, Chris Nguyen, Tara Perkins, Laura Richardson, Heather Rose, Jeffrey D. Lewis
Improving Medication Safety In An Independent Community Pharmacy, Kacey Adams, Chris Nguyen, Tara Perkins, Laura Richardson, Heather Rose, Jeffrey D. Lewis
Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session
Medication errors are often times thought of as a patient receiving a medication that belongs to another patient, but many to do not understand the other areas that are constituted as “medication errors” are much broader. These errors include, but are not limited to, patient receiving the incorrect medication, improper dosing (too large or too small), wrong drug dispensed, incorrect methods of administration, mislabeling, and etc. Medication errors are such an important issue in the United State because it is the most medicated society in history.
Asthma Knowledge, Adherence, And Administration Techniques In Hispanic Caregivers Of Pediatrics, Joshua Arnold, Rachel Culp, Kyle Hultz, Benjamin Robertson, Jon Wilkie, Amy Wuobio, Marty L. Eng, Kelly J. Hiteshew
Asthma Knowledge, Adherence, And Administration Techniques In Hispanic Caregivers Of Pediatrics, Joshua Arnold, Rachel Culp, Kyle Hultz, Benjamin Robertson, Jon Wilkie, Amy Wuobio, Marty L. Eng, Kelly J. Hiteshew
Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session
7.5% of Hispanics in the United States suffer from asthma-related diseases, and Latino children are not as likely to use preventative asthma medications as compared with Caucasians. Educational interventions may reduce the number of visits to emergency-care. The reasons for non-adherence are currently unknown, and discovering these reasons will help to address the problem.