Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 5 of 5
Full-Text Articles in Medicine and Health Sciences
Decreased Neuroinflammation And Increased Brain Energy Homeostasis Following Environmental Enrichment After Mild Traumatic Brain Injury Is Associated With Improvement In Cognitive Function, Teresita L. Briones, Julie Woods, Magdalena Rogozinska
Decreased Neuroinflammation And Increased Brain Energy Homeostasis Following Environmental Enrichment After Mild Traumatic Brain Injury Is Associated With Improvement In Cognitive Function, Teresita L. Briones, Julie Woods, Magdalena Rogozinska
Wayne State University Associated BioMed Central Scholarship
Abstract
Background
Persistent neuroinflammation and disruptions in brain energy metabolism is commonly seen in traumatic brain injury (TBI). Because of the lack of success of most TBI interventions and the documented benefits of environmental enrichment (EE) in enhancing brain plasticity, here we focused our study on use of EE in regulating injury-induced neuroinflammation and disruptions in energy metabolism in the prefrontal cortex and hippocampus. Adult male Wistar rats were used in the study and randomly assigned to receive either: mild TBI (mTBI) using the controlled cortical injury model or sham surgery. Following surgery, rats from each group were further randomized …
Integrating An Internet-Mediated Walking Program Into Family Medicine Clinical Practice: A Pilot Feasibility Study, David E. Goodrich, Lorraine R. Buis, Adrienne W. Janney, Megan D. Ditty, Christine W. Krause, Kai Zheng, Ananda Sen, Victor J. Strecher, Michael L. Hess, John D. Piette, Caroline R. Richardson
Integrating An Internet-Mediated Walking Program Into Family Medicine Clinical Practice: A Pilot Feasibility Study, David E. Goodrich, Lorraine R. Buis, Adrienne W. Janney, Megan D. Ditty, Christine W. Krause, Kai Zheng, Ananda Sen, Victor J. Strecher, Michael L. Hess, John D. Piette, Caroline R. Richardson
Wayne State University Associated BioMed Central Scholarship
Abstract
Background
Regular participation in physical activity can prevent many chronic health conditions. Computerized self-management programs are effective clinical tools to support patient participation in physical activity. This pilot study sought to develop and evaluate an online interface for primary care providers to refer patients to an Internet-mediated walking program called Stepping Up to Health (SUH) and to monitor participant progress in the program.
Methods
In Phase I of the study, we recruited six pairs of physicians and medical assistants from two family practice clinics to assist with the design of a clinical interface. During Phase II, providers used the …
Evaluating Active U: An Internet-Mediated Physical Activity Program, Lorraine R. Buis, Timothy A. Poulton, Robert G. Holleman, Ananda Sen, Paul J. Resnick, David E. Goodrich, Lavaughn Palma-Davis, Caroline R. Richardson
Evaluating Active U: An Internet-Mediated Physical Activity Program, Lorraine R. Buis, Timothy A. Poulton, Robert G. Holleman, Ananda Sen, Paul J. Resnick, David E. Goodrich, Lavaughn Palma-Davis, Caroline R. Richardson
Wayne State University Associated BioMed Central Scholarship
Abstract
Background
Engaging in regular physical activity can be challenging, particularly during the winter months. To promote physical activity at the University of Michigan during the winter months, an eight-week Internet-mediated program (Active U) was developed providing participants with an online physical activity log, goal setting, motivational emails, and optional team participation and competition.
Methods
This study is a program evaluation of Active U. Approximately 47,000 faculty, staff, and graduate students were invited to participate in the online Active U intervention in the winter of 2007. Participants were assigned a physical activity goal and were asked to record each physical …
Barriers Encountered During Enrollment In An Internet-Mediated Randomized Controlled Trial, Lorraine R. Buis, Adrienne W. Janney, Michael L. Hess, Silas A. Culver, Caroline R. Richardson
Barriers Encountered During Enrollment In An Internet-Mediated Randomized Controlled Trial, Lorraine R. Buis, Adrienne W. Janney, Michael L. Hess, Silas A. Culver, Caroline R. Richardson
Wayne State University Associated BioMed Central Scholarship
Abstract
Background
Online technology is a promising resource for conducting clinical research. While the internet may improve a study's reach, as well as the efficiency of data collection, it may also introduce a number of challenges for participants and investigators. The objective of this research was to determine the challenges that potential participants faced during the enrollment phase of a randomized controlled intervention trial of Stepping Up to Health, an internet-mediated walking program that utilized a multi-step online enrollment process.
Methods
We conducted a quantitative content analysis of 623 help tickets logged in a participant management database during the enrollment …
The Relationships Between Depression And Other Outcomes Of Chronic Illness Caregiving, Pao-Feng Tsai, Mary M. Jirovec
The Relationships Between Depression And Other Outcomes Of Chronic Illness Caregiving, Pao-Feng Tsai, Mary M. Jirovec
Wayne State University Associated BioMed Central Scholarship
Abstract
Background
Many caregivers with chronically ill relatives suffer from depression. However, the relationship of depression to other outcomes of chronic caregiving remains unclear. This study tested a hypothesized model which proposed that hours of care, stressful life events, social support, age and gender would predict caregivers' outcomes through perceived caregiver stress. Depression was expected to mediate the relationship between perceived stress and outcomes of chronic caregiving (physical function, self-esteem, and marital satisfaction).
Methods
The sample for this secondary data analysis consisted of 236 and 271 subjects from the Americans' Changing Lives, Wave 1, 1986, and Wave 2, 1989, data …