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Nursing

Master's Theses, Dissertations, Graduate Research and Major Papers Overview

2020

Pretreatment; succinylcholine; fasciculations; myalgia; depolarizing muscle relaxant; nondepolarizing muscle relaxant

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Comparing Pretreatment Modalities, Corey Mammen Nov 2020

Comparing Pretreatment Modalities, Corey Mammen

Master's Theses, Dissertations, Graduate Research and Major Papers Overview

This manuscript investigates the negative sequelae (in particular, myalgia) of using succinylcholine for patients undergoing tracheal intubation, pretreatment strategies to minimize or eliminate these untoward effects, and compare their efficacy. Various strategies are commonplace in the clinical setting, and there are a number of research studies that discuss the efficacy of individual agents as well as compare them against others. This manuscript explains the anatomy and physiology of neuromuscular junctions, muscle contraction, and their relationship with muscle relaxants used in the clinical setting.