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Full-Text Articles in Medicine and Health Sciences

Effects Of Prenatal Cannabis Exposure On Offspring Emotional Development And Stress Response, Alexandra Pritchett Sep 2021

Effects Of Prenatal Cannabis Exposure On Offspring Emotional Development And Stress Response, Alexandra Pritchett

Dissertations, Theses, and Capstone Projects

While cannabis may be used by women during pregnancy, its effects on their offsprings’ developing stress response system are still largely unknown. The binding sites for the active chemicals in cannabis are operational at early time points in fetal development and are expressed in key limbic brain structures. The body’s natural endocannabinoid system serves as an important regulator of the stress response. Longitudinal studies have associated prenatal exposure with increased fearfulness and mood disturbances in offspring, but, despite the growing evidence of emotional dysfunction, there remains a critical gap in knowledge explaining how early prenatal exposure may lead to future …


Genetic Variation And Sex Mediate Differential Responses To ∆-9-Tetrahydrocannabinol Among Inbred Mice, Cory Parks Nov 2020

Genetic Variation And Sex Mediate Differential Responses To ∆-9-Tetrahydrocannabinol Among Inbred Mice, Cory Parks

Theses and Dissertations (ETD)

The plant Cannabis sativa has been used by people for both recreational and medicinal use for thousands of years, but scientific investigation of the plant and its components didn’t begin until the early nineteen hundreds when Cannabis components known as phytocannabinoids were characterized and later isolated. In the 1970’s, ∆9-tetrahydrocannabinol (THC) was isolated and recognized as the major constituent responsible for the psychoactive and intoxicating effects associated with consumption of cannabis. This opened the door for intensive research in the field that lead to the discovery of the endogenous cannabinoid system and its associated receptors, effectors of signaling, and biosynthetic …


Perceived Harms And Benefits Of Parental Cannabis Use, And Parents’ Reports Regarding Harm-Reduction Strategies, Kathleen J. Donoghue Jan 2015

Perceived Harms And Benefits Of Parental Cannabis Use, And Parents’ Reports Regarding Harm-Reduction Strategies, Kathleen J. Donoghue

Theses: Doctorates and Masters

This research focussed on families in which at least one parent was a long-term cannabis user; I explored family members’ perceptions of the benefits and harms of cannabis use and the strategies parents used to minimise cannabis-related harm to themselves and their children. In depth, semi-structured interviews were undertaken with 43 individuals from 13 families, producing a series of family case studies that enabled examination of multiple perspectives within each family. In Study 1, I used an interpretive framework guided by Miles and Huberman’s (1994) thematic content analysis technique to analyse interview data, while study 2 yielded detailed descriptive vignettes …