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Full-Text Articles in Medicine and Health Sciences
Target Repurposing For Neglected Diseases, Michael P. Pollastri, Robert K. Campbell
Target Repurposing For Neglected Diseases, Michael P. Pollastri, Robert K. Campbell
Michael Pollastri
Infectious diseases are an enormous burden to global health, and since drug discovery is costly, those infectious diseases that affect the developing world are often not pursued by commercial drug discovery efforts. Therefore, pragmatic means by which new therapeutics can be discovered are needed. One such approach is target repurposing, where pathogen targets are matched with homologous human targets that have been pursued for drug discovery for other indications. In many cases, the medicinal chemistry, structural biology, and biochemistry knowledge around these human targets can be directly repurposed to launch and accelerate new drug discovery efforts against the pathogen targets. …
A Vidcasting Project To Promote The Pharmacist's Role In Public Health, Seena L. Haines, Jenny A. Van Amburgh
A Vidcasting Project To Promote The Pharmacist's Role In Public Health, Seena L. Haines, Jenny A. Van Amburgh
Jenny A. Van Amburgh
Objective. To develop, implement, and assess an Internet-based vidcasting project to promote the pharmacist's role in public health. Design. This was a collaborative effort for 2 different courses taught at 2 different schools of pharmacy. Faculty members created a special instructional design for students to follow in planning, producing, and publishing video public service announcements on the Internet.Assessment. Formative and summative assessments, including course examinations, a grading rubric, student survey, and focus group, were implemented to evaluate student learning and public reaction. Students believed Internet video public service announcements served as a useful reference for patients and professionals, aided in …
Bacterial Resistance To Antibiotics:How It Happens,Why It's Important,And What You Can Do About It., Richard Philp
Bacterial Resistance To Antibiotics:How It Happens,Why It's Important,And What You Can Do About It., Richard Philp
Richard B. Philp
Bacterial resistance to antibiotics has become a major clinical problem exacerbated by the widespread and sometimes inappropriate use of antibiotics. Reasons for its emergence, mechanisms of resistance, types of resistance and appropriate public behaviour to combat the problem are discussed in language accessable to the general public.